Human Tissue-type Plasminogen Activator (tPA) ELISA Kit

The rewards of nicotine: regulation by tissue plasminogen activatorplasmin system through protease activated receptor-1

• https://www.jneurosci.org/content/26/47/12374.short
• T Nagai, M Ito, N Nakamichi, H Mizoguchi - Journal of , 2006 - jneurosci.org
• Nicotine, a primary component of tobacco, is one of the most abused drugs worldwide. Approximately four million people die each year because of diseases associated with tobacco

Pleural Effusion and Plasma Levels of Fibrinolytic Parameters in Tuberculosis Pleurisy and Contribution to the Diagnosis.

• https://jag.journalagent.com/z4/download_fulltext.asp?pdir=eurasianjpulmonol&plng=eng&un=SOLUNUM-15010
• B Akkk, S Yurt, BA Yi?itba?, H Uzun - Eurasian Journal of , 2014 - jag.journalagent.com
• EF1040-1), t-PA/PAI-1 complex (Assaypro, USA, Catalogue No. EP1105-1), PAI-1 ( EP1100-1) and tPA (Assaypro, USA, Catalogue No. ET1001-1) were studied using commercial kits

The high-level expression of human tissue plasminogen activator in the milk of transgenic mice with hybrid gene locus strategy

• https://link.springer.com/article/10.1007/s12033-011-9428-0
• Y Zhou, Y Lin, X Wu, F Xiong, Y Lv, T Zheng - Molecular , 2012 - Springer
• The ELISA kits for the htPA antigen assay and activity assay both from AssayPro (cat no: ET1001-1 for antigen assay and cat no: CT1011 for activity assay). The high-prime DNA

Tberkloz Plrezide Fibrinolitik Parametrelerin Plevra S?v?s?, Plazmadaki Dzeyleri ve Tan?ya Katk?s?

• https://jag.journalagent.com/eurasianjpulmonol/pdfs/EJP_16_2_84_88[A].pdf
• B Akkk, S Yurt, BA Yi?itba?, H Uzun, F Ko?ar - 2014 - jag.journalagent.com
• Ama: Tberkloz ile hiperkoaglabilite aras?nda bir ili?ki oldu?u bildirilmi?tir. Hiperkoaglabilitenin olu?tu?u durumlarda vcut yan?t olarak fibrinolitik sistemi aktive etmektedir. Bu

ANALIZA ZWI?ZKU WYBRANYCH MARKERW KRZEPNI?CIA I FUNKCJI ?RDB?ONKA Z NIEWYDOLNO?CI? NEREK W GRUPIE CHORYCH Z

• https://www.ikard.pl/images/post%C4%99powania_w_sprawie_nadania_stopnia_doktora_/Lek.Paula_Polaska/Rozprawa_doktorska.pdf
• P Po?aska - ikard.pl
• Niewydolno?? serca [HF] jest z?o?onym zespo?em objaww klinicznych wynikaj?cych ze strukturalnej i/lub czynno?ciowej dysfunkcji mi??nia sercowego. Zgodnie z wytycznymi

Characterization of the human smooth muscle cell secretome for regenerative medicine

• https://www.liebertpub.com/doi/abs/10.1089/ten.TEC.2012.0054
• DM Justewicz, JE Shokes, B Reavis - Engineering Part C , 2012 - liebertpub.com
• Smooth muscle cells (SMC) play a central role in maintaining the structural and functional integrity of muscle tissue. Little is known about the early in vitro events that guide the assembly

Coagulation abnormalities as predictors of renal dysfunction in heart failure with reduced ejection fraction

• https://www.termedia.pl/Coagulation-abnormalities-as-predictors-of-renal-dysfunction-in-heart-failure-with-reduced-ejection-fraction,67,50945,1,1.html
• Polaska P et al. (2023). Medical Studies.39 (2): 148-158.
• No Snippet Provided

Drospirenone effects on the plasminogen activator system in immortalized human endometrial endothelial cells

• https://pubmed.ncbi.nlm.nih.gov/33559058/#affiliation-1
• Sabouni R et al. (2021). Reprod Sci. 28(7):1974-1980.
• No Snippet Provided

Effect of tranexamic acid on blood loss, coagulation profile, and quality of surgical field in intracranial meningioma resection: A prospective randomized, double-blind, placebo-controlled study

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247710/pdf/SNI-12-272.pdf
• Ravi GK et al. (2021). Surg Neurol Int. 12:272.
• No Snippet Provided

Arsenite Inhibits Tissue-Type Plasminogen Activator Synthesis through NRF2 Activation in Cultured Human Vascular Endothelial EA.hy926 Cells

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7828481/pdf/ijms-22-00739.pdf
• Nakano T et al. (2021). Int J Mol Sci. 22(2):739.
• No Snippet Provided

Regular Resistance Training Enhances Fibrinolytic Potential but Does Not Affect Coagulation

• https://www.researchgate.net/profile/Andrew-Del-Pozzi-2/publication/352344312_Regular_Resistance_Training_Enhances_Fibrinolytic_Potential_but_Does_Not_Affect_Coagulation/links/61a67d0a743d9629db276cdc/Regular-Resistance-Training-Enhances-Fibrinolytic-Potential-but-Does-Not-Affect-Coagulation.pdf
• Nagelkirk PR et al.(2021). Med Sci Sports Exerc. 53(11):2318-2323.
• No Snippet Provided

Post-traumatic stress disorder: A biopsychosocial case-control study investigating peripheral blood protein biomarkers

• https://reader.elsevier.com/reader/sd/pii/S2666144621000137?token=7EF55B352787EC67B5699AA8761C0CD43FBE0B5B3E310821455C29F760A19311BC22C8DB12D34B1527C5D621AFADFD5E&originRegion=us-east-1&originCreation=20211008214102
• Maguire D et al. (2021). Biomarkers in Neuropshchiatry 5:100042.
• No Snippet Provided

Cadmium induces plasminogen activator inhibitor-1 via Smad2/3 signaling pathway in human endothelial EA. hy926 cells

• https://www.jstage.jst.go.jp/article/jts/46/5/46_249/_pdf
• Hara T et al. (2021). J.Toxicol.Sci. 46(5):249-253.
• No Snippet Provided

Alu-repeat polymorphism in the tissue plasminogen activator (t-PA) gene, seminal t-PA concentration, and male fertility impairment: A case-control study

• https://pmc.ncbi.nlm.nih.gov/articles/PMC7457157/pdf/ijrb-18-571.pdf
• Tahtamouni LH et al. (2020). Int J Reprod Biomed. 18(8):571-578.
• No Snippet Provided

Hemostatic Adaptations to High Intensity Interval Training in Healthy Adult Men

• https://pubmed.ncbi.nlm.nih.gov/32634847/#affiliation-1
• Sackett JR et al. (2020). Int J Sports Med. 41(12):867-872.
• No Snippet Provided

Acute fbrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

• https://annalsofintensivecare.springeropen.com/track/pdf/10.1186/s13613-019-0499-6.pdf
• Schmitt FCF et al. (2019). Ann. Intensive Care. 9:19.
• No Snippet Provided

Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311307/pdf/BMRI2018-3205324.pdf
• Siennicka A et al. (2018). Biomed Res Int. 2018: 3205324.
• No Snippet Provided

Tissue factor levels and the fibrinolytic system in thin and thick intraluminal thrombus and underlying walls of abdominal aortic aneurysms

• https://www.sciencedirect.com/science/article/pii/S0741521418301332.
• Siennicka A et al. (2018). Journal of Vascular Surgery.
• No Snippet Provided

Comprehensive analysis of haemostatic profile depending on clinicopathological determinants in breast cancer patients

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874264/pdf/bsr-38-bsr20171657.pdf
• Rhone P (2018). Biosci Rep. 29;38(2)
• No Snippet Provided

Short chain fatty acids induce tissue plasminogen activator in airway epithelial cells via GPR 41&43

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987538/pdf/nihms968073.pdf
• Imoto Y et al. (2018). Clin Exp Allergy. 48(5): 544-554.
• No Snippet Provided

A combined therapy of rtPA-loaded thermoresponsive gels and ultrasound on hematoma in a rat model of intracerebral hemorrhage

• https://pubs.rsc.org/en/content/articlepdf/2017/ra/c6ra23150k
• Sun W et al. (2017). RSC Adv. 7:15809-15816.
• No Snippet Provided

Relationship between circulating tumor cells and tissue plasminogen activator in patients with early breast cancer

• https://ar.iiarjournals.org/content/anticanres/37/4/1787.full.pdf
• Bystricky B et al. (2017). Anticance Res. 37(4): 1787-1791.
• No Snippet Provided

Intervention of chlorogenic acid, caffeic acid and ferulic acid on the expression of inflammation-related molecules in endothelial cells caused by complement bypass activation. Chi.Pharma

• http://html.rhhz.net/ZGYLXTB/html/201612017.htm
• Zhou Y et al. (2016). Bulletin. 32(12): 1723-1728.
• No Snippet Provided

Hemostatic markers and long-term risk of intracerebral hemorrhage in postmenopausal women

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912397/pdf/nihms770660.pdf
• Lee JM (2016). J Stroke Cerebrovasc Dis. 25(7): 1639-1643.
• No Snippet Provided

Simultaneous Consideration of Multiple Candidate Protein Biomarkers for Long-Term Risk for Cardiovascular Events

• https://circgenetics.ahajournals.org/content/8/1/168.full.pdf?download=true
• Halim SA et al. (2015). Circ Cardiovasc Genet. 8(1):168-77
• No Snippet Provided

Effects of hormone replacement therapy on plasma and tissue fibrinolytic activity in a rat model of surgically induced menopause

• https://www.ncbi.nlm.nih.gov/pubmed/24690423
• Topcuoglu A et al. (2014). Clin Invest Med. 2014 Apr 1;37(2):E85-92
• No Snippet Provided

Pleural effusion and plasma levels of fibrinolytic parameters in tuberculosis pleurisy and contribution to the diagnosis

• http://www.journalagent.com/eurasianjpulmonol/pdfs/EJP_16_2_84_88.pdf
• Akkok B et al. (2014). Eurasian J Pulmonol. 16: 84-88
• No Snippet Provided

Pleural effusion and plasma levels of fibrinolytic parameters in tuberculosis pleurisy and contribution to the diagnosis

• http://www.journalagent.com/eurasianjpulmonol/pdfs/EJP_16_2_84_88.pdf
• Akkok B et al. (2014). Eurasian J Pulmonol. 16: 84-88
• No Snippet Provided

Interaction of Leptospira interrogans with Human Proteolytic Systems Enhances Dissemination through Endothelial Cells and Protease Levels

• https://iai.asm.org/content/iai/81/5/1764.full.pdf
• Vieira ML et al. (2013). Infect Immun. 81(5):1764-74. doi: 10.1128/IAI.00020-13. Epub 2013 Mar 11
• No Snippet Provided

Excessive fibrin deposition in nasal polyps caused by fibrinolytic impairment through reduction of tissue plasminogen activator expression

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570641/pdf/AJRCCM187149.pdf
• Takabayashi T et al. (2013). Am J Respir Crit Care Med. 187(1):49-57.
• No Snippet Provided

Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant?

• http://www.jpp.krakow.pl/journal/archive/06_13/pdf/321_06_13_article.pdf
• Siennicka A et al. (2013). J Physiol Pharmacol. 64(3):321-30
• No Snippet Provided

Effect of a Congolese herbal medicine used in sickle cell anemia on the expression of plasminogen activators in human coronary aortic endothelial cells culture

• https://www.sciencedirect.com/science/article/abs/pii/S0378874113000603
• Nsimba MM et al. (2013). J Ethnopharmacol. 146(2):594-9
• No Snippet Provided

Assessment of some plasma fibrinolytic proteins in sickle cell anemia patients in steady state and in vaso-occlusive crises

• http://www.jahjournal.org/temp/JApplHematol44131-5092436_140844.pdf
• Ekwere T et al. (2013). Journal of Applied Hematology. 4(4):131-136
• No Snippet Provided

Pharmacokinetics and thrombolytic effects of the recombinant tissue-type plasminogen activator in horses

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750949/pdf/1746-6148-9-158.pdf
• Baumer W et al. (2013). BMC Veterinary Research 9:158
• No Snippet Provided

Activation of coagulation, anti-coagulation, fibrinolysis and the complement system in patients with urticaria

• http://apjai.digitaljournals.org/index.php/apjai/article/viewFile/900/1098
• Zhu H et al. (2012). Asian Pac J Allergy Immunol 31:43-50
• No Snippet Provided

The high-level expression of human tissue plasminogen activator in the milk of transgenic mice with hybrid gene locus strategy

• https://pubmed.ncbi.nlm.nih.gov/21688038/#affiliation-1
• Zhou Y et al. (2012). Mol Biotechnol. 50(2):137-44.
• No Snippet Provided

The interaction of Leptospira interrogans with juman proteolytic system enhaces dissemination through endothelial cells and the levels of plasminogen activators and matrix metalloprotease-9

• https://www.teses.usp.br/teses/disponiveis/87/87131/tde-13122012-141110/publico/MonicaLarucciVieira_Doutorado.pdf
• Vieira ML et al. (2012). University of Sao Paulo.
• No Snippet Provided

A novel fibrinogenase from Agkistrodon acutus venom protects against DIC via direct degradation of thrombosis and activation of protein C

• https://pubmed.ncbi.nlm.nih.gov/22728069/#affiliation-1
• Qi J et al. (2012). Biochem Pharmacol. 84(7):905-13.
• No Snippet Provided

Plasma levels of platelet-derived microparticles are increased after anaerobic exercise in healthy subjects

• https://www.jstage.jst.go.jp/article/jat/19/6/19_11791/_pdf/-char/en
• Maruyama K et al. (2012). J Atheroscler Thromb. 19 (6):585-587
• No Snippet Provided

Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke

• https://pubmed.ncbi.nlm.nih.gov/20889155/#affiliation-1.
• Tuttolomondo A et al. (2010). Atherosclerosis. 213(1):311-8.
• No Snippet Provided

Ezetimibe Therapy and Its Influence on Oxidative Stress and Fibrinolytic Activity

• https://insights.ovid.com/article/00007611-201005000-00011
• Turfaner N et al. (2010). South Med J. 103:428-433
• No Snippet Provided

GnRH receptor and peritoneal plasmin activity

• https://pubmed.ncbi.nlm.nih.gov/20236028/#affiliation-1
• Suzuki N et al. (2010). Gynecol Endocrinol. 26(9):669-672
• No Snippet Provided

HMG-CoA reductase inhibitor lovastatin upregulates plasminogen activator production through RhoA-signaling in peritoneal cell line Met5A

• https://gynecolsurg.springeropen.com/track/pdf/10.1007/s10397-009-0546-7.pdf
• Suzuki N and Imai A (2010). Gynecol Surg. 7:189-193.
• No Snippet Provided

Neuroserpin, a thrombolytic serine protease inhibitor (serpin), blocks transplant vasculopathy with associated modification of T-helper cell subsets

• https://www.thieme-connect.com/products/ejournals/abstract/10.1160/TH09-07-0441
• Munuswamy-Ramanujam G et al. (2010). Thromb Haemost. 103(3):545-555
• No Snippet Provided

Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects

• http://www.jbc.org/content/285/7/4366.full.pdf+html
• Kesavan K et al. (2010). J Biol Chem. 285(7):4366-4374
• No Snippet Provided

Hypertension and hemostatic/fibrinolytic balance disorders

• https://pubmed.ncbi.nlm.nih.gov/20003834/
• Tabak O et al. (2009). Clin Invest Med. 32(6):E285
• No Snippet Provided

Prostaglandin E2 acts via multiple receptors to regulate plasminogen-dependent proteolysis in the primate periovulatory follicle

• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630891/
• Markosyan N and Duffy DM (2009). Endocrinology. 150(1):435-44
• No Snippet Provided

Activated protein C ratio, plasma tissue factor activity and activated factor VII in Chinese patients with coronary heart disease

• https://pubmed.ncbi.nlm.nih.gov/18424361/#affiliation-1
• He WJ et al. (2008). Eur J Med Res. 13:47-51
• No Snippet Provided

Is Familial Mediterranean Fever a thrombotic disease or not?

• https://pubmed.ncbi.nlm.nih.gov/17436016/#affiliation-1
• Demirel A et al. (2008). Eur J Pediatr. 167(3):279-285
• No Snippet Provided

Glucose-Based PD Solution, But Not Icodextrin-Based PD Solution, Induces Plasminogen Activator Inhibitor-1 and Tissue-Type Plasminogen Activator in Human Peritoneal Mesothelial Cells via ERK1/2

• https://pubmed.ncbi.nlm.nih.gov/17381529/
• Katsutani M et al. (2007). Ther Apher Dial. 11(2): 94-100.
• No Snippet Provided

The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1

• http://www.jneurosci.org/content/26/47/12374.full.pdf
• Nagai T et al. (2006). The Journal of Neuroscience 26(47):12374-12383
• No Snippet Provided

Lysophosphatidylcholine induces tPA gene expression through CRE-dependent mechanism

• https://pubmed.ncbi.nlm.nih.gov/15721275/
• Sheikh AM et al. (2005). Biochem Biophys Res Commun. 329(1):71-77
• No Snippet Provided

Experience-Dependent Pruning of Dendritic Spines in Visual Cortex by Tissue Plasminogen Activator

• https://pubmed.ncbi.nlm.nih.gov/15603745/
• Mataga N et al. (2004). Neuron 44:1031-1041
• No Snippet Provided

Coagulation abnormalities as predictors of renal dysfunction in heart failure with reduced ejection fraction

• No Link Provided
• Paula Połaska, Ilona Kowalik, ..., Tomasz Rywik (2023). Medical Studies. 2023 Jan 01
• .. PAI-1 ELISA. sTM was measured using an enzyme-linked immunoassay (Diaclone sCD141 ELISA Kit, France).. The concentration of tissue plasminogen activator (tPA) was determined by enzymelinked immunoassay (AssayMaxTM Human tPA ELISA Kit, AssayPro, United States).. Other tests were carried out at the institute’s central laboratory.Other tests were carried out ..

Drospirenone Effects on the Plasminogen Activator System in Immortalized Human Endometrial Endothelial Cells.

• https://pubmed.ncbi.nlm.nih.gov/33559058/
• Reem Sabouni, David F Archer, Terry Jacot (2022). Reproductive sciences (Thousand Oaks, Cali…. 2022 Jan 10
• In the study, the Human Tissue type Plasminogen Activator tPA AssayMax ELISA Kit from Assaypro was employed to measure tPA levels in the culture media of HEECs treated with drospirenon…

Post-traumatic Stress Disorder: A Biopsychosocial Case-control Study Investigating Peripheral Blood Protein Biomarkers

• No Link Provided
• Daniel Maguire, Joanne Watt, Mark W. Ruddock (2021). Biomarkers in Neuropsychiatry. 2021 Sep 01
• e analysed on a Cobas Analyser (Roche, Basel, Switzerland). Human tissue-type plasminogen activator (tPA) and human type-1 plasminogen activator inhibitor (PAI1/tPA) complex ELISAs were obtained from AssayPro (St. Charles, Missouri, USA). Midkine ELISAs were obtained from CellMid, (Sydney, Australia). Assays were completed according to manufacturer’s instructions. The limits of detection (LOD) for

Regular Resistance Training Enhances Fibrinolytic Potential but Does Not Affect Coagulation

• https://pubmed.ncbi.nlm.nih.gov/34115732/
• Paul R Nagelkirk, Kayla Soave, ..., Andrew Del Pozzi (2021). Medicine Science in Sports Exercise. 2021 Jun 10
• Abstract: This study aimed to identify effects of an 8-wk, whole-body RT program on coagulation and fibrinolysis. Sixteen healthy women and men (23 ± 5 yr) completed an RT program three times per week…

Effect of tranexamic acid on blood loss, coagulation profile, and quality of surgical field in intracranial meningioma resection: A prospective randomized, double-blind, placebo-controlled study

• https://pubmed.ncbi.nlm.nih.gov/34221603/
• Gopala K Ravi, Nidhi Panda, ..., Shalvi Mahajan (2021). Surgical Neurology International. 2021 Jun 07
• and D-dimer levels were measured using Claus method and Latex Immunoassay, respectively. The tissue plasminogen activator level was assessed using a commercial enzyme-linked immunosorbent assay kit (Assaypro, Missouri, USA). The infusion of tranexamic acid was stopped at the end of the surgery just before skin closure. Arterial blood sample was evaluated for “Final hematocrit” estimation at the e

Arsenite Inhibits Tissue-Type Plasminogen Activator Synthesis through NRF2 Activation in Cultured Human Vascular Endothelial EA.hy926 Cells

• https://pubmed.ncbi.nlm.nih.gov/33451022/
• Tsuyoshi Nakano, Tsutomu Takahashi, ..., Yasuyuki Fujiwara (2021). International Journal of Molecular Science…. 2021 Jan 13
• thelial EA.hy926 cells treated with 1, 2, 5, or 10 µM arsenite for 24 h at 37 °C in a 24-well culture plate was used to measure t-PA and PAI-1 secretion with an enzyme-linked immunosorbent assay kit (AssayPro LLC, St. Charles, MO, USA), after which the cell layer was analyzed for DNA content using a fluorometric method [ 58 ] to normalize the t-PA and PAI-1 content in the conditioned medium per µg

Cadmium induces plasminogen activator inhibitor-1 via Smad2/3 signaling pathway in human endothelial EA.hy926 cells

• https://pubmed.ncbi.nlm.nih.gov/33952801/
• Takato Hara, Miki Sakuma (2021). The Journal of toxicological sciences. 2021 Jan 01
• Fibrinogen and thrombin from human plasma were purchased from Sigma-Aldrich (St. Louis, MO, USA).. Enzyme-linked immunosorbent assay (ELISA) kits for human t-PA and PAI-1 were purchased from Assaypro LLC (St. Charles, MO, USA).. ISOGEN-II, GeneAce SYBR qPCR mix α, and negative control siRNA were purchased from Nippon ..

Hemostatic Adaptations to High Intensity Interval Training in Healthy Adult Men

• https://pubmed.ncbi.nlm.nih.gov/32634847/
• James R Sackett, Dan P Farrell, Paul R Nagelkirk (2020). International journal of sports medicine. 2020 Jul 07
• Abstract: Regular exercise is theorized to reduce cardiovascular risk by attenuating coagulation and augmenting fibrinolysis. However, these adaptations have not been consistently observed during trad…

Tissue factor levels and the fibrinolytic system in thin and thick intraluminal thrombus and underlying walls of abdominal aortic aneurysms.

• https://pubmed.ncbi.nlm.nih.gov/29571624/
• Aldona Siennicka, Marta Zuchowski, ..., Maria Jastrzębska (2019). Journal of vascular surgery. 2019 Mar 14
• .. aortic tissue homogenates, as follows: TF activity: AssaySense Human TF Chromogenic Activity Assay Kit (AssayPro, St. Charles, Mo); plasmin activity: SensoLyte AFC Plasmin Activity Assay Kit (AnaSpec, Fremont, Calif); tPA concentrations: AssayMax Human tPA ELISA kit (AssayPro); plasminogen concentrations: AssayMax Human Plasminogen ELISA kit (AssayPro); PAI-1 concentrations: AssayMax Human PAI-1 ELISA Kit (AssayPro); a2AP concentrations: Human Alpha-2Antiplasmin, Alpha-2-AP ELISA Kit (Wuhan EIAab Science Co, Ltd, Wuhan, China). ..

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

• https://pubmed.ncbi.nlm.nih.gov/30701381/
• Felix Carl Fabian Schmitt, Vasil Manolov, ..., Thorsten Brenner (2019). Annals of Intensive Care. 2019 Jan 30
• Plasma levels of thrombin–antithrombin complex (TAT), plasminogen activator inhibitor 1 (PAI-1), free tissue plasminogen activator (tPA) and total tissue plasminogen activator (total tPA) were measured using enzyme-linked immunosorbent assay (ELISA) kits according to the manufacturer’s instructions (Assaypro, St. Charles, USA). ELISA measurements were performed in duplicate.

Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro

• https://pubmed.ncbi.nlm.nih.gov/30643799/
• Aldona Siennicka, Marta Zuchowski, ..., Maria Jastrzębska (2018). BioMed Research International. 2018 Dec 12
• A) were used to measure haemostatic parameters in aortic tissue homogenates. A microplate reader (EnVision Multilabel Plate Reader; PerkinElmer, USA) and manufacturer's instructions of kits (all from AssayPro, St. Charles, Missouri, USA) were followed to determine: Tissue factor activity (AssaySense Human Tissue Factor (TF) Chromogenic Activity Assay Kit); tissue plasminogen activator (t-PA) concen

Short-chain fatty acids induce tissue plasminogen activator in airway epithelial cells via GPR41 43

• https://pubmed.ncbi.nlm.nih.gov/29431874/
• Y Imoto, A Kato, ..., R P Schleimer (2018). Clinical and experimental allergy : journa…. 2018 May 22
• t-PA in tissue homogenate and the supernatants of cultured cells were determined with a commercially available enzyme-linked immunosorbent assay (ELISA) kit according to the manufacturer's protocol (Assaypro, St. Charles, MO). The absorbance was measured using a Bio-Rad Spectrophotometer Model 680 Microplate Reader (Bio-Rad, Hercules, CA) with associated software applied to the sandwich enzyme imm

Comprehensive analysis of haemostatic profile depending on clinicopathological determinants in breast cancer patients

• https://pubmed.ncbi.nlm.nih.gov/29475895/
• Piotr Rhone, Barbara Ruszkowska-Ciastek, ..., Danuta Rość (2018). Bioscience Reports. 2018 Mar 29
• .. ELISA test Kit 96- Well Plate Assay, Sekisui Diagnostics, LLC, Stamford, CT, USA, respectively.. However, the concentration of tissue plasminogen activator (t-PA) was assayed with the AssayMax™ Human t-PA ELISA Kit, Assaypro LLC, St. Charles, MO, USA.. Additionally, the plasma activities of TF and TFPI were measured using chromogenic assays, the ..

Relationship Between Circulating Tumor Cells and Tissue Plasminogen Activator in Patients with Early Breast Cancer

• https://pubmed.ncbi.nlm.nih.gov/28373442/
• Branislav Bystricky, Silvia Jurisova, ..., Michal Mego (2017). Anticancer research. 2017 Apr 01
• Plasma tPA was analyzed using a commercial enzyme-linked immunosorbent assay (ELISA).. Human tPA ELISA kit (Assaypro LLC, St. Charles, MO, USA) was used according to the instructions of the manufacturer.. The intra- and inter-assay coefficients of variation are below 5% and 10%, respectively.

A combined therapy of rtPA-loaded thermoresponsive gels and ultrasound on hematoma in a rat model of intracerebral hemorrhage

• No Link Provided
• Wei Sun, Zhongxin Qian, ..., Weidong Liu (2017). RSC Advances. 2017 Jan 01
• In the study, a recombinant tissue-type plasminogen activator (rtPA)-loaded Pluronic F127 (NP-rtPA) delivery system was developed and used to evaluate its effectiveness in dissolving i…

Hemostatic markers and long-term risk of intracerebral hemorrhage in postmenopausal women

• https://pubmed.ncbi.nlm.nih.gov/27067884/
• Ju-Mi Lee, Juned Siddique, ..., Philip Greenland (2016). Journal of stroke and cerebrovascular dise…. 2016 Apr 07
• For the ratio calculation, VWF (U/ml) was divided by ADAMTS13 (μg/ml).. Tissue plasminogen activator (t-PA, IU/ml) was measured using an ELISA kit (Assaypro LLC, St Charles, Missouri).. Urokinase plasminogen activator (u-PA, IU/ml) was quantitated using a chromogenic activity assay (u-PA Human ..

Simultaneous Consideration of Multiple Candidate Protein Biomarkers for Long-Term Risk for Cardiovascular Events

• https://pubmed.ncbi.nlm.nih.gov/25422398/
• Sharif A Halim, Megan L Neely, ..., L Kristin Newby (2015). Circulation. Cardiovascular genetics. 2015 Feb 28
• In the study examining cardiovascular risk markers, the Human Tissue-type Plasminogen Activator (tPA) AssayMax ELISA Kit from Assaypro played a crucial role in measuring various plasma…

Pleural Effusion and Plasma Levels of Fibrinolytic Parameters in Tuberculosis Pleurisy and Contribution to the Diagnosis

• No Link Provided
• Burcu Akkok, Sibel Yurt, ..., Filiz Kosar (2014). Eurasian Journal of Pulmonology. 2014 Sep 02
• Plasma and pleural fluid D-Dimer (HYPHEN Biomed, D-Dimer, Catalogue Number: RK023A), fibrinogen (Assaypro, USA, Catalogue No. EF1040-1), t-PA/PAI-1 complex (Assaypro, USA, Catalogue No. EP1105-1), PAI-1 (Assaypro, USA, Catalogue No.EP1100-1) and tPA (Assaypro, USA, Catalogue No. ET1001-1) were studied using commercial kits based on the principle of competitive ELISA.

Effects of Hormone Replacement Therapy on Plasma and Tissue Fibrinolytic Activity in a Rat Model of Surgically Induced Menopause

• https://pubmed.ncbi.nlm.nih.gov/24690423/
• Ata Topcuoglu, Mustafa Albayrak, ..., Hafize Uzun (2014). Clinical Investigative Medicine. 2014 Apr 01
• the various analytes were assayed using the supernatant fraction. Assay of tPA, PAI-1 and tPA/PAI-1 levels tPA, PAI-1, and tPA/PAI-1 levels in plasma and tissues (brain and liver) were measured using Assaypro ELISA kits according to the manufacturer’s instructions (AssayMax ELISA kit; Assaypro, Win eld, MO, USA). Estradiol in serum was measured using the Chemiluminescent Microparticle Immunoassay (

Pharmacokinetics and thrombolytic effects of the recombinant tissue-type plasminogen activator in horses

• https://pubmed.ncbi.nlm.nih.gov/23938183/
• Wolfgang Bäumer, Gudrun M Herrling, Karsten Feige (2013). BMC Veterinary Research. 2013 Aug 09
• of a refractometer (Euromex, Arnheim, Netherlands). The determination of rt-PA was performed via enzyme linked immunosorbant assay (ELISA) (AssayMax Human Tissue-Type Plasminogen Activator ELISA Kit, Assay Pro, St. Charles, MO, USA). The standard calibration was carried out in horse plasma diluted 1:10 with dilution media, as the instructions of the test kit required dilution of at least 1:10 to mi

Interaction of Leptospira interrogans with Human Proteolytic Systems Enhances Dissemination through Endothelial Cells and Protease Levels

• https://pubmed.ncbi.nlm.nih.gov/23478319/
• Monica L Vieira, Miryam P Alvarez-Flores, ..., Ana L T O Nascimento (2013). Infection and Immunity. 2013 May 23
• Human serum samples were quantified as uPA and tPA (tissue-type plasminogen activator) by using commercial kits based on the capture enzyme-linked immunosorbent assay (ELISA) (AssayMax human urokinase and AssayMax human tissue-type plasminogen activator from Assaypro). The protocols were performed as recommended by the manufacturer.

Excessive Fibrin Deposition in Nasal Polyps Caused by Fibrinolytic Impairment through Reduction of Tissue Plasminogen Activator Expression

• https://pubmed.ncbi.nlm.nih.gov/23155140/
• Tetsuji Takabayashi, Atsushi Kato, ..., Robert P Schleimer (2013). American journal of respiratory and critic…. 2013 Jan 01
• The plasminogen activators u-PA and t-PA (Assaypro, St. Charles, MO), eosinophilic cationic protein (ECP) (MBL, Woburn, MA), and d-dimer (Diagnostica Stago, Asnieres-Sur-Seine, France) were assayed with specific ELISA kits as detailed in the online supplement.

A novel fibrinogenase from Agkistrodon acutus venom protects against DIC via direct degradation of thrombosis and activation of protein C.

• https://pubmed.ncbi.nlm.nih.gov/22728069/
• Jie-zhen Qi, Xi Lin, ..., Guang-mei Yan (2012). Biochemical pharmacology. 2012 Nov 01
• In the study investigating a novel fibrinogenase's protective effects against DIC, the Human Tissue type Plasminogen Activator tPA AssayMax ELISA Kit from Assaypro was essential in qua…

The high-level expression of human tissue plasminogen activator in the milk of transgenic mice with hybrid gene locus strategy.

• https://pubmed.ncbi.nlm.nih.gov/21688038/
• Yanrong Zhou, Yanli Lin, ..., Hongxing Chen (2012). Molecular biotechnology. 2012 May 21
• In the study, the Human Tissue type Plasminogen Activator tPA AssayMax ELISA Kit from Assaypro was instrumental in quantifying the expression levels of recombinant human tissue plasmin…

Plasma Levels of Platelet-Derived Microparticles are Increased After Anaerobic Exercise in Healthy Subjects

• https://pubmed.ncbi.nlm.nih.gov/22362079/
• Keiko Maruyama, Tadaaki Kadono, Eriko Morishita (2012). Journal of atherosclerosis and thrombosis. 2012 Jan 01
• immediately and 1 hour after the exercise test. The plasma levels of PDMP were determined by an ELISA kit (Jimro Co. Ltd.). To examine fibrinolysis and coagulation, the plasma levels of t-PA antigen (Assay Pro), plasminogen activator inhibitor type 1 (PAI-1) antigen and soluble fibrin (SF) (Mitsubishi Chemical Medience) were measured. The study followed the institutional guidelines of the Universit

Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke

• https://pubmed.ncbi.nlm.nih.gov/24571954/
• Antonino Tuttolomondo, Domenico Di Raimondo, ..., Giuseppe Licata (2010). Atherosclerosis. 2010 Nov 01
• In the study of acute ischemic stroke patients, the Human Tissue-type Plasminogen Activator (tPA) AssayMax ELISA Kit from Assaypro was essential for quantifying plasma levels of tissue…

Ezetimibe Therapy and Its Influence on Oxidative Stress and Fibrinolytic Activity

• https://pubmed.ncbi.nlm.nih.gov/20375933/
• Nurver Turfaner, Hafize Uzun, ..., Habibe Genc (2010). Southern Medical Journal. 2010 May 01
• In the study, the Human Tissue-type Plasminogen Activator (tPA) AssayMax ELISA Kit played a critical role by enabling the measurement of tPA levels in patients treated with ezetimibe, …

GnRH receptor and peritoneal plasmin activity

• https://pubmed.ncbi.nlm.nih.gov/20236028/
• Noriko Suzuki, Akio Yamamoto, ..., Atsushi Imai (2010). Gynecological Endocrinology. 2010 Mar 18
• In this study, the Human Tissue-type Plasminogen Activator (tPA) AssayMax ELISA Kit from Assaypro was utilized to quantitatively assess the levels of tissue-type plasminogen activator …

Neuroserpin, a thrombolytic serine protease inhibitor (serpin), blocks transplant vasculopathy with associated modification of T-helper cell subsets

• https://pubmed.ncbi.nlm.nih.gov/20135065/
• Ganesh Munuswamy-Ramanujam, Erbin Dai, ..., Alexandra Lucas (2010). Thrombosis and haemostasis. 2010 Jan 01
• In the study, the Human Tissue-type Plasminogen Activator (tPA) AssayMax ELISA Kit from Assaypro played a significant role in measuring tissue-type plasminogen activator levels. This a…

Prostaglandin E2 Acts via Multiple Receptors to Regulate Plasminogen-Dependent Proteolysis in the Primate Periovulatory Follicle

• https://pubmed.ncbi.nlm.nih.gov/18818294/
• Nune Markosyan, Diane M. Duffy (2010). pmc02630891. 2010 Jan 01
• After 3 h incubation, proteolytic zones were visible distant from the tissue section, indicating spontaneous degradation of milk casein. tPA and PAI-1 measurements in follicular fluid Follicular fluid levels of total tPA and total PAI-1 were determined using AssayMax Human tPA and AssayMax Human PAI-1 ELISA kits (AssayPro, St. Charles, MO) according to the kit instructions.

HMG-CoA reductase inhibitor lovastatin upregulates plasminogen activator production through RhoA-signaling in peritoneal cell line Met5A

• No Link Provided
• Noriko Suzuki, Atsushi Imai (2009). Gynecological Surgery. 2009 Dec 22
• mstat, Germany) and Sigma (St. Louis, MO, USA), respectively. C3 transferase was a product of Cytoskelton (Denver, CO, USA). Human tPA enzyme-linked immunosorbent assay (ELISA) kit was purchased from AssayPro (St. Charles, MO, USA). All other chemicals were of reagent grade. This study did not require approval of our institutional review board because it did not imply active involvement of patients

Hypertension and hemostatic/fibrinolytic balance disorders

• https://pubmed.ncbi.nlm.nih.gov/20003834/
• O Tabak, R Gelisgen, ..., Y Karter (2009). Clinical Investigative Medicine. 2009 Dec 01
• same batch). Plasma PAI–1, tPA, tPA/PAI–1 complex levels were measured by a quantitative sandwich enzyme immunoassay technique, using commercial assay kits, according to manufacturer’s instructions (Assaypro, Brooklyn, USA). Absorbance values were read in an ELISA plate reader and the concentration of samples was automatically calculated by software. Samples were run in duplicate, and the 2 measur

Elevation of fasting insulin and its association with cardiovascular disease risk in women with systemic lupus erythematosus.

• https://pubmed.ncbi.nlm.nih.gov/19037607/
• Tim K Tso, Wen-Nan Huang (2009). Rheumatology international. 2009 Sep 02
• In this study, the Human Tissue type Plasminogen Activator tPA AssayMax ELISA Kit played a vital role in measuring plasma levels of t-PA, enhancing the understanding of fibrinolytic fa…

Is Familial Mediterranean Fever a thrombotic disease or not?

• https://pubmed.ncbi.nlm.nih.gov/17436016/
• Atalay Demirel, Tiraje Celkan, ..., Inci Yıldız (2007). European journal of pediatrics. 2007 Apr 14
• In the study investigating Familial Mediterranean Fever (FMF), the Human Tissue-type Plasminogen Activator (tPA) AssayMax ELISA Kit played a significant role in demonstrating the alter…

Glucose-Based PD Solution, But Not Icodextrin-Based PD Solution, Induces Plasminogen Activator Inhibitor-1 and Tissue-Type Plasminogen Activator in Human Peritoneal Mesothelial Cells via ERK1/2

• https://pubmed.ncbi.nlm.nih.gov/17381529/
• Masahira Katsutani, Takafumi Ito (2007). Therapeutic Apheresis and Dialysis. 2007 Apr 01
• Abstract: Peritoneal dialysis (PD) solutions containing glucose are considered to cause peritoneal fibrosis. Plasminogen activator inhibitor-1 (PAI-1) and tissue-type plasminogen activator (t-PA) part…

The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1.

• https://pubmed.ncbi.nlm.nih.gov/17122062/
• Taku Nagai, Mina Ito, ..., Kiyofumi Yamada (2006). The Journal of neuroscience : the official…. 2006 Dec 15
• Measurement of tPA protein.Measurement of tPA protein.. The Assaymax human tPA ELISA kit (ET1001-1; AssayPro, Brooklyn, NY) was used for detecting mouse tPA protein (Mataga et al., 2004).. This assay uses a quantitative sandwich enzyme immunoassay technique: murine antibody specific for tPA ..

Lysophosphatidylcholine induces tPA gene expression through CRE-dependent mechanism

• https://pubmed.ncbi.nlm.nih.gov/15721275/
• Abdullah Md. Sheikh, Hiroshi Ochi, Junichi Masuda (2005). Biochemical and biophysical research commu…. 2005 Apr 01
• In the study investigating the effects of lysophosphatidylcholine (lysoPC) on tissue-type plasminogen activator (tPA) gene expression, the Human Tissue-type Plasminogen Activator (tPA)…

Experience-Dependent Pruning of Dendritic Spines in Visual Cortex by Tissue Plasminogen Activator

• https://pubmed.ncbi.nlm.nih.gov/15603745/
• Nobuko Mataga, Yoko Mizuguchi, Takao K. Hensch (2004). Neuron. 2004 Dec 01
• Abstract: Sensory experience physically rewires the brain in early postnatal life through unknown processes. Here, we identify a robust anatomical consequence of monocular deprivation (MD) in layer II…

Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects

• https://pubmed.ncbi.nlm.nih.gov/20018898/
• Kamala Kesavan, Judson Ratliff, ..., Douglas B Jacoby (undefined). pm20018898. undefined undefined undefined
• s were transferred to fresh tubes, snap frozen in liquid nitrogen, and stored at −80 °C. tPA levels and activity were measured using colorimetric enzyme-linked immunosorbent assay kits purchased from AssayPro as per the manufacturer's instructions. The activity is measured as the ability of tPA present in the supernatants to activate plasminogen in an indirect assay that measures the amount of plas