Human Apolipoprotein B (Apo B) ELISA Kit

$407.00

Catalog Number: EA7001-1

This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Product Size:96 Well Plate

Additional information

Format

Sandwich ELISA

Entrez Gene

338

Components

Biotinylated Human Apolipoprotein B Antibody, Chromogen Substrate (1x), EIA Diluent Concentrate (10x), Human Apolipoprotein B Microplate, Human Apolipoprotein B Standard, Sealing Tapes, SP Conjugate (100x), Stop Solution (1x), Wash Buffer Concentrate (20x)

TIme

4 hours

Sensitivity

1.2 ng/ml

Range

3.906 – 250 ng/ml

Samples Type

CSF, Plasma, Serum

Associated Disease

Cancer, Cardiovascular, Heart Disease

Species

Human

UniProt

P04114

Storage

Refer to component labels for details

Plex

1

Usage

For Research Use Only, Not To Be Used For Diagnostic Purposes

Documentation

Publications (32 results)

Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.

PCSK9 inhibition with alirocumab reduces lipoprotein (a) levels in nonhuman primates by lowering apolipoprotein (a) production rate

  • https://portlandpress.com/clinsci/article-abstract/132/10/1075/77785
  • M Croyal, TTT Tran, RH Blanchard, JC Le Bail… - Clinical …, 2018 - portlandpress.com
  • Therapeutic antibodies targeting proprotein convertase subtilisin kexin type 9 (PCSK9) (eg alirocumab) lower low-density lipoprotein cholesterol (LDL-C) and lipoprotein (a) [Lp(a)] …

Lipoprotein (a) cellular uptake ex vivo and hepatic capture in vivo is insensitive to PCSK9 inhibition with alirocumab

  • https://www.jacc.org/doi/abs/10.1016/j.jacbts.2020.03.008
  • K Chemello, S Beeské, TT Trang Tran… - Basic to Translational …, 2020 - jacc.org
  • Lipoprotein(a) (Lp[a]) is the most common genetically inherited risk factor for cardiovascular disease. Many aspects of Lp(a) metabolism remain unknown. We assessed the uptake of …

Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease

  • https://link.springer.com/article/10.1186/1471-2164-15-904
  • P Dowling, C Hayes, KR Ting, A Hameed, J Meiller… - BMC genomics, 2014 - Springer
  • Background Bone destruction is a feature of multiple myeloma, characterised by osteolytic bone destruction due to increased osteoclast activity and suppressed or absent osteoblast …

Assessment of oxLDL, anti-oxLDL antibodies and lipoprotein-associated phospholipase A2 as cardiovascular risk markers in obese adolescents with and …

COX-2 Induction Suppresses Endothelial Inflammation Elicited by Lipoproteins and Low Shear Stress

Evaluation of serum high molecular weight adiponectin and lipid profiles in predicting the risk of coronary artery disease among CAD patients

  • no link
  • M Chitra Devi, M Chandra Sekhar, P Sivasubramaniam - www. biomedicineonline …, 2016
  • no snippet

* Kondratieva LV et al. (2021) Clinical Importance of Leptin with systemic lupus erythematosus. Modern Rheumatology. 15(6):61-66.

* Grover A et al. (2020) Self-reported Morisky Eight-item Medication Adherence Scale for Statins Concords with the Pill Count Method and Correlates with Serum Lipid Profile Parameters and Serum HMGCoA Reductase Levels. Cureus.12(1):e6542.

* Chemello K et al. (2020) Lipoprotein (a) cellular uptake ex vivo and hepatic capture in vivo is insensitive to PCSK9 inhibition with alirocumab. JACC Basic Transl Sci. 5(6):549-557.

* Shi L et al. (2018) Cardiovascular Effects of Cyclical Dietary Vitamin C Withdrawal in Mice Deficient in Internal Synthesis Vitamin C and producing human lipoprotein (a): Gulo(-/-); Lp(a)+. Int J Cardiovasc Res 7:6

* EI-Tamalawy MM et al. (2018) Effect of combination therapy of ezetimibe and atorvastatin on remnant lipoprotein versus double atorvastatin dose in Egyptian diabetic patients. J Clin Pharmacol. 58(1):34-41.

* Omar NN et al. (2017) Assessment of oxLDL, anti-oxLDL antibodies and lipoprotein-associated phospholipase A2 as cardiovascular risk markers in obese adolescents with and without T1DM. Bulletin of Faculty of Pharmacy, Cairo University. 55(2): 325-331.

* Limareva LV et al. (2017) Assessment of the relationship between markers of inflammation, adipokines and lipid metabolism parameters in overweight and obese individuals.

* Gulati G et al. (2017) Prospective validation of a novel renal activity index of lupus nephritis. Lupus. 26(9):927-936.

* Grover A et al. (2017) Correlation of compliance to statin therapy with lipid profile and serum HMGCoA reductase levels in dyslipidemic patients. Indian Heart J. 69(1):6-10.

* Villard EF et al. (2016) PCSK9 Modulates the Secretion But Not the Cellular Uptake of Lipoprotein(a) Ex Vivo: An Effect Blunted by Alirocumab. JACC Basic Transl Sci. 1 (6) 419-427.

* Turker Y et al.(2016) High sensitive CRP and sICAM-1 can predict Major Adverse Cardiovascular Events: MELEN Study: A Large Turkish Population Based Study. Konuralp Tip Dergisi 2016;8(1):14-22

* Rath MW et al. (2016) Transgenic mouse expressing human lipoprotein (a) with disabled vitamin c gene and its use as a disease treatment model Patent application: WO2016057050 A1, PCT/US2014/060195

* Huang HC et al. (2016) Hypolipidaemic function of Hsian-tsao tea (Mesona procumbens Hemsl.): Working mechanisms and active components. J. Functional Foods. 26:217-227.

* Cha J et al. (2016) Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice. Int J Oncol. 49(3):895-902. Epub 2016 Jul 1.

* Wu T et al. (2015) The effects of Zanthoxylum bungeanum extract on lipid metabolism induced by sterols. J Pharmacol Sci. 127(3):251-9. doi: 10.1016/j.jphs.2014.12.002. Epub 2014 Dec 15

* Rath MW et al. (2015) Transgenic mouse expressing human apo(a) and human apo(B-100) with disabled vitamin C gene produces human Lp(a).United States Patent Application 20150074837

* Millar JS et al. (2015) Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects. J Clin Invest. 125(6):2510-22

* Cha J et al. (2015) Hypoascorbemia induces atherosclerosis and vascular deposition of lipoprotein(a) in transgenic mice. Am J Cardiovasc Dis. 5(1):53-62

* Dowling P et al. (2014) Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease. BMC Genomics. 2014 Oct 17;15:904. doi: 10.1186/1471-2164-15-904

* Wu T et al. (2012) Extracts of Zanthoxylum bungeanum regulate cholesterol accumulation induced by sterols and LPS in vitro and in vivo. J. Chi. Pharm. Sciences. 21:582-590.

* Krysiak R et al. (2012) The effect of ezetimibe and simvastatin on hemostasis in patients with isolated hypercholesterolemia. Fundam Clin Pharmacol. 26(3):424-31.

* Maillard P et al. (2011) Lipoprotein Lipase Inhibits Hepatitis C Virus (HCV) Infection by Blocking Virus Cell Entry. PLoS One. 6(10):e26637.

* Akanji AO et al. (2011) Determinants of blood levels of some thrombogenic biomarkers in healthy Arab adolescent subjects. Clin Chem Lab Med. 49(10):1681-90

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