Human GAPDH

$90.00

Catalog Number: PHG0801

Product Size: 20 ug

Catalog Number. PHG0801 Categories: , Tags: ,

Additional information

Entrez Gene

5216

Associated Disease

Apoptosis, Enzymes & Proteases, Metabolism, Proteases & Inhibitors

Species

Human

UniProt

P04406

Protein Detail Express

GAPDH, 1-335 aa, Human, E. coli

Purity

> 95% by SDS – PAGE

Presentation

Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM EDTA, 1mM DTT, 20% glycerol

MW

36 kDa (335aa) confirmed by MALDI-TOF

Storage

-60°C or below

Protein Sequence

MGKVKVGVNG FGRIGRLVTR AAFNSGKVDI VAINDPFIDL NYMVYMFQYD STHGKFHGTV KAENGKLVIN GNPITIFQER DPSKIKWGDA GAEYVVESTG VFTTMEKAGA HLQGGAKRVI ISAPSADAPM FVMGVNHEKY DNSLKIISNA SCTTNCLAPL AKVIHDNFGI VEGLMTTVHA I

Documentation

    Publications (25 results)

    Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.

    Promotion of Hypercoagulability in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis by C5a‐Induced Tissue Factor–Expressing Microparticles and …

    Inhibition of SUMOylation promotes remyelination and reduces IL-17 mediated autoimmune inflammation: Novel approach toward treatment of inflammatory CNS …

    • https://www.sciencedirect.com/science/article/pii/S0165572823002059
    • KW Kim, Å Ljunggren-Rose, P Matta, S Toki… - Journal of …, 2023 - Elsevier
    • Small ubiquitin like modifiers (SUMO) are reversible posttranslational modifiers of intracellular proteins. In the CNS, expression of myelin genes is regulated by state of SUMOylation of …

    Identification of hepatocyte-primed cholangiocytes in the homeostatic liver by in vivo lentiviral gene transfer to mice and non-human primates

    Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation

    Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants

    • https://www.nature.com/articles/srep22889
    • B Molins, P Fuentes-Prior, A Adán, R Antón… - Scientific reports, 2016 - nature.com
    • … Human GAPDH was used as endogenous control. Quantitative real-time PCR was performed on an ABI PRISM 7000 Detection System. The comparative CT method was used to …

    Targeting V-ATPase in primary human monocytes by archazolid potently represses the classical secretion of cytokines due to accumulation at the endoplasmic …

    • https://www.sciencedirect.com/science/article/pii/S0006295214004493
    • O Scherer, H Steinmetz, C Kaether, C Weinigel… - Biochemical …, 2014 - Elsevier
    • The macrolide archazolid inhibits vacuolar-type H(+)-ATPase (V-ATPase), a proton-translocating enzyme involved in protein transport and pH regulation of cell organelles, and potently …

    Everolimus combined with 5-aza-2-deoxycytidine generated potent anti-tumor effects on ovarian clear cell cancer stem-like/spheroid cells by inhibiting the COL6A3 …

    • https://pmc.ncbi.nlm.nih.gov/articles/PMC9077075/
    • CM Ho, FK Lee, TL Yen, SH Huang… - American journal of …, 2022 - pmc.ncbi.nlm.nih.gov
    • Ovarian clear cell cancer stem-like/spheroid cells (OCCCSCs) were associated with recurrence, metastasis, and chemoresistance in ovarian clear cell carcinoma (OCCC). We …

    Entry and disposition of Zika virus immune complexes in a tissue culture model of the maternal-fetal interface

    • https://www.mdpi.com/2076-393X/9/2/145
    • Y Xu, Y He, S Momben-Abolfath, N Eller, M Norton… - Vaccines, 2021 - mdpi.com
    • Zika virus (ZIKV) infections have been associated with an increased incidence of severe microcephaly and other neurodevelopmental disorders in newborn babies. Passive …

    Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene

    • https://pmc.ncbi.nlm.nih.gov/articles/PMC6857051/
    • R Zhao, G Ali, J Chang, S Komatsu, Y Tsukasaki… - …, 2019 - pmc.ncbi.nlm.nih.gov
    • Lung epithelial sodium channel (ENaC) encoded by Scnn1 genes is essential for maintaining transepithelial salt and fluid homeostasis in the airway and the lung. Compared to α, β, …

    Angiotensin II promotes the anticoagulant effects of rivaroxaban via angiotensin type 2 receptor signaling in mice

    • https://www.nature.com/articles/s41598-017-00473-5
    • D Yang, J Shao, R Hu, H Chen, P Xie, C Liu - Scientific Reports, 2017 - nature.com
    • Rivaroxaban is an oral direct factor Xa inhibitor approved for the treatment of stroke and systemic thromboembolism in patients with non-valvular atrial fibrillation. Despite its efficacy, …

    Aggregated low density lipoprotein induce impairment of the cytoskeleton dynamics through UPA/UPAR in human VSMC

    Autologous NeoHep derived from chronic hepatitis B virus patients' blood monocytes by upregulation of c-MET signaling

    • https://academic.oup.com/stcltm/article-abstract/6/1/174/6404695
    • J Bhattacharjee, B Das, D Sharma… - Stem Cells …, 2017 - academic.oup.com
    • In view of the escalating need for autologous cell-based therapy for treatment of liver diseases, a novel candidate has been explored in the present study. The monocytes isolated from …

    Aggregated low‐density lipoprotein induce impairment of the cytoskeleton dynamics through urokinase‐type plasminogen activator/urokinase‐type …

    • https://www.sciencedirect.com/science/article/pii/S1538783622065151
    • R Lugano, E Pena, L Badimon, T Padro - Journal of Thrombosis and …, 2012 - Elsevier
    • Background: Urokinase‐type plasminogen activator (UPA) regulates vascular smooth muscle cell (VSMC) functions relevant in vascular remodeling by facilitating proteolysis at the cell …

    Autologous NeoHep derived from chronic HBV patient's blood monocytes by upregulation of cMET signalling

    Alternative C3 complement system: lipids and atherosclerosis

    • https://www.mdpi.com/1422-0067/22/10/5122
    • M Garcia-Arguinzonis, E Diaz-Riera, E Peña… - International journal of …, 2021 - mdpi.com
    • Familial hypercholesterolemia (FH) is increasingly associated with inflammation, a phenotype that persists despite treatment with lipid lowering therapies. The alternative C3 …

    Fabrication of microchannel networks in multicellular spheroids

    Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants

    • https://diposit.ub.edu/dspace/handle/2445/112425
    • B Molins Monteys, P Fuentes Prior… - … 6, num. 22889, p. 1-12, 2016 - diposit.ub.edu
    • … Human GAPDH was used as endogenous control. Quantitative real-time PCR was performed on an ABI PRISM 7000 Detection System. The comparative CT method was used to …

    Identification of Hepatocyte-Primed Biliary Epithelial Cells in the Homeostatic Liver by in vivo Lentiviral Gene Transfer to Mice and Non-Human Primates

    • https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4452657
    • M Milani, F Starinieri, S Beretta, A Fabiano, T Plati… - papers.ssrn.com
    • Liver regeneration is supported by hepatocytes and, in certain conditions, biliary epithelial cells (BEC). BEC are bipotent stem cells, able to form organoids in culture and engraft in …

    CRISPR–Cas3-based editing for targeted deletions in a mouse model of transthyretin amyloidosis

    • https://www.nature.com/articles/s41587-025-02949-6
    • S Ishida, Y Sato, K Chosa, E Ezawa, Y Yamauchi… - Nature …, 2026 - nature.com
    • … (Ttr) expression was normalized to that for the control gene, mouse B2m or human GAPDH. … , and human prealbumin (TTR) AssayMax ELISA kit (AssayPro, EP3010-1) for Ttr hV30orf/…

    THE UNIVERSITY OF HULL

    Restraint stress exacerbates cardiac and adipose tissue pathology via β-adrenergic signaling in rats with metabolic syndrome

    Target identification and probe development for pancreatic neuroendocrine tumors

    G protein-coupled peptide receptors as molecular targets in neuroendocrine tumors

    Low density lipoproteins, vascular smooth muscle cell function and vascular remodeling

    • https://www.tdx.cat/handle/10803/283471
    • R Lugano - 2014 - tdx.cat
    • High levels of circulating low-density lipoproteins (LDL) are one of the major cardiovascular risk factors. Hypercholesterolemia induces endothelial dysfunction and chronic intimal …

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