Publications (77 results)
Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.Poly (ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease
Curcumin ameliorates diabetic nephropathy by suppressing NLRP3 inflammasome signaling
- https://onlinelibrary.wiley.com/doi/abs/10.1155/2017/1516985
- M Lu, N Yin, W Liu, X Cui, S Chen… - BioMed research …, 2017 - Wiley Online Library
- … assay (ELISA) kits for mouse albumin were acquired from Assaypro (St. Charles, MO, USA). … Urinary albumin concentration was measured using a mouse albumin ELISA kit (Assaypro, …
Leptin-mediated reactive oxygen species production does not significantly affect primary mouse hepatocyte functions in vitro
Poly (ADP-ribose) polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita mice
- https://www.spandidos-publications.com/ijmm/28/4/629
- VR Drel, P Pacher, R Stavniichuk… - International …, 2011 - spandidos-publications.com
- Poly (ADP-ribose) polymerase (PARP) activation has been implicated in the pathogenesis of diabetic complications, including nephropathy and peripheral neuropathy. This study …
MASP‐2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes
- https://onlinelibrary.wiley.com/doi/abs/10.1111/sji.13348
- H Charlotte Brinck, H Lene, D Tom… - Scandinavian …, 2024 - Wiley Online Library
- Mannan‐binding lectin (MBL) initiates the lectin pathway of complement and has been linked to albuminuria and mortality in diabetes. We hypothesize that MBL‐associated serine …
Identification of hepatocyte-primed cholangiocytes in the homeostatic liver by in vivo lentiviral gene transfer to mice and non-human primates
Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice
Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice
- https://karger.com/pha/article-abstract/88/1-2/88/271877
- LH Wang, JS Liu, WB Ning, QJ Yuan, FF Zhang… - Pharmacology, 2011 - karger.com
- Background/Aims: Fluorofenidone [1-(3-fluorophenyl)-5-methyl-2-(1H)-pyridone, AKF-PD], a novel pyridone agent, showed potent antifibrotic properties. The aim of the present study …
Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells …
Morphine promotes renal pathology in sickle mice
- https://www.tandfonline.com/doi/abs/10.2147/IJNRD.S33813
- ML Weber, D Vang, PE Velho, P Gupta… - … of Nephrology and …, 2012 - Taylor & Francis
- Patients with sickle cell disease (SCD) are often treated with opioids for severe pain. Although opioids are known to have renal-specific effects, their role in nephropathy in SCD remains …
Inflammatory cytokine TNFα promotes the long-term expansion of primary hepatocytes in 3D culture
- https://www.cell.com/cell/fulltext/S0092-8674(18)31504-6
- WC Peng, CY Logan, M Fish, T Anbarchian… - Cell, 2018 - cell.com
- In the healthy adult liver, most hepatocytes proliferate minimally. However, upon physical or chemical injury to the liver, hepatocytes proliferate extensively in vivo under the direction of …
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay
- https://www.embopress.org/doi/abs/10.1002/emmm.201201475
- L Fiorentino, M Cavalera, S Menini… - EMBO molecular …, 2013 - embopress.org
- … Urine albuminuria was determined using a mouse albumin ELISA kit (Assaypro, St. Charles, MO) and a mouse creatinine ELISA kit (Cusabio, Newark, DE) according to the …
Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited …
- https://www.mdpi.com/2073-4409/14/10/711
- J Gibson, A Dhungana, M Pokhrel, B Arthur, P Suresh… - Cells, 2025 - mdpi.com
- … the plated cells at 24 h after plating to quantify the secreted albumin using an AssayPro Mouse Albumin AssayMax ELISA kit (EMA3201-1, AssayPro, St. Charles, MO, USA). At 24 h after …
biomarkers for early diagnosis of sickle cell nephropathy
Fluorofenidone Offers Improved Renoprotection at Early Interventions during the Course of Diabetic Nephropathy in db/db Mice via Multiple Pathways
MAPEG expression in mouse embryonic stem cell-derived hepatic tissue system
- https://www.liebertpub.com/doi/abs/10.1089/scd.2007.0241
- DY Zhu, Y Du, X Huang, MY Guo, KF Ma… - Stem cells and …, 2008 - liebertpub.com
- The expressions of membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG), a superfamily involved in both inflammation and cell protection, were …
Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study
eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype
A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V‐ATPase a4 subunit in the proximal tubule
- https://www.embopress.org/doi/abs/10.1002/emmm.201201527
- JC Hennings, N Picard, AK Huebner… - EMBO molecular …, 2012 - embopress.org
- The V‐ATPase is a multisubunit complex that transports protons across membranes. Mutations of its B1 or a4 subunit are associated with distal renal tubular acidosis and deafness. In …
Plasmin improves blood–gas barrier function in oedematous lungs by cleaving epithelial sodium channels
Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress
Prevention of diabetic nephropathy in Ins2+/−AkitaJ mice by the mitochondria-targeted therapy MitoQ
FcγRIIb on myeloid cells and intrinsic renal cells rather than B cells protects from nephrotoxic nephritis
- no link
- PEH Sharp, J Martin-Ramirez… - The Journal of …, 2013 - American Association of …
- no snippet
Reduced beta 2 glycoprotein I improves diabetic nephropathy via inhibiting TGF-β1-p38 MAPK pathway
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4440048/
- T Wang, SS Chen, R Chen, DM Yu… - International journal of …, 2015 - pmc.ncbi.nlm.nih.gov
- … Urine albumin concentration was determined using the mouse albumin ELISA kit (Assaypro, USA) according to the manufacturer’s instructions. The serum levels of glucose, urea …
A double-hit pre-eclampsia model results in sex-specific growth restriction patterns
eNOS knockout mouse as a model of fetal growth
A new, easily generated mouse model of diabetic kidney fibrosis
- https://www.nature.com/articles/s41598-019-49012-4
- X He, T Zhang, M Tolosa, SK Goru, X Chen… - Scientific Reports, 2019 - nature.com
- … Prior to sacrifice, mice underwent 24 hour metabolic caging, and urinary albumin excretion was determined using an AssayMax mouse albumin ELISA kit (Assaypro, St. Charles, MO). …
Lgr5+ stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool
Consequences of surgical stress on the kinetics of skin wound healing: partial hepatectomy delays and functionally alters dermal repair
The potent antioxidant MitoQ protects against preeclampsia during late gestation but increases the risk of preeclampsia when administered in early pregnancy
- https://www.liebertpub.com/doi/abs/10.1089/ars.2019.7891
- Y Yang, P Xu, F Zhu, J Liao, Y Wu, M Hu… - Antioxidants & redox …, 2021 - liebertpub.com
- … EMA3201-1; Assaypro), whereas total urine protein levels were measured by using a BCA protein concentration test kit (Beyotime Biotechnology, Shanghai, China), both according to …
Articles in PresS. Am J Physiol Regul Integr Comp Physiol (May 2, 2012). doi: 10.1152/ajpregu. 00600.2011
Localization of type 1 17beta-hydroxysteroid dehydrogenase mRNA and protein in syncytiotrophoblasts and invasive cytotrophoblasts in the human term villi
- https://joe.bioscientifica.com/view/journals/joe/165/2/217.xml
- M Bonenfant, PR Provost, R Drolet… - Journal of …, 2000 - joe.bioscientifica.com
- The 17beta-hydroxysteroid dehydrogenases (17beta-HSDs) play a key role in the synthesis of sex steroids. The hallmark of this family of enzymes is the interconversion, through their …
Analysis of the expression pattern and knock-out phenotype of Slit-like 2 (Slitl2) in the mouse
- https://refubium.fu-berlin.de/handle/fub188/1977
- AM Mayer - 2011 - refubium.fu-berlin.de
- The murine Slit-like 2 (Slitl2) gene was first identified in 2002, and so far, no reports have been published on it. This thesis aimed at answering two basic questions when first analyzing …
Analysis of the expression pattern and knock-out phenotype of Slit-like 2 (Slitl2) in the mouse
- https://core.ac.uk/download/pdf/210658459.pdf
- AM Mayer - core.ac.uk
- Mouse embryonic development takes 19 days on average. It begins with a single cell, namely the fertilized egg, or zygote. The zygote undergoes cleavage divisions to form blastomeres…
Mouse liver assembloids model periportal architecture and biliary fibrosis
- https://www.nature.com/articles/s41586-025-09183-9
- AM Dowbaj, A Sljukic, A Niksic, C Landerer, J Delpierre… - Nature, 2025 - nature.com
- Modelling liver disease in vitro requires systems that replicate disease progression 1 , 2 . Current tissue-derived organoids do not reproduce the complex cellular composition and tissue …
Metabolic and Antioxidant Modulation by Artemisia indica Willd. Aqueous Extract in Glucose and Cholesterol Dysregulation
- https://www.mdpi.com/1422-0067/27/1/297
- CY Tseng, Y Wong, CC Chyau, YH Liang… - International Journal of …, 2025 - mdpi.com
- Artemisia indica Willd., a traditional medicinal and dietary herb, has been widely recognized for its diverse bioactivities. This study aimed to evaluate the effects of Artemisia indica Willd. …
食塩/アルドステロンによる心臓の炎症と線維化促進の分子機序: ASK1 を介する酸化ストレス亢進と組織レニン・アンジオテンシン系活性化の重要性
Targeting mitochondrial function in diabetic nephropathy
* Gibson J et al. (2025) Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease. Cells. 14(10):711. doi: 10.3390/cells14100711.
* Packialakshmi B et al. (2024) Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study Front Physiol. 15:1300667.
* Brinks R et al. (2023) Nrf2 Activation Does Not Protect from Aldosterone-Induced Kidney Damage in Mice. Antioxidants (Basel). 12(3):777
* Hu M et al. (2022) miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia. Mol Ther Nucleic Acids. 30:143-161.
* Belenguer G et al. (2022) RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state. Nat Commun. 13(1):334.
* Yang Y et al. (2021) The potent antioxidant MitoQ protects against preeclampsia during late gestation but increases the risk of preeclampsia when administered in early pregnancy. Antioxid Redox Signal. 34(2):118-136.
* Kostrzewski T et al. (2021) Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system. Commun Biol. 4(1):1080.
* Zimnol A et al. (2020) The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney. Antioxidants (Basel). 9(7):586.
* Stojanovska V et al. (2019) A double-hit pre-eclampsia model results in sex-specific growth restriction patterns. Dis Model Mech. 12(2):dmm035980.
* He X et al. (2019) A new, easily generated mouse model of diabetic kidney fibrosis. Sci Rep. 9(1):12549.
* Zhang Y et al. (2018) Reversing CXCL10 Deficiency Ameliorates Kidney Disease in Diabetic Mice. Am J Pathol. 188(12):2763-2773
* Zimnol A et al. (2017) Angiotensin II type 1a receptor-deficient mice develop angiotensin II-inducedoxidative stress and DNA damage without blood pressure increase. Am J Physiol Renal Physiol. 313(6): F1264-F1273.
* Zimnol A (2016) Relevance of the angiotensin II type 1a receptor and the NADPH oxidase for the creation Angiotensin II-mediated DNA damage. Julius Maximilians University of Wurzburg. Ph.D. Thesis.
* Peng ZW et al. (2016) Integrin avb6 Critically Regulates Hepatic Progenitor, Cell Function and Promotes Ductular Reaction, Fibrosis, and Tumorigenesis. Hepatology. 63(1): 217-232.
* Finn-Sell SL et al. (2016) The atrial natriuretic peptide (ANP) knockout mouse does not exhibit the phenotypic features of pre-eclampsia or demonstrate fetal growth restriction. Placenta. 42:25-27.
* Batchu SN et al. (2016) Prostaglandin I2 Receptor Agonism Preserves beta-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms. Diabetes. 65(5):1398-1409
* Wang T et al. (2015) Reduced beta 2 glycoprotein I improves diabetic nephropathy via inhibiting TGF-beta1-p38 MAPK pathway. Int J Clin Exp Pathol. 8(3):2321-2333
* Saetrom P (2014) Albumin production and cell proliferation. Patent application: EP20120730246.
* Rueda-Clausen CF et al. (2014) Effect of Prenatal Hypoxia in Transgenic Mouse Models of Preeclampsia and Fetal Growth Restriction. Reprod Sci. 21(4):492-502. Epub 2013 Sep 30.
* Reebye V et al. (2014) Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo. Hepatology. 59(1):216-27
* Sharp PE et al. (2013) FcGammaRIIb on Myeloid Cells and Intrinsic Renal Cells Rather than B Cells Protects from Nephrotoxic Nephritis. J Immunol. 190(1):340-8
* Poudel R et al. (2013) Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus. PLoS One. 8(5):e64401
* Fiorentino L et al. (2013) Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay. EMBO Mol Med. 2013 Mar;5(3):441-55. Epub 2013 Feb 12
* Zhang Y et al. (2012) Early-Outgrowth Bone Marrow Cells Attenuate Renal Injury and Dysfunction Via an Antioxidant Effect in a Mouse Model of Type 2 Diabetes. Diabetes. 61(8):2114-25
* Yuen DA et al.(2012) eNOS Deficiency Predisposes Podocytes to Injury in Diabetes. J Am Soc Nephrol. 2012 Nov;23(11):1810-23. doi: 10.1681/ASN.2011121170. Epub 2012 Sep 20
* Weber ML et al. (2012) Morphine promotes renal pathology in sickle mice. Int J Nephrol Renovasc Dis. 2012; 5: 109?118
* Stanley JL et al. (2012) Sildenafil citrate rescues fetal growth in the catechol-O-methyl transferase knockout mouse model. Hypertension. 59(5):1021-8. Epub 2012 Mar 5
* Sharp PE et al. (2012) Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells alone. Mol Immunol. 50(1-2):49-56
* Min JH et al. (2012) Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpression. Respir Res. 20;13:58
* Kusinski LC et al. (2012) eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype. Am J Physiol Regul Integr Comp Physiol303: R86-R93.
* Hennings JC et al. (2012) A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule. EMBO Mol Med. 4(10):1057-1071
* Wang LH et al. (2011) Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice. Pharmacology. 88(1-2):88-99
* Advani A et al. (2011) Long-Term Administration of the Histone Deacetylase Inhibitor Vorinostat Attenuates Renal Injury in Experimental Diabetes through an Endothelial Nitric Oxide Synthase-Dependent Mechanism. Am J Pathol. 178(5):2205-14. doi: 10.1016/j.ajpath.2011.01.044
* Shevalye H et al. (2010) Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease. Biochim Biophys Acta. 1802(11):1020-1027
* Nakamura Taishi (2010) The molecular mechanizm of aldosterone/sale-induced cardiac kin=flammation and fibrosis; critial role of the enhancement of cardiac oxidative stress and the activation of cardiac renin-angiotensin system, via apoptois signal regulating kinases 1 (ASK1). Kumamoto University. Doctoral Thesis.
* Chacko BK et al. (2010) Prevention of diabetic nephropathy in Ins2+/-AkitaJ mice by the mitochondria-targeted therapy MitoQ. Biochem. J. 432: 9?19
* Sorg H et al. (2009) Consequences of surgical stress on the kinetics of skin wound healing: Partial hepatectomy delays and functionally alters dermal repair. Wound Repair Regen. 17:367-377
* Zhu DY et al. (2008) MAPEG Expression in Mouse Embryonic Stem Cell-Derived Hepatic Tissue System. Stem Cells Dev. 17(4):775-783
