Human alpha-1-Antitrypsin (A1AT) ELISA Kit

$407.00

Catalog Number: EA5101-1

This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Product Size:96 Well Plate

Additional information

Format

Sandwich ELISA

Entrez Gene

5265

Components

Biotinylated Human alpha-1.pdf-Antitrypsin Antibody, Chromogen Substrate (1x), Human alpha-1-Antitrypsin Microplate, Human alpha-1-Antitrypsin Standard, MIX Diluent Concentrate (10x), Sealing Tapes, SP Conjugate (100x), Stop Solution (1x), Wash Buffer Concentrate (20x)

TIme

4 hours

Sensitivity

0.26 ng/ml

Range

0.391 – 25 ng/ml

Samples Type

CSF, Plasma, Saliva. Milk, Serum, Urine

Associated Disease

Cancer, Cardiovascular, Hypoxia

Species

Human

UniProt

P01009

Storage

Refer to component labels for details

Plex

1

Usage

For Research Use Only, Not To Be Used For Diagnostic Purposes

Documentation

Publications

Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.

Long-term expansion of functional mouse and human hepatocytes as 3D organoids

  • https://www.cell.com/cell/fulltext/S0092-8674(18)31505-8
  • H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias… - Cell, 2018 - cell.com
  • The mammalian liver possesses a remarkable regenerative ability. Two modes of damage response have been described: (1) The "oval cell" response emanates from the biliary tree …

SARS‐CoV‐2 infection results in upregulation of Plasminogen Activator Inhibitor‐1 and Neuroserpin in the lungs, and an increase in fibrinolysis inhibitors associated …

  • https://onlinelibrary.wiley.com/doi/abs/10.1002/jha2.654
  • KH Toomer, GF Gerber, Y Zhang, L Daou, M Tushek… - …, 2023 - Wiley Online Library
  • Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection results in coagulation activation although it is usually not associated with consumption coagulopathy. D‐…

Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

  • https://www.biorxiv.org/content/10.1101/2024.10.29.620824.abstract
  • AI Ardisasmita, IP Joore, N Levy, A Myszczyszyn… - bioRxiv, 2024 - biorxiv.org
  • Accurate liver disease modeling and drug toxicity testing still remain challenging as liver cells in vitro poorly resemble adult hepatocytes, as we previously demonstrated using whole …

* Kondo A et al. (2021) Measuring serum prothrombin in patients treated with warfarin or direct oral anticoagulants. Clin Chim Acta. 523:224-230.

* Sekine K et al. (2020) Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media. Sci Rep. 10(1):17937.

* Schneeberger K et al. (2020) Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells.Hepatology. 72(1):257-270

* Zheng BN et al. (2019) Targeting PRMT5 activity inhibits the malignancy of hepatocellular carcinoma by promoting the transcription of HNF4alpha. Theranostics. 9(9):2606-2617.

* Zhang N et al. (2019) Enhanced secretion of human alpha1-antitrypsin expressed with a novel glycosylation module in tobacco BY-2 cell culture. Bioengineered 10(1):87-97.

* Hu H et al. (2018) Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids. Cell. 175(6):1591-1606.e19.

* Wormser U et al. (2016) Reduced levels of alpha-1-antitrypsin in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a novel approach for a potential treatment. J Neuroinflammation. 13(1):131.

* Huch M et al. (2015) Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver. Cell 160(1-2):299-312.

* Yang N et al. (2011) Urinary Glycoprotein Biomarker Discovery for Bladder Cancer Detection Using LC/MS-MS and Label-Free Quantification. Clin Cancer Res. 17(10): 3349-3359

* Wada H et al. (2011) alpha1-Antitrypsin low-density-lipoprotein serves as a marker of smoking-specific oxidative stress. J Atheroscler Thromb. 19(1):47-58.

* Goltsman I et al. (2011) Effects of Chronic Rosiglitazone Treatment on Renal Handling of Salt and Water in Rats With Volume-Overload Congestive Heart Failure. Circ Heart Fail. 4(3):345-54

* Funakoshi N et al. (2011) Comparison of Hepatic-like Cell Production from Human Embryonic Stem Cells and Adult Liver Progenitor Cells: CAR Transduction Activates a Battery of Detoxification Genes. Stem Cell Rev and Rep 7:518-531

* Dokai M et al. (2011) Local regulation of neutrophil elastase activity by endogenous alpha1-antitrypsin in lipopolysaccharide-primed hematological cells. Thrombosis Research 128(3):283-292

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