Human Leptin

$80.00

Catalog Number: PHL33002

Product Size: 20 ug

Catalog Number. PHL33002 Categories: , Tag:

Additional information

Entrez Gene

3952

Associated Disease

Diabetes

Species

Human

UniProt

P41159

Protein Detail Express

Leptin, Human, E.coli

Purity

> 95% by SDS – PAGE

Presentation

Liquid in Phosphate Buffered Saline (pH 7.4)

MW

16 kDa (147 aa), confirmed by MALDI-TOF

Storage

-60°C or below

Protein Sequence

MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHVLAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC

Documentation

    Publications (57 results)

    Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.

    Leptin and leptin receptor gene polymorphisms and their association with plasma leptin levels and obesity in a multi-ethnic Malaysian suburban population

    • https://link.springer.com/article/10.1186/1880-6805-33-15
    • SH Fan, YH Say - Journal of physiological anthropology, 2014 - Springer
    • Background This study was to investigate the prevalence of single nucleotide polymorphisms (SNPs) in leptin gene LEP (A19G and G2548A) and leptin receptor gene LEPR (K109R …

    Severe early-onset obesity due to bioinactive leptin caused by a p. N103K mutation in the leptin gene

    • https://academic.oup.com/jcem/article-abstract/100/9/3227/2836015
    • M Wabitsch, JB Funcke… - The Journal of …, 2015 - academic.oup.com
    • … Treatment with sc recombinant human leptin led to rapid improvement of eating behavior … -assay CV of 6.0–6.9%; and from Assaypro, with a detection limit of approximately 0.12 ng/mL, …

    Leptin levels in vitreous fluids of patients with diabetic retinopathy

    • https://jrmi.pk/article/view/5
    • AAS Bukhari, N Parveen, Q Khan, K Khan - Journal of Rehman Medical …, 2015 - jrmi.pk
    • … The enzyme immunoassay test followed a typical two-step capture or “sandwich” type assay by using AssayMax Human Leptin EliSA Kit (Assaypro, Belgium). Data were analyzed using …

    Clinical significance of serum leptin level in patients with gastric cancer

    • https://link.springer.com/article/10.1684/ecn.2018.0408
    • F Tas, S Karabulut, K Erturk, D Duranyildiz - European Cytokine Network, 2018 - Springer
    • Leptin may support the proliferation and hinder the apoptosis of tumor cells. Although leptin expression has been studied in several human tumors, its potential clinical significance …

    Serum leptin, adiponectin, resistin and ghrelin levels in psoriatic patients treated with cyclosporin

    Evaluation of body weight, insulin resistance, leptin and adiponectin levels in premenopausal women with hyperprolactinemia

    • https://link.springer.com/article/10.1007/s12020-013-9931-0
    • A Atmaca, B Bilgici, GC Ecemis, OK Tuncel - Endocrine, 2013 - Springer
    • The effects of hyperprolactinemia on metabolic parameters are not clear and a few data evaluating adiponectin levels in prolactinoma and idiopathic hyperprolactinemia exist. The aim …

    LEVELS OF SERUM INTERLEUKIN IL-6 IN PATIENTS WITH ADVANCED DIABETIC RETINOPATHY

    • https://jrmi.pk/article/view/3
    • AAS Bukhari, N Parveen, Q Khan, K Khan - Journal of Rehman Medical …, 2015 - jrmi.pk
    • … The enzyme immunoassay test followed a typical two-step capture or “sandwich” type assay by using AssayMax Human Leptin EliSA Kit (Assaypro, Belgium). Data were analyzed using …

    In vitro fertilization, levels of pro-inflammatory factors and lipid peroxidation

    • https://pmc.ncbi.nlm.nih.gov/articles/PMC4671383/
    • F Yildizfer, O Donma, M Yen, O Ekmekci… - … Journal of Fertility & …, 2015 - pmc.ncbi.nlm.nih.gov
    • Background Infertility is a problem concerning 10-15% of the individuals in the fertile period. This study investigated effects of proinflammatory factors as well as lipid hydroperoxides (…

    The role of adenovirus 36 as a risk factor in obesity: the first clinical study made in the fatty tissues of adults in Turkey

    • https://www.sciencedirect.com/science/article/pii/S0882401015000273
    • S Ergin, E Altan, O Pilanci, S Sirekbasan, O Cortuk… - Microbial …, 2015 - Elsevier
    • Obesity which developes due to multifactorial reasons, was associated recently with human Adenovirus-36 (Ad-36). The aim of this study was to investigate the prevalence of Ad-36 …

    Esat Imal A, Cagil E, Mengi M, Ekmekci H, Sahmay S, Nalbantoglu B, Donma MM

    • https://www.academia.edu/download/103743419/107320150302.pdf
    • F Yildizfer - vitro fertilization, levels of pro-inflammatory factors and …, 2015 - academia.edu
    • … CRP is a negative regulator of functions of human leptin (10). Resistin is synthesized mostly by inflammatory cells such as macrophages and correlated with TNF-α (9). Resistin levels …

    Tomato juice supplementation in young women reduces inflammatory adipokine levels independently of body fat reduction

    Leptin as an important link between obesity and cardiovascular risk factors in men with acute myocardial infarction

    Circulating levels of adiponectin, leptin, fetuin-A and retinol-binding protein in patients with tuberculosis: markers of metabolism and inflammation

    Association of polymorphism in adiponectin (+ 45 T/G) and leptin (–2548 G/A) genes with type 2 diabetes mellitus in male Egyptians

    Association of vitamin D supplementation with serum leptin and metabolic parameters in Egyptian patients with non-alcoholic steatohepatitis: a prospective study

    The effects of 17β-estradiol plus drospirenone on anthropometric and biochemical measures of adiposity in menopausal women

    • https://link.springer.com/article/10.1007/s00404-012-2437-9
    • M Karakus, R Gelisgen, A Topcuoglu, O Guralp… - Archives of gynecology …, 2012 - Springer
    • Purpose To assess whether there are changes on anthropometric and biochemical measures of adiposity in pre- and postmenopausal women and in the latter before and after 6 …

    Leptin and adiponectin, but not IL18, are related with insulin resistance in treated HIV-1-infected patients with lipodystrophy

    Leptin: adiponectin ratio is an independent predictor of intima media thickness of the common carotid artery

    • https://www.ahajournals.org/doi/abs/10.1161/strokeaha.107.485540
    • GD Norata, S Raselli, L Grigore, K Garlaschelli… - Stroke, 2007 - ahajournals.org
    • … Circulating concentrations of total leptin were measured using a commercial radioimmunoassay kit for human leptin (Linco Research Inc, St. Louis, Mo) and plasma adiponectin levels (…

    Interrelationship between bone turnover markers, calciotropic hormones and leptin in obese Saudi children.

    • https://www.europeanreview.org/wp/wp-content/uploads/4332-4343.pdf
    • LM Saber, HNF Mahran, HH Baghdadi… - European Review for …, 2015 - europeanreview.org
    • … The ASSAYPRO Leptin ELISA is an enzyme immunoassay for the measurement of leptin in serum and plasma. By determining this bone resorption marker, Collagen type I fragments β-…

    Serum leptin level and waist-to-hip ratio (WHR) predict the overall survival of metastatic breast cancer (MBC) patients treated with aromatase inhibitors (AIs)

    • https://link.springer.com/article/10.1007/s12282-011-0322-1
    • M Artac, H Bozcuk, A Kıyıcı, OO Eren, MC Boruban… - Breast Cancer, 2013 - Springer
    • … Leptin determinations were performed by the ELISA technique using commercially available kits (AssayMax Human Leptin, Cat.No:EL2001-1; AssayPro, USA). Estradiol (lot no: …

    Effect of uvulopalatopharyngoplasty on leptin and endothelial function in sleep apnea

    • https://journals.sagepub.com/doi/abs/10.1177/0003489414521385
    • CC Lin, YP Wang, KS Lee, SF Liaw… - Annals of Otology …, 2014 - journals.sagepub.com
    • … The serum leptin concentration was measured by enzyme-linked immunosorbent assay with the AssayMax Human Leptin ELISA Kit (AssayPro, St Charles, Missouri). The samples were …

    Correlation of C1q/TNF-related protein-3 with cardiac autonomic tone and metabolic parameters in obesity

    • https://pmc.ncbi.nlm.nih.gov/articles/PMC6628617/
    • NB Jain, A Yadav, N Shankar… - International Journal of …, 2019 - pmc.ncbi.nlm.nih.gov
    • … ELISA research kit by Assaypro LLC, designed … human leptin ELISA kit from Boster Biological Technology Co., Ltd. The standard product used in this kit was recombinant human leptin …

    Fructose induced leptin dysfunction and improvement by quercetin and rutin in rats

    Ventricular hypertrophy and cavity dilatation in relation to body mass index in women with uncomplicated obesity

    • https://heart.bmj.com/content/97/3/203.short
    • OJ Rider, SE Petersen, JM Francis, MK Ali… - Heart, 2011 - heart.bmj.com
    • Objective The traditionally accepted mechanism for ventricular adaptation to obesity suggests that cavity dilatation in response to increased blood volume and elevated filling pressure …

    Adipokines, psoriasis, systemic inflammation, and endothelial dysfunction

    • https://onlinelibrary.wiley.com/doi/abs/10.1111/ijd.13699
    • M Lynch, T Ahern, CM Sweeney… - International journal …, 2017 - Wiley Online Library
    • … In one study of 109 patients with psoriasis and 125 healthy controls, the frequencies of a common polymorphism in the promoter of the human leptin gene (G-2548A, Ch7q31.3) were …

    Circulating and adipose tissue gene expression of zinc-α2-glycoprotein in obesity: its relationship with adipokine and lipolytic gene markers in subcutaneous and …

    • https://academic.oup.com/jcem/article-abstract/94/12/5062/2597285
    • V Ceperuelo-Mallafré, S Naf, X Escoté… - The Journal of …, 2009 - academic.oup.com
    • Context: Zinc-α2-glycoprotein (ZAG) is a soluble protein similar to the class I major histocompatibility complex heavy chain, which has been implicated in lipid catabolism. We …

    Comparison of Maternal Serum Adiponectin and Leptin Measurements in Screening and Diagnosis of Gestational Diabetes Mellitus

    • https://perinataljournal.com/content/pdf/v16i3/Article3.pdf
    • DK Gül, Ö Gelen - Instructions for the Authors - perinataljournal.com
    • … by a kit which is based on ELISA (Human adiponectin assaypro catalog no: EA2500-1). Adiponectin … Human leptin: the hormone of adipose tissue. Eur J Endocrinol 1997; 136: 461–4. 5. …

    A study of fatty acid binding protein 4 in HIV‐1 infection and in combination antiretroviral therapy‐related metabolic disturbances and lipodystrophy

    Serum leptin, adiponectin, resistin, visfatin and inflammatory cytokines in normal weight and obese women with normal pregnancy and with preeclampsia

    • no link
    • AF Noureldeen, SY Qusti, M Al-seeni - Life science journal, 2014 - Citeseer
    • no snippet

    Obesity and CRP, adiponectin, leptin, and lipid profile in Saudi Arabian adolescent females

    Role of central leptin signaling in the starvation-induced alteration of B-cell development

    • https://www.jneurosci.org/content/31/23/8373.short
    • M Tanaka, T Suganami, M Kim-Saijo, C Toda… - Journal of …, 2011 - jneurosci.org
    • Nutritional deprivation or malnutrition suppresses immune function in humans and animals, thereby conferring higher susceptibility to infectious diseases. Indeed, nutritional deprivation …

    Evaluation of Adenovirus-36 (Ad-36) antibody seropositivity and adipokine levels in obese children

    Exploring Human Biological Variation in Metabolic Hormones

    Evaluation of Adenovirus-36 (Ad-36) antibody seropositivity and adipokine levels in obese children

    Interrelationships between obesity and bone markers in post-menopausal women with either obesity or osteoporosis

    • https://www.sciencedirect.com/science/article/pii/S1878764914001521
    • A Doventas, IM Bolayirli, S Incir, H Yavuzer… - European Geriatric …, 2015 - Elsevier
    • Purpose Obesity and bone metabolism are interrelated. The aim of this study is to investigate the relationship between obesity and bone markers, leptin and insulin resistance in post-…

    Genetic, dietary, and non-dietary risk factors of obesity among preparatory-year female students at Taibah University, Saudi Arabia

    • https://www.sciencedirect.com/science/article/pii/S1658365516300401
    • DE El Nashar, KM Alananbeh, N Al Hassan - Journal of Taibah University …, 2017 - Elsevier
    • Genetic factors have a strong influence on obesity and are associated with body mass index (BMI). No study has investigated the relationships between glucose, the fat mass and …

    Identification of heat stress-susceptible and-tolerant phenotypes in goats in semiarid tropics

    • https://connectsci.au/an/article-abstract/58/7/1349/19563
    • PK Rout, R Kaushik, N Ramachandran… - Animal Production …, 2018 - connectsci.au
    • The production performance of livestock is influenced by short-term variation in weather pattern. Goat adapts to varied ecological conditions and maintains productivity; however, wide …

    Роль адипокинов в прогрессировании колоректального рака

    Siklosporin tedavisi alan psoriasisli hastalarda serum leptin, adiponektin, resistin ve ghrelin düzeyleri

    • no link
    • M Yüksel - 2010 - Necmettin Erbakan Üniversitesi …
    • no snippet

    Role of poly (ADP-ribose) polymerase-1 and cytokines in acute renal injury in elderly Chinese patients with diabetes mellitus

    • https://www.tandfonline.com/doi/abs/10.2147/CIA.S142102
    • L Cao, Y Liu, L Zhang, Y Wei - Clinical Interventions in Aging, 2017 - Taylor & Francis
    • … kits (Assaypro Human IL-6, IL-1β and TNF-α) coated with antibodies specific to human leptin and adiponectin antibodies, according to the manufacturer’s protocols (St Charles). …

    Effect of Fasting Therapy and Low-Calorie Diet on Anthropometric and Serum Lipids in Obese Females

    Evaluation of oral antiretroviral drugs in mice with metabolic and neurologic complications

    • https://www.frontiersin.org/articles/10.3389/fphar.2018.01004/full
    • FJ Tsai, MW Ho, CH Lai, CH Chou, JP Li… - Frontiers in …, 2018 - frontiersin.org
    • Antiretroviral (ART) drugs has previously been associated with lipodystrophic syndrome, metabolic consequences, and neuropsychiatric complications. ART drugs include three main …

    The probable role of insulin resistance and SIRT1 proteins in the Alzheimer's disease.

    Impact of serum adipokines on tumor mitotic and apoptotic activity in endometrial cancer

    • https://dergipark.org.tr/tr/doi/10.28982/josam.581498
    • A Özdemir, P Karlı, A Kökçü, M Kefeli - Journal of Surgery and …, 2019 - dergipark.org.tr
    • Aim: Endometrial cancer is the most common malignancy of female genital system. Obesity is one of the most important risk factors in endometrial cancer. Adipose tissue functions just …

    Dergi Kimliği

    • https://www.perinataldergi.com/Archive/Article/20080163003
    • A Göymen, M Öncül, O Güralp, C Şen, S Uludağ… - perinataldergi.com
    • … Serum Adiponektin Düzeyi Ölçümü: ELISA esasına dayalı kit (Human adiponectin assaypro catalog no: EA2500-1) ile ölçüldü. Adiponektin düzeyleri; µg/ml (mikrogram/ml) birimiyle …

    Effects of falciparum malaria on levels of selected biomarkers of cardiovascular disease risk in type 2 diabetics and non-diabetic controls

    • no link
    • S Acquah - 2013 - University of Cape Coast
    • no snippet

    EARLY METABOLIC AND HEPATIC EFFECTS OF PARTIAL LIPECTOMY IN OVARIECTOMIZED YOUNG RATS

    • no link
    • FA Mohamed, BMA El-Kafoury, NM Bahgat, AA Abd El… - Ain Shams Medical Journal, 2015
    • no snippet

    Association between obstructive sleep apnea severity and endothelial dysfunction in patients with type 2 diabetes

    • https://link.springer.com/article/10.1186/s12933-017-0521-y
    • V Bironneau, F Goupil, PH Ducluzeau… - Cardiovascular …, 2017 - Springer
    • Background Obstructive sleep apnea (OSA) and type 2 diabetes (T2D) are associated with endothelial dysfunction a main predictor of late cardiovascular (CV) events. Despite the high …

    Involvement of poly (ADP-ribose) polymerase-1 in Chinese patients with glioma: a potential target for effective patient care

    • https://journals.sagepub.com/doi/abs/10.5301/ijbm.5000267
    • J Ren, P Jia, H Feng, X Li, J Zhao… - … International Journal of …, 2018 - journals.sagepub.com
    • … kits (Assaypro Human IL-6, IL-1β and TNF-α) coated with antibodies specific to human leptin and adiponectin antibodies according to the manufacturer’s protocols (St. Charles). …

    Periton diyalizi hastalarında serum leptin düzeyinin inflamasyon belirteçleri ve karotis intima-medya kalınlığı üzerine etkileri

    ADIPOCYTOKINY A VYBRANÁ ZÁNĚTLIVÁ ONEMOCNĚNÍ: STUDIE KONTROL A PŘÍPADŮ

    • https://is.muni.cz/th/bzyic/DP_JJ_Archive.pdf
    • BJ Jánoš - is.muni.cz
    • Společným rysem multifaktoriálních chorob jako je refluxní ezofagitida (patřící do skupiny gastroezofageální refluxní choroby, GERD), astma, diabetes mellitus 2. typu (T2DM), chronická …

    Gestasyonel Diabetes Mellitus Tan› ve Taramas› nda Maternal Serum Adiponektin ile Leptin Ölçümlerinin Karfl› laflt› r› lmas›

    ЧУВСТВИТЕЛЬНОСТЬ К ИНСУЛИНУ У ПАЦИЕНТОВ С НЕАЛКОГОЛЬНОЙ ЖИРОВОЙ БОЛЕЗНЬЮ ПЕЧЕНИ И НАРУШЕНИЯМИ УГЛЕВОДНОГО …

    HARİKA ÖYKÜ DİN

    • https://nek.istanbul.edu.tr/ekos/TEZ/54176.pdf
    • UL ÜN - nek.istanbul.edu.tr
    • Yüksek lisans eğitimime başladığım günden itibaren engin bilgi ve tecrübelerini asistanları ile her zaman paylaşarak yetişmemde büyük emeği geçen ve tezimin her aşamasında …

    OBSTRÜKTİF UYKU APNE SENDROMU VE TEDAVİSİNİN LİPİD VE GLUKOZ METABOLİZMASI ÜZERİNE ETKİLERİNİN ARAŞTIRILMASI

    • https://nek.istanbul.edu.tr/ekos/TEZ/54823.pdf
    • DRD KARADENİZ, V İLBAY - nek.istanbul.edu.tr
    • … Leptin düzeyi ise Enzyme-Linked Immunosorbent Assay (ELISA)(sandwich) yöntemiyle Assaypro hazır kitleri ile çalışılmıştır. …

    果糖引起大鼠瘦素功能失调及槲皮素和芦丁的改善作用 (英文)

    • no link
    • 李建梅, 王闯, 胡庆华, 孔令东 - 中国天然药物: 英文版, 2008
    • no snippet

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