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Human Tissue-type Plasminogen Activator (tPA)(Total tPA) ELISA Kit (with Control)

Name: Human Tissue-type Plasminogen Activator (tPA)(Total tPA) ELISA Kit (with Control)
Brand: AssayMax&trade; ELISA Kits
SKU: ET2001-7
Availability: InStock

$453.00

Catalog Number: ET2001-7

This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Product Size:96 Well Plate

Catalog Number. ET2001-7 Categories: ELISA Kits, Kits, Sandwich ELISA Tag: tPA Brand: AssayMax™ ELISA Kits

Additional information

Format	Sandwich ELISA
Entrez Gene	25927
Components	Biotinylated Human tPA Antibody, Chromogen Substrate (1x), Human tPA Microplate, Human tPA Standard, MIX Diluent Concentrate (10x), Positive Control, Sealing Tapes, SP Conjugate (100x), Stop Solution (1x), Wash Buffer Concentrate (20x)
TIme	4 hours
Sensitivity	56 pg/ml
Range	0.313 – 10 ng/ml
Samples Type	Cell Culture Supernatants, Milk, Plasma, Serum
Associated Disease	Cancer
Species	Human
UniProt	P00750
Storage	Refer to component labels for details
Plex	1
Usage	For Research Use Only, Not To Be Used For Diagnostic Purposes

Documentation

Publications

"* Polaska P et al. (2023) Coagulation abnormalities as predictors of renal dysfunction in heart failure with reduced ejection fraction. Medical Studies.39 (2): 148-158.
"* Sabouni R et al. (2021) Drospirenone effects on the plasminogen activator system in immortalized human endometrial endothelial cells. Reprod Sci. 28(7):1974-1980.
"* Ravi GK et al. (2021) Effect of tranexamic acid on blood loss, coagulation profile, and quality of surgical field in intracranial meningioma resection: A prospective randomized, double-blind, placebo-controlled study. Surg Neurol Int. 12:272.
"* Nakano T et al. (2021) Arsenite Inhibits Tissue-Type Plasminogen Activator Synthesis through NRF2 Activation in Cultured Human Vascular Endothelial EA.hy926 Cells. Int J Mol Sci. 22(2):739.
"* Nagelkirk PR et al.(2021) Regular Resistance Training Enhances Fibrinolytic Potential but Does Not Affect Coagulation. Med Sci Sports Exerc. 53(11):2318-2323.
"* Maguire D et al. (2021) Post-traumatic stress disorder: A biopsychosocial case-control study investigating peripheral blood protein biomarkers. Biomarkers in Neuropshchiatry 5:100042.
"* Hara T et al. (2021) Cadmium induces plasminogen activator inhibitor-1 via Smad2/3 signaling pathway in human endothelial EA. hy926 cells. J.Toxicol.Sci. 46(5):249-253.
"* Tahtamouni LH et al. (2020) Alu-repeat polymorphism in the tissue plasminogen activator (t-PA) gene, seminal t-PA concentration, and male fertility impairment: A case-control study. Int J Reprod Biomed. 18(8):571-578.
"* Sackett JR et al. (2020) Hemostatic Adaptations to High Intensity Interval Training in Healthy Adult Men. Int J Sports Med. 41(12):867-872.
"* Schmitt FCF et al. (2019) Acute fbrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study. Ann. Intensive Care. 9:19.
"* Siennicka A et al. (2018) Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro. Biomed Res Int. 2018: 3205324.
"* Siennicka A et al. (2018) Tissue factor levels and the fibrinolytic system in thin and thick intraluminal thrombus and underlying walls of abdominal aortic aneurysms. Journal of Vascular Surgery.
"* Rhone P (2018) Comprehensive analysis of haemostatic profile depending on clinicopathological determinants in breast cancer patients. Biosci Rep. 29;38(2)
"* Imoto Y et al. (2018) Short chain fatty acids induce tissue plasminogen activator in airway epithelial cells via GPR 41&43. Clin Exp Allergy. 48(5): 544-554.
"* Sun W et al. (2017) A combined therapy of rtPA-loaded thermoresponsive gels and ultrasound on hematoma in a rat model of intracerebral hemorrhage. RSC Adv. 7:15809-15816.
"* Bystricky B et al. (2017) Relationship between circulating tumor cells and tissue plasminogen activator in patients with early breast cancer. Anticance Res. 37(4): 1787-1791.
"* Zhou Y et al. (2016) Intervention of chlorogenic acid, caffeic acid and ferulic acid on the expression of inflammation-related molecules in endothelial cells caused by complement bypass activation. Chi.Pharma. Bulletin. 32(12): 1723-1728.
"* Lee JM (2016) Hemostatic markers and long-term risk of intracerebral hemorrhage in postmenopausal women. J Stroke Cerebrovasc Dis. 25(7): 1639-1643.
"* Halim SA et al. (2015) Simultaneous Consideration of Multiple Candidate Protein Biomarkers for Long-Term Risk for Cardiovascular Events. Circ Cardiovasc Genet. 8(1):168-77
"* Topcuoglu A et al. (2014) Effects of hormone replacement therapy on plasma and tissue fibrinolytic activity in a rat model of surgically induced menopause. Clin Invest Med. 2014 Apr 1;37(2):E85-92
"* Akkok B et al. (2014) Pleural effusion and plasma levels of fibrinolytic parameters in tuberculosis pleurisy and contribution to the diagnosis. Eurasian J Pulmonol. 16: 84-88
"* Akkok B et al. (2014) Pleural effusion and plasma levels of fibrinolytic parameters in tuberculosis pleurisy and contribution to the diagnosis. Eurasian J Pulmonol. 16: 84-88
"* Vieira ML et al. (2013) Interaction of Leptospira interrogans with Human Proteolytic Systems Enhances Dissemination through Endothelial Cells and Protease Levels. Infect Immun. 81(5):1764-74. doi: 10.1128/IAI.00020-13. Epub 2013 Mar 11
"* Takabayashi T et al. (2013) Excessive fibrin deposition in nasal polyps caused by fibrinolytic impairment through reduction of tissue plasminogen activator expression. Am J Respir Crit Care Med. 187(1):49-57.
"* Siennicka A et al. (2013) Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? J Physiol Pharmacol. 64(3):321-30
"* Nsimba MM et al. (2013) Effect of a Congolese herbal medicine used in sickle cell anemia on the expression of plasminogen activators in human coronary aortic endothelial cells culture. J Ethnopharmacol. 146(2):594-9
"* Ekwere T et al. (2013) Assessment of some plasma fibrinolytic proteins in sickle cell anemia patients in steady state and in vaso-occlusive crises. Journal of Applied Hematology. 4(4):131-136
"* Baumer W et al. (2013) Pharmacokinetics and thrombolytic effects of the recombinant tissue-type plasminogen activator in horses. BMC Veterinary Research 9:158
"* Zhu H et al. (2012) Activation of coagulation, anti-coagulation, fibrinolysis and the complement system in patients with urticaria. Asian Pac J Allergy Immunol 31:43-50
"* Zhou Y et al. (2012) The high-level expression of human tissue plasminogen activator in the milk of transgenic mice with hybrid gene locus strategy. Mol Biotechnol. 50(2):137-44.
"* Vieira ML et al. (2012) The interaction of Leptospira interrogans with juman proteolytic system enhaces dissemination through endothelial cells and the levels of plasminogen activators and matrix metalloprotease-9. University of Sao Paulo.
"* Qi J et al. (2012) A novel fibrinogenase from Agkistrodon acutus venom protects against DIC via direct degradation of thrombosis and activation of protein C. Biochem Pharmacol. 84(7):905-13.
"* Maruyama K et al. (2012) Plasma levels of platelet-derived microparticles are increased after anaerobic exercise in healthy subjects. J Atheroscler Thromb. 19 (6):585-587
"* Tuttolomondo A et al. (2010) Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke. Atherosclerosis. 213(1):311-8.
"* Turfaner N et al. (2010) Ezetimibe Therapy and Its Influence on Oxidative Stress and Fibrinolytic Activity. South Med J. 103:428-433
"* Suzuki N et al. (2010) GnRH receptor and peritoneal plasmin activity. Gynecol Endocrinol. 26(9):669-672
"* Suzuki N and Imai A (2010) HMG-CoA reductase inhibitor lovastatin upregulates plasminogen activator production through RhoA-signaling in peritoneal cell line Met5A. Gynecol Surg. 7:189-193.
"* Munuswamy-Ramanujam G et al. (2010) Neuroserpin, a thrombolytic serine protease inhibitor (serpin), blocks transplant vasculopathy with associated modification of T-helper cell subsets. Thromb Haemost. 103(3):545-555
"* Kesavan K et al. (2010) Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects. J Biol Chem. 285(7):4366-4374
"* Tabak O et al. (2009) Hypertension and hemostatic/fibrinolytic balance disorders. Clin Invest Med. 32(6):E285
"* Markosyan N and Duffy DM (2009) Prostaglandin E2 acts via multiple receptors to regulate plasminogen-dependent proteolysis in the primate periovulatory follicle. Endocrinology. 150(1):435-44
"* He WJ et al. (2008) Activated protein C ratio, plasma tissue factor activity and activated factor VII in Chinese patients with coronary heart disease. Eur J Med Res. 13:47-51
"* Demirel A et al. (2008) Is Familial Mediterranean Fever a thrombotic disease or not? Eur J Pediatr. 167(3):279-285
"* Katsutani M et al. (2007) Glucose-Based PD Solution, But Not Icodextrin-Based PD Solution, Induces Plasminogen Activator Inhibitor-1 and Tissue-Type Plasminogen Activator in Human Peritoneal Mesothelial Cells via ERK1/2. Ther Apher Dial. 11(2): 94-100.
"* Nagai T et al. (2006) The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1. The Journal of Neuroscience 26(47):12374-12383
"* Sheikh AM et al. (2005) Lysophosphatidylcholine induces tPA gene expression through CRE-dependent mechanism. Biochem Biophys Res Commun. 329(1):71-77
"* Mataga N et al. (2004) Experience-Dependent Pruning of Dendritic Spines in Visual Cortex by Tissue Plasminogen Activator. Neuron 44:1031-1041

Human Tissue-type Plasminogen Activator (tPA)(Total tPA) ELISA Kit (with Control)

Additional information

Documentation

Publications

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