Publications (99 results)
Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.Poly (ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease
Curcumin ameliorates diabetic nephropathy by suppressing NLRP3 inflammasome signaling
- https://onlinelibrary.wiley.com/doi/abs/10.1155/2017/1516985
- M Lu, N Yin, W Liu, X Cui, S Chen… - BioMed research …, 2017 - Wiley Online Library
- … assay (ELISA) kits for mouse albumin were acquired from Assaypro (St. Charles, MO, USA). … Urinary albumin concentration was measured using a mouse albumin ELISA kit (Assaypro, …
Leptin-mediated reactive oxygen species production does not significantly affect primary mouse hepatocyte functions in vitro
Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress
Identification of hepatocyte-primed cholangiocytes in the homeostatic liver by in vivo lentiviral gene transfer to mice and non-human primates
Poly (ADP-ribose) polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita mice
- https://www.spandidos-publications.com/ijmm/28/4/629
- VR Drel, P Pacher, R Stavniichuk… - International …, 2011 - spandidos-publications.com
- Poly (ADP-ribose) polymerase (PARP) activation has been implicated in the pathogenesis of diabetic complications, including nephropathy and peripheral neuropathy. This study …
Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice
- https://karger.com/pha/article-abstract/88/1-2/88/271877
- LH Wang, JS Liu, WB Ning, QJ Yuan, FF Zhang… - Pharmacology, 2011 - karger.com
- Background/Aims: Fluorofenidone [1-(3-fluorophenyl)-5-methyl-2-(1H)-pyridone, AKF-PD], a novel pyridone agent, showed potent antifibrotic properties. The aim of the present study …
Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells …
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay
- https://www.embopress.org/doi/abs/10.1002/emmm.201201475
- L Fiorentino, M Cavalera, S Menini… - EMBO molecular …, 2013 - embopress.org
- … Urine albuminuria was determined using a mouse albumin ELISA kit (Assaypro, St. Charles, MO) and a mouse creatinine ELISA kit (Cusabio, Newark, DE) according to the …
MASP‐2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes
- https://onlinelibrary.wiley.com/doi/abs/10.1111/sji.13348
- H Charlotte Brinck, H Lene, D Tom… - Scandinavian …, 2024 - Wiley Online Library
- … Urinary albumin levels were quantified with a Mouse Albumin Elisa Kit (AssayPro, cat.no: EMA2201-1), and creatinine plasma levels were measured with a Creatinine Assay kit (Abcam, …
Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice
eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype
Fluorofenidone Offers Improved Renoprotection at Early Interventions during the Course of Diabetic Nephropathy in db/db Mice via Multiple Pathways
MAPEG expression in mouse embryonic stem cell-derived hepatic tissue system
- https://www.liebertpub.com/doi/abs/10.1089/scd.2007.0241
- DY Zhu, Y Du, X Huang, MY Guo, KF Ma… - Stem cells and …, 2008 - liebertpub.com
- The expressions of membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG), a superfamily involved in both inflammation and cell protection, were …
Consequences of surgical stress on the kinetics of skin wound healing: partial hepatectomy delays and functionally alters dermal repair
A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V‐ATPase a4 subunit in the proximal tubule
- https://www.embopress.org/doi/abs/10.1002/emmm.201201527
- JC Hennings, N Picard, AK Huebner… - EMBO molecular …, 2012 - embopress.org
- The V‐ATPase is a multisubunit complex that transports protons across membranes. Mutations of its B1 or a4 subunit are associated with distal renal tubular acidosis and deafness. In …
A new, easily generated mouse model of diabetic kidney fibrosis
- https://www.nature.com/articles/s41598-019-49012-4
- X He, T Zhang, M Tolosa, SK Goru, X Chen… - Scientific Reports, 2019 - nature.com
- … Prior to sacrifice, mice underwent 24 hour metabolic caging, and urinary albumin excretion was determined using an AssayMax mouse albumin ELISA kit (Assaypro, St. Charles, MO). …
Morphine promotes renal pathology in sickle mice
- https://www.tandfonline.com/doi/abs/10.2147/IJNRD.S33813
- ML Weber, D Vang, PE Velho, P Gupta… - … of Nephrology and …, 2012 - Taylor & Francis
- Patients with sickle cell disease (SCD) are often treated with opioids for severe pain. Although opioids are known to have renal-specific effects, their role in nephropathy in SCD remains …
Reduced beta 2 glycoprotein I improves diabetic nephropathy via inhibiting TGF-β1-p38 MAPK pathway
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4440048/
- T Wang, SS Chen, R Chen, DM Yu… - International journal of …, 2015 - pmc.ncbi.nlm.nih.gov
- … Urine albumin concentration was determined using the mouse albumin ELISA kit (Assaypro, USA) according to the manufacturer’s instructions. The serum levels of glucose, urea …
Inflammatory cytokine TNFα promotes the long-term expansion of primary hepatocytes in 3D culture
- https://www.cell.com/cell/fulltext/S0092-8674(18)31504-6
- WC Peng, CY Logan, M Fish, T Anbarchian… - Cell, 2018 - cell.com
- In the healthy adult liver, most hepatocytes proliferate minimally. However, upon physical or chemical injury to the liver, hepatocytes proliferate extensively in vivo under the direction of …
A double-hit pre-eclampsia model results in sex-specific growth restriction patterns
eNOS knockout mouse as a model of fetal growth
Lgr5+ stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool
Articles in PresS. Am J Physiol Regul Integr Comp Physiol (May 2, 2012). doi: 10.1152/ajpregu. 00600.2011
Analysis of the expression pattern and knock-out phenotype of Slit-like 2 (Slitl2) in the mouse
- https://core.ac.uk/download/pdf/210658459.pdf
- AM Mayer - core.ac.uk
- Mouse embryonic development takes 19 days on average. It begins with a single cell, namely the fertilized egg, or zygote. The zygote undergoes cleavage divisions to form blastomeres…
Analysis of the expression pattern and knock-out phenotype of Slit-like 2 (Slitl2) in the mouse
- https://refubium.fu-berlin.de/handle/fub188/1977
- AM Mayer - 2011 - refubium.fu-berlin.de
- The murine Slit-like 2 (Slitl2) gene was first identified in 2002, and so far, no reports have been published on it. This thesis aimed at answering two basic questions when first analyzing …
食塩/アルドステロンによる心臓の炎症と線維化促進の分子機序: ASK1 を介する酸化ストレス亢進と組織レニン・アンジオテンシン系活性化の重要性
Untersuchungen zu der Rolle der extrazellulären Matrix bei Fibrose und bei Tumoren
Localization of type 1 17beta-hydroxysteroid dehydrogenase mRNA and protein in syncytiotrophoblasts and invasive cytotrophoblasts in the human term villi
- https://joe.bioscientifica.com/view/journals/joe/165/2/217.xml
- M Bonenfant, PR Provost, R Drolet… - Journal of …, 2000 - joe.bioscientifica.com
- The 17beta-hydroxysteroid dehydrogenases (17beta-HSDs) play a key role in the synthesis of sex steroids. The hallmark of this family of enzymes is the interconversion, through their …
Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease
Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study
Nrf2 Activation Does Not Protect from Aldosterone-Induced Kidney Damage in Mice
miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia
RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state
The potent antioxidant MitoQ protects against preeclampsia during late gestation but increases the risk of preeclampsia when administered in early pregnancy
Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system
The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney. Antioxidants (Basel)
A double-hit pre-eclampsia model results in sex-specific growth restriction patterns
Reversing CXCL10 Deficiency Ameliorates Kidney Disease in Diabetic Mice
Angiotensin II type 1a receptor-deficient mice develop angiotensin II-inducedoxidative stress and DNA damage without blood pressure increase
Relevance of the angiotensin II type 1a receptor and the NADPH oxidase for the creation Angiotensin II-mediated DNA damage
Integrin avb6 Critically Regulates Hepatic Progenitor, Cell Function and Promotes Ductular Reaction, Fibrosis, and Tumorigenesis
The atrial natriuretic peptide (ANP) knockout mouse does not exhibit the phenotypic features of pre-eclampsia or demonstrate fetal growth restriction
Prostaglandin I2 Receptor Agonism Preserves beta-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms
Albumin production and cell proliferation
Effect of Prenatal Hypoxia in Transgenic Mouse Models of Preeclampsia and Fetal Growth Restriction
Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo
FcGammaRIIb on Myeloid Cells and Intrinsic Renal Cells Rather than B Cells Protects from Nephrotoxic Nephritis
Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus
Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay
Early-Outgrowth Bone Marrow Cells Attenuate Renal Injury and Dysfunction Via an Antioxidant Effect in a Mouse Model of Type 2 Diabetes
eNOS Deficiency Predisposes Podocytes to Injury in Diabetes
Morphine promotes renal pathology in sickle mice
Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress
Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells alone
Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpression
eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype
A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule
Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice
Long-Term Administration of the Histone Deacetylase Inhibitor Vorinostat Attenuates Renal Injury in Experimental Diabetes through an Endothelial Nitric Oxide Synthase-Dependent Mechanism
Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease
The molecular mechanizm of aldosterone/sale-induced cardiac inflammation and fibrosis; critial role of the enhancement of cardiac oxidative stress and the activation of cardiac renin-angiotensin system, via apoptois signal regulating kinases 1 (ASK1)
Consequences of surgical stress on the kinetics of skin wound healing: Partial hepatectomy delays and functionally alters dermal repair
MAPEG Expression in Mouse Embryonic Stem Cell-Derived Hepatic Tissue System
* Gibson J et al. (2025) Validation of Clinical-Grade Electroporation Systems for CRISPR-Cas9-Mediated Gene Therapy in Primary Hepatocytes for the Correction of Inherited Metabolic Liver Disease. Cells. 14(10):711. doi: 10.3390/cells14100711.
* Packialakshmi B et al. (2024) Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study Front Physiol. 15:1300667.
* Brinks R et al. (2023) Nrf2 Activation Does Not Protect from Aldosterone-Induced Kidney Damage in Mice. Antioxidants (Basel). 12(3):777
* Hu M et al. (2022) miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia. Mol Ther Nucleic Acids. 30:143-161.
* Belenguer G et al. (2022) RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state. Nat Commun. 13(1):334.
* Yang Y et al. (2021) The potent antioxidant MitoQ protects against preeclampsia during late gestation but increases the risk of preeclampsia when administered in early pregnancy. Antioxid Redox Signal. 34(2):118-136.
* Kostrzewski T et al. (2021) Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system. Commun Biol. 4(1):1080.
* Zimnol A et al. (2020) The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney. Antioxidants (Basel). 9(7):586.
* Stojanovska V et al. (2019) A double-hit pre-eclampsia model results in sex-specific growth restriction patterns. Dis Model Mech. 12(2):dmm035980.
* Zhang Y et al. (2018) Reversing CXCL10 Deficiency Ameliorates Kidney Disease in Diabetic Mice. Am J Pathol. 188(12):2763-2773
* Zimnol A et al. (2017) Angiotensin II type 1a receptor-deficient mice develop angiotensin II-inducedoxidative stress and DNA damage without blood pressure increase. Am J Physiol Renal Physiol. 313(6): F1264-F1273.
* Zimnol A (2016) Relevance of the angiotensin II type 1a receptor and the NADPH oxidase for the creation Angiotensin II-mediated DNA damage. Julius Maximilians University of Wurzburg. Ph.D. Thesis.
* Peng ZW et al. (2016) Integrin avb6 Critically Regulates Hepatic Progenitor, Cell Function and Promotes Ductular Reaction, Fibrosis, and Tumorigenesis. Hepatology. 63(1): 217-232.
* Finn-Sell SL et al. (2016) The atrial natriuretic peptide (ANP) knockout mouse does not exhibit the phenotypic features of pre-eclampsia or demonstrate fetal growth restriction. Placenta. 42:25-27.
* Batchu SN et al. (2016) Prostaglandin I2 Receptor Agonism Preserves beta-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms. Diabetes. 65(5):1398-1409
* Saetrom P (2014) Albumin production and cell proliferation. Patent application: EP20120730246.
* Rueda-Clausen CF et al. (2014) Effect of Prenatal Hypoxia in Transgenic Mouse Models of Preeclampsia and Fetal Growth Restriction. Reprod Sci. 21(4):492-502. Epub 2013 Sep 30.
* Reebye V et al. (2014) Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo. Hepatology. 59(1):216-27
* Sharp PE et al. (2013) FcGammaRIIb on Myeloid Cells and Intrinsic Renal Cells Rather than B Cells Protects from Nephrotoxic Nephritis. J Immunol. 190(1):340-8
* Poudel R et al. (2013) Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus. PLoS One. 8(5):e64401
* Fiorentino L et al. (2013) Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay. EMBO Mol Med. 2013 Mar;5(3):441-55. Epub 2013 Feb 12
* Zhang Y et al. (2012) Early-Outgrowth Bone Marrow Cells Attenuate Renal Injury and Dysfunction Via an Antioxidant Effect in a Mouse Model of Type 2 Diabetes. Diabetes. 61(8):2114-25
* Yuen DA et al.(2012) eNOS Deficiency Predisposes Podocytes to Injury in Diabetes. J Am Soc Nephrol. 2012 Nov;23(11):1810-23. doi: 10.1681/ASN.2011121170. Epub 2012 Sep 20
* Weber ML et al. (2012) Morphine promotes renal pathology in sickle mice. Int J Nephrol Renovasc Dis. 2012; 5: 109?118
* Shevalye H et al. (2012) Prediabetic nephropathy as an early consequence of the high-calorie/high-fat diet: relation to oxidative stress. Endocrinology. 153(3):1152-1161
* Sharp PE et al. (2012) Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells alone. Mol Immunol. 50(1-2):49-56
* Min JH et al. (2012) Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpression. Respir Res. 20;13:58
* Kusinski LC et al. (2012) eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype. Am J Physiol Regul Integr Comp Physiol303: R86-R93.
* Hennings JC et al. (2012) A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule. EMBO Mol Med. 4(10):1057-1071
* Wang LH et al. (2011) Fluorofenidone Attenuates Diabetic Nephropathy and Kidney Fibrosis in db/db Mice. Pharmacology. 88(1-2):88-99
* Advani A et al. (2011) Long-Term Administration of the Histone Deacetylase Inhibitor Vorinostat Attenuates Renal Injury in Experimental Diabetes through an Endothelial Nitric Oxide Synthase-Dependent Mechanism. Am J Pathol. 178(5):2205-14. doi: 10.1016/j.ajpath.2011.01.044
* Shevalye H et al. (2010) Poly(ADP-ribose) polymerase-1 (PARP-1) gene deficiency alleviates diabetic kidney disease. Biochim Biophys Acta. 1802(11):1020-1027
* Nakamura Taishi (2010) The molecular mechanizm of aldosterone/sale-induced cardiac kin=flammation and fibrosis; critial role of the enhancement of cardiac oxidative stress and the activation of cardiac renin-angiotensin system, via apoptois signal regulating kinases 1 (ASK1). Kumamoto University. Doctoral Thesis.
* Sorg H et al. (2009) Consequences of surgical stress on the kinetics of skin wound healing: Partial hepatectomy delays and functionally alters dermal repair. Wound Repair Regen. 17:367-377
* Zhu DY et al. (2008) MAPEG Expression in Mouse Embryonic Stem Cell-Derived Hepatic Tissue System. Stem Cells Dev. 17(4):775-783
