Human Complement C4 ELISA Kit

Changes in serum complements and their regulators in generalized myasthenia gravis

• https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.14500
• Y Ozawa, A Uzawa, M Yasuda, Y Kojima...- European journal of..., 2021 - Wiley Online Library
• Objective To investigate changes in serum complements and their regulators in the pathogenesis of myasthenia gravis (MG). Methods Forty-four patients with acetylcholine receptor...

Could the complement component C4 or its fragment C4d be a marker of the more severe conditions in patients with primary Sj�gren's syndrome?

• https://link.springer.com/article/10.1007/s00296-013-2885-y
• G Sudzius, D Mieliauskaite, A Siaurys, R Viliene...- Rheumatology..., 2014 - Springer
• Our aim is to evaluate the complement component C4 (C4) and its fragment C4d (C4d) levels, focusing on their associations with other markers of B cells...activity in patients with primary...

High levels of soluble C5b-9 complex in dialysis fluid may predict poor prognosis in peritonitis in peritoneal dialysis patients

• https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169111
• M Mizuno, Y Suzuki, K Higashide, Y Sei, D Iguchi...- PLoS..., 2017 - journals.plos.org
• Background We searched for indicators to predict the prognosis of infectious peritonitis by measuring levels of complement proteins and activation products in peritoneal dialysis (PD)...

Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease

• https://link.springer.com/article/10.1186/1471-2164-15-904
• P Dowling, C Hayes, KR Ting, A Hameed, J Meiller...- BMC genomics, 2014 - Springer
• ...enzyme-linked immunosorbent assays for Human Complement C4 ELISA Kit (EC2102-1, Assaypro), Human Apolipoprotein B (EA7001-1, Assaypro) and Human Paraoxonase 1 (PON1...

Lymphatic Filariasis: Host and parasite factors and the pathogenesis of systemic adverse events following treatment

• https://openscholarship.wustl.edu/cgi/viewcontent.cgi?article=3202&context=art_sci_etds
• Andersone BJ (2020). Washington University in St. Louis Electronic Theses and Dissertations. 2160.
• No Snippet Provided

The status of the C3 fnd C4 fractions of the complement system in children with Henoch-Schelan purpura

• http://repo.knmu.edu.ua/bitstream/123456789/24629/1/PPED_Art_37761-10%20%281%29.pdf
• Chaika K et al. (2019). Pediatr Pol. 94 (4): 229-234.
• No Snippet Provided

FCN1 (M-fcolin), which directly associates with immunoglobulin G1, is a molecular target of intravenous immunoglobulin therapy for Kawasaki disease

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595863/pdf/41598_2017_Article_11108.pdf
• Okuzaki D et al. (2017). Sci Rep. 7(1):11334.
• No Snippet Provided

Methods for treating rheumatoid arthritis by administering IL-6 receptor antibodies

• http://www.freepatentsonline.com/10118967.html
• Hoefman S et al. (2018). United States Patent 10118967
• No Snippet Provided

Changes in the complement system in membranoproliferative glomerulonephritis

• https://cyberleninka.ru/article/n/izmeneniya-v-sisteme-komplementa-pri-membranoproliferativnom-glomerulonefrite
• Yurova BA et al. (2017). https://doi.org/10.17116/terarkh201789669-77.
• No Snippet Provided

Downregulation of the complement cascade in vitro, in mice and in patients with cardiovascular disease by the BET protein inhibitor apabetalone (RVX-208)

• https://link.springer.com/content/pdf/10.1007/s12265-017-9755-z.pdf
• Wasiak S et al. (2017). J. of Cardiovasc. Trans. Res. 10:337-347.
• No Snippet Provided

Activation of Complement System during Ship Voyage and Winter-over Expedition in Antarctica

• https://www.researchgate.net/profile/Dr-Narendra-Sharma/publication/286491592_Activation_of_Complement_System_during_Ship_Voyage_and_Winter-over_Expedition_in_Antarctica/links/5717778708ae2679a8c7705c/Activation-of-Complement-System-during-Ship-Voyage-and-Winter-over-Expedition-in-Antarctica.pdf
• Yadav AP et al. (2015). J Marine Sci Res Dev. 5:3.
• No Snippet Provided

Role of Anti-nucleosome Antibodies in the Diagnosis of Systemic Lupus Erythematosus and as A Marker for Lupus Nephropathy

• http://app.egyptlearn.com/eji/pdf/jan2014/6-Eman%20Ramadan2.pdf
• Gawad ERA (2014). THE EGYPTIAN JOURNAL OF IMMUNOLOGY 21(1):57-65
• No Snippet Provided

Diagnosis of spontaneous bacterial peritonitis

• http://www.esim.eg.net/temp/EgyptJInternMed26253-8239955_225319.pdf
• EI-Gendy NA et al. (2014). The Egyptian Journal of Internal Medicine 26(2):53-59
• No Snippet Provided

Non-alcoholic fatty liver disease. From patient to population

• https://repub.eur.nl/pub/40551
• Koehler EM (2013). Erasmus University Medical Center Rotterdam. Dissertation.
• No Snippet Provided

Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity

• http://onlinelibrary.wiley.com/doi/10.1002/oby.20327/full
• Guichelaar MMJ et al. (2013). Obesity 21(9):1935-1941
• No Snippet Provided

Growth hormone, dehydroepiandrosterone and adiponectin levels in non?alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients

• https://pubmed.ncbi.nlm.nih.gov/22098614/#affiliation-1
• Koehler E et al. (2012). Liver Int. 32(2):279-86
• No Snippet Provided

Serum Biomarkers For Early Detection Of Acute Cellular Rejection

• https://www.google.com/patents/US20120014949?dq=Serum+Biomarkers+For+Early+Detection+Of+Acute+Cellular+Rejection.+Patent+application+number:+20120014949&hl=en&sa=X&ei=X3RBVYj9L4rFsAXy04CIBQ&ved=0CB0Q6AEwAA
• Charlton MR (2012). Patent application number: 20120014949 A1
• No Snippet Provided

Noninvasive Diagnosis of Acute Cellular Rejection in Liver Transplant Recipients: A Proteomic Signature Validated by Enzyme-Linked Immunosorbent Assay

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293624/pdf/nihms263143.pdf
• Massoud O et al. (2011). Liver Transpl. 17(6):723-32.
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Biomarkers of hemorrhagic shock

• http://www.freepatentsonline.com/y2013/0149713.html
• Alam HB and Li Y (2011). Patent application number: 20130149713
• No Snippet Provided

Treatment of il-6r related diseases

• https://patents.google.com/patent/US20190119392A1/en
• Hoefman S et al. (2015). Patent application: US20190119392A1.
• No Snippet Provided

Changes in serum complements and their regulators in generalized myasthenia gravis.

• https://pubmed.ncbi.nlm.nih.gov/32889770/
• Y Ozawa, A Uzawa, ..., S Kuwabara (2021). European journal of neurology. 2021 Aug 11
• In the study investigating generalized myasthenia gravis, the Human Complement C4 AssayMax ELISA Kit facilitated the measurement of serum C4 levels, which was pivotal for exploring the…

Systems analysis-based assessment of post-treatment adverse events in lymphatic filariasis

• https://pubmed.ncbi.nlm.nih.gov/31557154/
• Britt J Andersen, Bruce A Rosa, ..., Gary J Weil (2019). PLoS Neglected Tropical Diseases. 2019 Sep 26
• m ( S2 Table ). Complement component 3 (C3), complement component 4 (C4) and Factor B (FB) were measured in the 36 samples (18 matched case-control subjects pre- and post-treatment) with ELISA kits (AssayPro, St. Charles, MO). The C3 and C4 assays were competitive enzyme immunoassays, and the FB assay was a sandwich ELISA. Each sample was tested in duplicate and manufacturer’s protocol was followe

FCN1 (M-ficolin), which directly associates with immunoglobulin G1, is a molecular target of intravenous immunoglobulin therapy for Kawasaki disease

• https://pubmed.ncbi.nlm.nih.gov/28900133/
• Kaori Ota, Shin-ichi Takatsuki, ..., Tsutomu Saji (2017). Scientific Reports. 2017 Sep 12
• Antibodies and reagents Antibodies against the following proteins were purchased from the indicated companies: OMG, METTL7B, MS4A7, and haptoglobin β (Santa Cruz Biotechnology); HSP90 and PRMT5 (Cell Signaling); S100A8 and haptoglobin α (Sigma-Aldrich); FAP (Abnova); α-Tubulin (MBL); GAPDH (Fitzgerald); C3 (BioLegend); C1q (Novus); and C4 (AssayPro).

Downregulation of the Complement Cascade In Vitro, in Mice and in Patients with Cardiovascular Disease by the BET Protein Inhibitor Apabetalone (RVX-208)

• https://pubmed.ncbi.nlm.nih.gov/28567671/
• Sylwia Wasiak, Dean Gilham, ..., Ewelina Kulikowski (2017). Journal of cardiovascular translational re…. 2017 May 31
• cultures were collected over the final 24 h of the experiment, flashed frozen in liquid nitrogen, and stored at −80 °C. C3, C4, C5, and C9 proteins were detected with ELISA kits as per the manufacturer’s instructions (AssayPro). Abundance of proteins secreted by Huh-7 and HepG2 were normalized to cell number (quantified with CellTiter 96® AQueous One Solution Cell Proliferation Assay (Promega)).

High Levels of Soluble C5b-9 Complex in Dialysis Fluid May Predict Poor Prognosis in Peritonitis in Peritoneal Dialysis Patients

• https://pubmed.ncbi.nlm.nih.gov/28046064/
• Masashi Mizuno, Yasuhiro Suzuki, ..., Cordula M. Stover (2017). PLoS ONE. 2017 Jan 03
• To measure levels of sC5b-9, C3 and C4 in PDF, we used the MicroVue TM sC5b-9 Plus EIA kit (Quidel Co., San Diego, CA), AssayMax Human Complement C3 ELISA kit and AssayMax Human Complement C4 ELISA kit (Assaypro LLC, St. Charles, MO), respectively.. These measurements were performed according to the manufacturer’s instructions.These measurements were performed according to ..

Incidence of Autoantibodies to C1Q Complement Component in Women with Miscarriages and Autoantibodies to Phospholipids and Chorionic Gonadotropin

• https://pubmed.ncbi.nlm.nih.gov/26639463/
• I V Menzhinskaya, L V Van'ko, ..., G T Sukhikh (2015). Bulletin of experimental biology and medic…. 2015 Dec 01
• Abstract: Autoantibodies to C1q complement component are often detected in patients with autoimmune diseases. The complement system is involved in the pathophysiology of gestosis. The incidence of ant…

Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy

• https://pubmed.ncbi.nlm.nih.gov/25725314/
• Yumi Sei, Masashi Mizuno, ..., Yasuhiko Ito (2015). Molecular immunology. 2015 Jun 01
• Abstract: We investigated the expression of membrane complement regulators (CRegs), CD46, CD55 and CD59 in human mesothelial cells, and correlated with clinical background and level of complement (C) …

Elevated Levels of the Complement Activation Product C4d in Bronchial Fluids for the Diagnosis of Lung Cancer

• https://pubmed.ncbi.nlm.nih.gov/25799154/
• Daniel Ajona, Cristina Razquin, ..., Ruben Pio (2015). PLoS ONE. 2015 Mar 23
• ing fragments of activated C4 (C4b, iC4b and/or C4d), which together are referred to in this paper as C4d. Quantitative enzyme-linked immunosorbent assays were also used for the determinations of C4 (Assaypro), C5a (R & D), and CYFRA 21-1 (DRG International). BAL samples were diluted 1:10, 1:1000, 1:100, and 1:25 for the analysis of C4d, C4, C5a, and CYFRA 21-1, respectively. Sputum specimens were

Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease

• https://pubmed.ncbi.nlm.nih.gov/25322877/
• Paul Dowling, Catriona Hayes, ..., Peter O’Gorman (2014). BMC Genomics. 2014 Oct 17
• Serum samples were screened using different enzyme-linked immunosorbent assays for Human Complement C4 ELISA Kit (EC2102-1, Assaypro), Human Apolipoprotein B (EA7001-1, Assaypro) and Human Paraoxonase 1 (PON1) (SK00141-01, Aviscera Bioscience, Inc).. Both Apo B100 and PON1 were assayed using a quantitative sandwich enzyme immunoassay technique, ..

Could the complement component C4 or its fragment C4d be a marker of the more severe conditions in patients with primary Sjögren's syndrome?

• https://pubmed.ncbi.nlm.nih.gov/24166212/
• Gintaras Sudzius, Diana Mieliauskaite, ..., Irena Dumalakiene (2014). Rheumatology international. 2014 Sep 29
• In the study examining primary Sjögren's syndrome, the Human Complement C4 AssayMax ELISA Kit from AssayPro was instrumental in measuring serum C4 levels. This analysis facilitated cru…

Diagnosis of spontaneous bacterial peritonitis

• https://link.springer.com/article/10.4103/1110-7782.139525
• Naglaa A. El-Gendy, Naglaa A. Tawfeek, ..., Rehab A. Mohammed (2014). The Egyptian Journal of Internal Medicine. 2014 Jun 01
• c Corporation (Immunospec, Los Angeles, California, USA) (Cat # E29-058). Th e range of the kit for adults was 0.068–8.2 mg/ml [15]. (3) C3 [16]and C4 [17] assays were performed using kits supplied by Assay Pro (Assay Pro LLC, St. Charles, Missouri, USA) (Cat#; EC2101-1 and EC2102-1), respectively, with reference ranges of 0.5–1.8 and 0.2–0.5 mg/ml, respectively. Statistical methods Statistical Pac

Interactions of Allelic Variance of PNPLA3 with Nongenetic Factors in Predicting Nonalcoholic Steatohepatitis and Nonhepatic Complications of Severe Obesity

• https://pubmed.ncbi.nlm.nih.gov/23418085/
• M M J Guichelaar, S Gawrieh, ..., M R Charlton (2013). Obesity (Silver Spring, Md.). 2013 Sep 24
• and tumor necrosis factor alpha (TNF-α). Other variables include cytokeratin-18 (CK-18) fragments (M30-Apoptosense® ELISA, Peviva AB, Sweden), complement C4 (cC4—AssayMax Himan complement C4 ELISA, Assaypro, MO), and human resistin (Human Resistin ELISA, Millipore, MA). Blood glucose concentrations were measured enzymatically with an autoanalyzer (Beckman Instruments, Fullerton, CA). All patients

Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients

• https://pubmed.ncbi.nlm.nih.gov/22098614/
• Edith Koehler, James Swain, ..., Michael Charlton (2011). Liver International. 2011 Sep 09
• Abstract: Liver-related clinical consequences of non-alcoholic fatty liver disease (NAFLD) are seen only in the minority of patients with advanced fibrosis. The aim of our study was to generate insigh…