Name: Human Kallikrein
SKU: PK20031
Availability: InStock

Additional information

Entrez Gene	3816
Associated Disease	Cancer
Species	Human
UniProt	P06870
Protein Detail Express	Kallikrein purified from human plasma
Purity	>96% by SDS-PAGE
Presentation	Lyophilized from 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3 with 5% Treharose
Storage	-20°C or below

Documentation

Publications (5 results)

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Diabetes‐induced upregulation of kallistatin levels exacerbates diabetic nephropathy via RAS activation

https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.201903149R
Y Yang, X He, R Cheng, Q Chen, C Shan… - The FASEB …, 2020 - Wiley Online Library
Kallistatin is an inhibitor of tissue kallikrein and also inhibits the Wnt pathway. Its role in diabetic nephropathy (DN) is uncertain. Here we reported that serum kallistatin levels were …

Design, synthesis, and biological evaluation of substituted oxopyridine derivatives as selective FXIa inhibitors

https://pubs.rsc.org/en/content/articlehtml/2025/md/d4md01013b
Y Wang, S Yan, J Yuan, X Meng, P Liu… - RSC Medicinal …, 2025 - pubs.rsc.org
… Then, 3 μL tested solution or DMSO (blank control group), 18 μL buffer (20 mM Tris-HCl pH 7.8, 100 mM NaCl solution), and 3 μL human kallikrein protein (58 μM, ASSAYPRO, PK20031…

* Zheng YZ et al. (2021) WPK5, a Novel Kunitz-Type Peptide from the Leech Whitmania pigra Inhibiting Factor XIa, and Its Loop-Replaced Mutant to Improve Potency. Biomedicines. 9(12):1745.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698482/pdf/biomedicines-09-01745.pdf

* Jia Z et al. (2021) DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of Deinagkistrodon acutus Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor XIa. Pharmaceuticals (Basel). 14(10):966.