Human Complement Factor B

$90.00

Catalog Number: PHC2541

Product Size: 20 ug

Additional information

Entrez Gene

629

Associated Disease

Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

Species

Human

UniProt

P00751

Protein Detail Express

CFB, 26-259aa, Human, His tag, E.coli

Purity

>90% by SDS-PAGE

Presentation

Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

MW

28.4 kDa (257aa)

Storage

-60°C or below

Protein Sequence

MGSSHHHHHH SSGLVPRGSQ SHMTPWSLAR PQGSCSLEGV EIKGGSFRLL QEGQALEYVC PSGFYPYPVQ TRTCRSTGSW STLKTQDQKT VRKAECRAIH CPRPHDFENG EYWPRSPYYN VSDEISFHCY DGYTLRGSAN RTCQVNGRWS GQTAICDNGA GYCSNPGIPI GTRKVGSQYR L

Documentation

    Publications (2 results)

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    Unraveling the molecular mechanisms underlying complement dysregulation by nephritic factors in C3G and IC-MPGN

    • https://www.frontiersin.org/articles/10.3389/fimmu.2018.02329/full
    • R Donadelli, P Pulieri, R Piras, P Iatropoulos… - Frontiers in …, 2018 - frontiersin.org
    • Membranoproliferative glomerulonephritis (MPGN) was recently classified as C3 glomerulopathies (C3G), and immune-complex (IC) mediated MPGN. Dysregulation of the complement …

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