Publications (58 results)
Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.Human endothelial cells and fibroblasts express and produce the coagulation proteins necessary for thrombin generation
- https://www.nature.com/articles/s41598-021-01360-w
- CT Cohen, NA Turner, JL Moake - Scientific reports, 2021 - nature.com
- … The polyclonal sheep antibody made against human thrombin that was used in this study also detects FII. The fluorescent detection of FII/thrombin was low compared to …
Measuring serum prothrombin in patients treated with warfarin or direct oral anticoagulants
- https://www.sciencedirect.com/science/article/pii/S0009898121003430
- A Kondo, H Kondo, Y Nakagawa, H Kameyama, H Ito… - Clinica Chimica …, 2021 - Elsevier
- … ELISA kits for α2-macroglobulin (α2-M), α1-antitrypsin (α1-AT), antithrombin (AT), and thrombin-antithrombin complex (TAT) were from Assaypro. The ELISA kit for α-thrombin (Th) was …
Biological activity of a new recombinant human coagulation factor VIII and its efficacy in a small animal model
Potential value of human thrombomodulin and DAF expression for coagulation control in pig‐to‐human xenotransplantation
Production of cloned pigs expressing human thrombomodulin in endothelial cells
Functional difference between membrane-bound and soluble human thrombomodulin
Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions
Evaluation of thrombomodulin/thrombin activatable fibrinolysis inhibitor function in plasma using tissue-type plasminogen activator-induced plasma clot lysis …
- https://www.sciencedirect.com/science/article/pii/S2475037924001523
- T Urano, Y Sano, Y Suzuki, M Okada, H Sano… - Research and Practice …, 2024 - Elsevier
- Background Thrombin activatable fibrinolysis inhibitor (TAFI) is one of the most important physiological fibrinolysis inhibitors. Its inhibitory efficacy under physiological conditions …
Recurrent mutations in a SERPINC1 hotspot associate with venous thrombosis without apparent antithrombin deficiency
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5663607/
- W Zeng, B Hu, L Tang, YY You, M Toderici… - …, 2017 - pmc.ncbi.nlm.nih.gov
- … Conditioned medium of HEK-EBNA cells transfected with plasmids carrying different SERPINC1 mutations was incubated for 5 min with human thrombin and UFH. Antithrombin (AT) …
Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome
- https://www.tandfonline.com/doi/abs/10.1080/09513590802549874
- B Oral, B Mermi, M Dilek, G Alanoğlu… - Gynecological …, 2009 - Taylor & Francis
- … sandwich enzyme immunoassay technique (AssayMax Human Thrombin-AT Complexes ELISA Kit, AssayPro, MO). Intra- and inter-assay CV were 5.0% and 7.0% respectively. …
Pig tissue factor pathway inhibitor α fusion immunoglobulin inhibits pig tissue factor activity in human plasma moderately more efficiently than the human counterpart
- https://link.springer.com/article/10.1007/s10529-017-2405-3
- CY Choi, YH Kim, J Bae, SJ Lee, HK Kim, CG Park… - Biotechnology …, 2017 - Springer
- … activity kit according to the manufacturer’s instructions (Assaypro LLC, St. Charles, MO, USA). … Pig TF can generate human thrombin with increasing reaction time. Thrombin generation …
CRISPR/Cas and recombinase-based human-to-pig orthotopic gene exchange for xenotransplantation
Cell surface functionalization with heparin‐conjugated lipid to suppress blood activation
- https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202008167
- K Asawa, K Ishihara, KN Ekdahl… - Advanced Functional …, 2021 - Wiley Online Library
- … TAT was captured by a monoclonal antibody against human antithrombin, precoated onto a 96-well plate, and detected with biotinylated polyclonal antibody against human thrombin …
Mutational analysis of pig tissue factor pathway inhibitor α to increase anti-coagulation activity in pig-to-human xenotransplantation
- https://link.springer.com/article/10.1007/s10529-024-03505-z
- CH Lee, HJ Lee, SW Park, J Shin, SJ Kang, IB Park… - Biotechnology …, 2024 - Springer
- … 3a, human thrombin was generated in a bell-shaped pattern by pig TF in human plasma. The inhibitory effect of each pig TFPI-Ig was evaluated by two parameters, the peak thrombin …
FXa inhibition by rivaroxaban modifies mechanisms associated with the pathogenesis of human abdominal aortic aneurysms
- https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.13383
- G Moñux, JJ Zamorano‐León… - British Journal of …, 2017 - Wiley Online Library
- … Thrombin content in aortic explants was determined using a commercial ELISA kit (Human thrombin ELISA kit (Factor II), ab108909; Abcam, Cambridge, UK). The sensitivity of the assay …
New method to prepare autologous fibrin glue on demand
Efficacy of a new autologous platelet gel: In vitro study
- https://www.sid.ir/EN/VEWSSID/J_pdf/1001120120202.pdf
- TA HASHEMI, S Alizadeh, BM HEIDARI - 2012 - sid.ir
- … According to our finding, latency in the release of FGF is probably due to the low activity of autologous human thrombin. Kinetic experiments demonstrated that variations in GFs …
Linking complement activation, coagulation, and neutrophils in transplant-associated thrombotic microangiopathy
Heparin co‐factor II enhances cell motility and promotes metastasis in non‐small cell lung cancer
Effect of a Congolese herbal medicine used in sickle cell anemia on the expression of plasminogen activators in human coronary aortic endothelial cells culture
Analysis of thrombin‐antithrombin complex contents in plasma and hematoma fluid of hypertensive intracerebral hemorrhage patients after clot removal
The Roles of Plasma Proteins and Neutrophils in Melanoma Metastasis
Behçet's disease: new insight into the relationship between procoagulant state, endothelial activation/damage and disease activity
- https://link.springer.com/article/10.1186/1750-1172-8-81
- I Fernández-Bello, FJ López-Longo… - Orphanet journal of rare …, 2013 - Springer
- Background Behçet disease (BD) is associated with a prothrombotic state of unknown origin that may lead to life-threatening events. Calibrated Automated Thrombogram (CAT) and …
Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates
- https://www.sciencedirect.com/science/article/pii/S0304416513000044
- S Chen, G Li, N Wu, X Guo, N Liao, X Ye, D Liu… - … et Biophysica Acta (BBA …, 2013 - Elsevier
- BACKGROUND: The aim is to compare the structures, anticoagulant and antithrombotic activities of two fucosylated chondroitin sulfates isolated from sea cucumbers Isostichopus …
Effects of cigarette smoke exposure on clot dynamics and fibrin structure: an ex vivo investigation
- https://www.ahajournals.org/doi/abs/10.1161/ATVBAHA.109.195024
- RS Barua, F Sy, S Srikanth, G Huang… - … , and vascular biology, 2010 - ahajournals.org
- Objectives— The purpose of this study was to examine the effect of cigarette smoke exposure (CSE) on clot dynamics and fibrin architecture and to isolate the relative contribution of …
Characterization of Biomarkers of Thrombo-Inflammation in Patients with First-Diagnosed Atrial Fibrillation
- https://www.mdpi.com/1422-0067/25/7/4109
- J Friebel, M Wegner, L Blöbaum, PA Schencke… - International Journal of …, 2024 - mdpi.com
- Patients with first-diagnosed atrial fibrillation (FDAF) exhibit major adverse cardiovascular events (MACEs) during follow-up. Preclinical models have demonstrated that thrombo-…
Bioinspired affinity DNA polymers on nanoparticles for drug sequestration and detoxification
Acute cigarette smoke exposure reduces clot lysis--association between altered fibrin architecture and the response to t-PA
Efficacy of a New Autologus Platelet Gel: in Vitro Study
In vitro effects of detergent sclerosants on clot formation and fibrinolysis
Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin
- https://www.sciencedirect.com/science/article/pii/S2001037022000794
- D Nikitin, J Mican, M Toul, D Bednar, M Peskova… - Computational and …, 2022 - Elsevier
- Cardio- and cerebrovascular diseases are leading causes of death and disability, resulting in one of the highest socio-economic burdens of any disease type. The discovery of bacterial …
Autoantibodies Targeting AT1- and ETA-Receptors Link Endothelial Proliferation and Coagulation via Ets-1 Transcription Factor
- https://www.mdpi.com/1422-0067/23/1/244
- R Catar, M Herse-Naether, N Zhu, P Wagner… - International Journal of …, 2021 - mdpi.com
- Scleroderma renal crisis (SRC) is an acute life-threatening manifestation of systemic sclerosis (SSc) caused by obliterative vasculopathy and thrombotic microangiopathy. Evidence …
Blood coagulation and metabolic profiles in middle-aged male and female ob/ob mice
Thrombin based gelatin matrix and fibrin sealant mediated clot formation in the presence of clopidogrel
- https://link.springer.com/article/10.1186/1477-9560-12-10
- JF Dwyer, JA McCoy, Z Yang, M Husser, H Redl… - Thrombosis journal, 2014 - Springer
- Background Platelet inhibitors are commonly used to reduce the risk of atherothrombotic events. The aim of this study was to determine the impact of platelet inhibitors, specifically …
Anti‐phospholipid antibodies are elevated and functionally active in chronic rhinosinusitis with nasal polyps
- https://onlinelibrary.wiley.com/doi/abs/10.1111/cea.14120
- JG Eide, J Wu, WW Stevens, J Bai… - Clinical & …, 2022 - Wiley Online Library
- … Human thrombin-anti-thrombin (TaT) complex levels were tested using 1:4 dilution for all samples (Assaypro, St. Charles, MO), and anti-B2GP levels were determined using 1:4–1:50 for …
Endothelial dysfunction in obstructive sleep apnea patients
- https://link.springer.com/article/10.1007/S11325-021-02382-4
- M Harańczyk, M Konieczyńska, W Płazak - Sleep and Breathing, 2022 - Springer
- Purpose Obstructive sleep apnea syndrome (OSAS) is an independent risk factor for cardiovascular diseases. The aim of the study was to assess the influence of OSAS on endothelial …
Antibody-functionalized SERS tags with improved sensitivity
- https://pubs.rsc.org/en/content/articlehtml/2011/cc/c1cc12659h
- N Guarrotxena, GC Bazan - Chemical Communications, 2011 - pubs.rsc.org
- Protein detection at the femtomolar level can be achieved by using metallic nanoparticle assemblies that function as surface enhanced Raman spectroscopy reporters and that contain …
Haemodilution-induced changes in coagulation and effects of haemostatic components under flow conditions
- https://academic.oup.com/bja/article-abstract/111/6/1013/290990
- S Ogawa, T Ohnishi, K Hosokawa… - British journal of …, 2013 - academic.oup.com
- … The membrane was then incubated with a sheep anti-human thrombin (Affinity Biologicals, Ancaster, ON, Canada) or a rabbit anti-human fibrinogen antibody (AssayPro, St Charles, MO…
Coagulation, fibrinolysis and inhibitors in failing filters during continuous venovenous hemofiltration in critically Ill patients with acute kidney injury: effect of …
- https://karger.com/bpu/article/39/4/297/48520
- L Schilder, SA Nurmohamed, PM ter Wee… - Blood …, 2015 - karger.com
- Introduction: The mechanisms of early filter failure and clotting with different anticoagulation modalities during continuous venovenous hemofiltration (CVVH) are largely unknown. …
Inflammatory responses is induced in pulmonary embolic lung: evaluation by a reproducible pulmonary embolism model in mice
- https://www.biorxiv.org/content/10.1101/2022.07.29.501960.abstract
- H Okabe, H Kato, M Yoshida, M Kotake, R Tanabe… - bioRxiv, 2022 - biorxiv.org
- … kit for human (AssayPro, MO, USA). For clot formation, 100 μL of plasm was mixed with 2.5 μl of 1M CaCl 2 (nacalai tesqu, Kyoto, Japan) and 10 μl of human thrombin (nacalai tesqu), …
A multiparametric fluorescence assay for screening aptamer–protein interactions based on microbeads
- https://www.nature.com/articles/s41598-022-06817-0
- C Schmidt, A Kammel, JA Tanner, AB Kinghorn… - Scientific Reports, 2022 - nature.com
- For improving aptamer-ligand binding we have developed a screening system that defines optimal binding buffer composition. Using multiplex assays, one buffer system is needed …
The role of plasminogen activator inhibitor 1 in predicting sepsis-associated liver dysfunction: an observational study
- https://www.mdpi.com/1660-4601/20/6/4846
- E Woźnica-Niesobska, P Leśnik, J Janc… - International Journal of …, 2023 - mdpi.com
- Sepsis-associated liver dysfunction (SALD) is associated with a poor prognosis and increased mortality in the intensive care unit. Bilirubin is one of the components of Sequential Organ …
Guillermo Moñux1, Jose J. Zamorano-León2, Pablo Marqués1, Bernardo Sopeña2, JM García-García3, G. Laich de Koller4, Bibiana Calvo-Rico3, Miguel …
- no link
- CL Mancha, AX el Sabio, C de Madrid - Br J Clin Pharmacol, 2017
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Design and Preparation of Nanoparticle Dimers for SERS Detection
- https://apps.dtic.mil/sti/html/tr/ADA575625/
- GC Bazan - 2012 - apps.dtic.mil
- The overarching objectives of this proposal were to develop novel reagents for the detection and identification of various proteins, antibodies, and antigens, based on the remarkable …
The role of Plasminogen Activator Inhibitor 1 in predicting sepsis-associated liver dysfunction: an observational study
- https://www.researchsquare.com/article/rs-46756/latest
- EW Niesobska, P Lesnik, R Woznica, J Janc… - 2021 - researchsquare.com
- Background: Sepsis-associated liver dysfunction (SALD) is associated with poor prognosis and increased mortality in the Intensive Care Unit. Bilirubin is one of the components of …
Effect of two lipoprotein (a)-associated genetic variants on plasminogen levels and fibrinolysis
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments
- https://www.mdpi.com/1660-3397/17/4/195
- R Guan, Y Peng, L Zhou, W Zheng, X Liu, P Wang… - Marine Drugs, 2019 - mdpi.com
- … Human factor XII was from Assaypro (USA). All other chemicals used were of analytical … 60 nM factor IXa (30 μL) (containing human thrombin, calcium, and synthetic phospholipids) in a …
An apolipoprotein CIII-derived peptide, Hatktak, activates macromolecular activators of phagocytosis from platelets (MAPPs)
- https://www.intechopen.com/chapters/39524
- H Sakamoto, M Ueno, W Bin, Y Nagai… - Lipoproteins-Role in …, 2012 - intechopen.com
- 2. Materials and methods This study was approved by the local institutional review board of our university hospital. The procedures followed were in accordance with the Helsinki …
人工寒潮促发大鼠脑卒中发病前的凝血和纤溶系统功能的变化△
- no link
- 林健雯， 施晓耕， 廖松洁， 解龙昌， 刘春岭， 黄如训 - 血栓与止血学, 2008
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Programmable Nanomaterials for Detoxification
- https://etda.libraries.psu.edu/catalog/23701
- N Chen - 2015 - etda.libraries.psu.edu
- … The human thrombin ELISA kit was purchased from Assaypro (St. Charles, MO). … The thrombin concentration in the supernatant was measured using human thrombin ELISA kit …
The short term effects of Endovascular Aneurysm Repair (EVAR) on coagulation and cardiovascular morbidity and mortality in patients with infra-renal Abdominal …
- https://etheses.bham.ac.uk/id/eprint/3727/
- R Davies - 2012 - etheses.bham.ac.uk
- OBJECTIVE: Patients undergoing open repair of asymptomatic abdominal aortic aneurysms (AAA) demonstrate a prothrombotic state that initially deteriorates in the peri-operative …
高血压病患者腹腔镜气腹后凝血标志物的变化
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- 高峡， 计嘉军， 付建柱 - 中国医药导报, 2014
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腹腔镜与开腹胃癌切除手术前后凝血和纤溶分子标志物变化的对比研究
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- 罗利民， 胡明 - 中国农村卫生, 2013
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Autologous fibrinogen purification and concentration for use in fibrin sealant
Substituição gênica ortotópica de porco para humano baseada em CRISPR/Cas9 e recombinases para xenotransplante
Modificación de mecanismos asociados a la patogénesis y evolución de aneurismas de aorta abdominal mediante inhibición del factor Xa con rivaroxabán
血液透析患者穿刺肢体损伤的原因分析及护理
- no link
- 卢远征， 李长青 - 中国农村卫生, 2013
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