Mouse Leptin

A superactive leptin antagonist alters metabolism and locomotion in high-leptin mice

• https://www.researchgate.net/profile/Arieh-Gertler-2/publication/236039033_A_superactive_leptin_antagonist_alters_metabolism_and_locomotion_in_high-leptin_mice/links/57e9109308ae113df5204b24/A-superactive-leptin-antagonist-alters-metabolism-and-locomotion-in-high-leptin-mice.pdf
• N Chapnik, G Solomon, Y Genzer, R Miskin… - J …, 2013 - researchgate.net
• Transgenic alpha murine urokinase-type plasminogen activator (aMUPA) mice are resistant to obesity and their locomotor activity is altered. As these mice have high leptin levels, our …

Role of central leptin signaling in the starvation-induced alteration of B-cell development

• https://www.jneurosci.org/content/31/23/8373.short
• M Tanaka, T Suganami, M Kim-Saijo, C Toda… - Journal of …, 2011 - jneurosci.org
• … We next infused recombinant mouse leptin intracerebroventricularly to ob/ob mice for 7 d using a micro-osmotic pump to examine the effect of central leptin administration on B lineage …

Leptin levels in vitreous fluids of patients with diabetic retinopathy

• https://jrmi.pk/article/view/5
• AAS Bukhari, N Parveen, Q Khan, K Khan - Journal of Rehman Medical …, 2015 - jrmi.pk
• Introduction: Leptin, a 16 KDa protein hormone, plays a key role in regulating energy intake and energy expenditure, including the regulation of appetite and metabolism. Abnormalities …

Short-term feeding at the wrong time is sufficient to desynchronize peripheral clocks and induce obesity with hyperphagia, physical inactivity and metabolic disorders …

• https://www.sciencedirect.com/science/article/pii/S0026049516000342
• Y Yasumoto, C Hashimoto, R Nakao, H Yamazaki… - Metabolism, 2016 - Elsevier
• Background The circadian clock regulates various physiological and behavioral rhythms such as feeding and locomotor activity. Feeding at unusual times of the day (inactive phase) is …

Hepatocyte-specific fibroblast growth factor 21 overexpression ameliorates high-fat diet-induced obesity and liver steatosis in mice

• https://www.sciencedirect.com/science/article/pii/S0023683722000678
• K Yano, K Yamaguchi, Y Seko, S Okishio, H Ishiba… - Laboratory …, 2022 - Elsevier
• Fibroblast growth factor (FGF) 21 is an endocrine growth factor mainly secreted by the liver in response to a ketogenic diet and alcohol consumption. FGF21 signaling requires co-…

Identification of a Lactobacillus plantarum strain that ameliorates chronic inflammation and metabolic disorders in obese and type 2 diabetic mice

• https://www.sciencedirect.com/science/article/pii/S0022030215008851
• T Toshimitsu, J Mochizuki, S Ikegami, H Itou - Journal of dairy science, 2016 - Elsevier
• In this study, we identified a strain of lactic acid bacteria (LAB) that induces high levels of IL-10 production by immune cells, and evaluated the ability of the strain to suppress chronic …

Bacteroides uniformis CECT 7771 alleviates inflammation within the gut-adipose tissue axis involving TLR5 signaling in obese mice

• https://www.nature.com/articles/s41598-021-90888-y
• E Fabersani, K Portune, I Campillo, I López-Almela… - Scientific reports, 2021 - nature.com
• This study investigated the immune mechanisms whereby administration of Bacteroides uniformis CECT 7771 reduces metabolic dysfunction in obesity. C57BL/6 adult male mice were …

Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction

• https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202150
• SABM Aarts, ME Reiche, M Den Toom, L Beckers… - PloS one, 2018 - journals.plos.org
• … Adipokine levels in the plasma were measured using the mouse leptin ELISA Kit (ChrystalChem) and the mouse adiponectin ELISA Kit (AssayPro). Plasma levels of liver enzymes were …

Depletion of CD40 on CD11c+ cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH

• https://www.nature.com/articles/s41598-019-50976-6
• S Aarts, M Reiche, M den Toom, M Gijbels, L Beckers… - Scientific reports, 2019 - nature.com
• … Plasma leptin and adiponectin levels of the DIO mice were measured using a mouse leptin ELISA Kit (ChrystalChem) and a mouse adiponectin ELISA Kit (AssayPro). Liver enzymes …

Maternal exposure to Western diet affects adult body composition and voluntary wheel running in a genotype-specific manner in mice

• https://www.sciencedirect.com/science/article/pii/S0031938417301804
• L Hiramatsu, JC Kay, Z Thompson, JM Singleton… - Physiology & …, 2017 - Elsevier
• Some human diseases, including obesity, Type II diabetes, and numerous cancers, are thought to be influenced by environments experienced in early life, including in utero. Maternal …

Free access to a running-wheel advances the phase of behavioral and physiological circadian rhythms and peripheral molecular clocks in mice

• https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116476
• Y Yasumoto, R Nakao, K Oishi - PloS one, 2015 - journals.plos.org
• Behavioral and physiological circadian rhythms are controlled by endogenous oscillators in animals. Voluntary wheel-running in rodents is thought to be an appropriate model of …

Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice

• https://elifesciences.org/articles/61736
• G Raad, F Serra, L Martin, MA Derieppe, J Gilleron… - Elife, 2021 - elifesciences.org
• … Specific primers for mouse leptin and two mouse housekeeping genes used for normalization (β-actin and 34B4 mouse genes) were purchased from Sigma (Sigma, France). We used …

Evaluation of oral antiretroviral drugs in mice with metabolic and neurologic complications

• https://www.frontiersin.org/articles/10.3389/fphar.2018.01004/full
• FJ Tsai, MW Ho, CH Lai, CH Chou, JP Li… - Frontiers in …, 2018 - frontiersin.org
• … 1; Mouse Leptin ELISA Kit) and adiponectin (Figure 3; EMA2500-1; Mouse Adiponectin ELISA Kit) were also evaluated by ELISA according to the manufacturer’s protocol (Assaypro, MO…

Bacteroides uniformis CECT 7771 alleviates inflammation within the gut-adipose tissue axis involving TLR5 signaling in obese mice

• https://ri.conicet.gov.ar/handle/11336/161554
• ME Fabersani Marrades, K Portune, I Campillo… - 2021 - ri.conicet.gov.ar
• This study investigated the immune mechanisms whereby administration of Bacteroides uniformis CECT 7771 reduces metabolic dysfunction in obesity. C57BL/6 adult male mice were …

Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic disorders

• https://www.biorxiv.org/content/10.1101/2020.05.19.104075.abstract
• G Raad, F Serra, L Martin, MA Derieppe, J Gilleron… - bioRxiv, 2020 - biorxiv.org
• … Specific primers for mouse leptin and 2 mouse housekeeping genes used for normalization (β-actin and 34B4 mouse genes) were purchased from Sigma (Sigma, France). We used …

Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth

• https://www.sciencedirect.com/science/article/pii/S2212877819300924
• I Meln, G Wolff, T Gajek, J Koddebusch, S Lerch… - Molecular …, 2019 - Elsevier
• Objective The susceptibility to abdominal obesity and the metabolic syndrome is determined to a substantial extent during childhood and adolescence, when key adipose tissue …

Cactus pear (Opuntia ficus-indica) juice fermented with autochthonous Lactobacillus plantarum S-811

• https://pubs.rsc.org/en/content/articlehtml/2019/fo/c8fo01591k
• HE Verón, PG Cano, E Fabersani, Y Sanz, MI Isla… - Food & Function, 2019 - pubs.rsc.org
• The present study aimed at investigating the lactic fermentation of cactus pear (Opuntia ficus-indica) fruit juice with the autochthonous and potentially probiotic strain Lactobacillus …

Bezafibrate regulates the expression and enzyme activity of 11β-hydroxysteroid dehydrogenase type 1 in murine adipose tissue and 3T3-L1 adipocytes

• https://journals.physiology.org/doi/abs/10.1152/ajpendo.00340.2006
• S Nakano, Y Inada, H Masuzaki… - American Journal …, 2007 - journals.physiology.org
• A clinically employed antihyperlipidemic drug, bezafibrate, has been characterized as a PPAR(α, -γ, and -δ) pan-agonist in vitro. Recent extended trials have highlighted its antidiabetic …

Adipose extracellular matrix deposition is an indicator of obesity and metabolic disorders

• https://www.sciencedirect.com/science/article/pii/S0955286322002273
• H Chen, X Yan, A Sun, L Zhang, J Zhang… - The Journal of Nutritional …, 2023 - Elsevier
• Obesity and metabolic disorders are threats to human health. Extracellular matrix (ECM) is an important member of adipose microenvironment. ECM remodeling contributes to obesity …

Peptide YY causes apathy-like behavior via the dopamine D2 receptor in repeated water-immersed mice

• https://link.springer.com/article/10.1007/s12035-018-0931-1
• C Yamada, S Mogami, H Kanno, T Hattori - Molecular Neurobiology, 2018 - Springer
• Apathy is observed across several neurological and psychiatric conditions; however, its pathogenesis remains unclear. We clarified the involvement of brain–gut signaling in the …

EARLY METABOLIC AND HEPATIC EFFECTS OF PARTIAL LIPECTOMY IN OVARIECTOMIZED YOUNG RATS

• no link
• FA Mohamed, BMA El-Kafoury, NM Bahgat, AA Abd El… - Ain Shams Medical Journal, 2015
• no snippet

Z-505 hydrochloride, an orally active ghrelin agonist, attenuates the progression of cancer cachexia via anabolic hormones in Colon 26 tumor-bearing mice

• https://www.sciencedirect.com/science/article/pii/S0014299917303679
• M Yoshimura, Y Shiomi, Y Ohira, M Takei… - European Journal of …, 2017 - Elsevier
• Cancer cachexia is a progressive wasting syndrome characterized by anorexia and weight loss, specifically muscle wasting and fat depletion. There is no therapeutic agent for …

Possible role of central interleukins on the anorexigenic effect of lipopolysaccharide in chicks

• https://www.tandfonline.com/doi/abs/10.1080/00071668.2017.1280774
• T Tachibana, T Kodama, S Yamane… - British Poultry …, 2017 - Taylor & Francis
• The purpose of the present study was to determine if central interleukin-1β (IL1β), interleukin-6 (IL6) and interleukin-8 (IL8) affect feeding behaviour in chicks (Gallus gallus) and …

Impaired metabolic and hepatic functions following subcutaneous lipectomy in adult obese rats

• https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/EP087670
• BMA El‐Kafoury, NM Bahgat… - Experimental …, 2019 - Wiley Online Library
• … (1998) using a rat and mouse leptin ELISA kit supplied by BioVendor (Brno, Czech Republic). Similarly, plasma adiponectin was measured according to Tsao, Lodish, and Fruebis (2002…

Early-Life Effects of Diet, Exercise, and Maternal Environment on Adult Activity Levels in Mice Selectively Bred for High Voluntary Wheel-Running Behavior

• https://search.proquest.com/openview/bf55d56284fb1f87bc33fa53d28f8b5a/1?pq-origsite=gscholar&cbl=18750&diss=y
• MD Cadney - 2021 - search.proquest.com
• Unhealthy diets and a lack of exercise in children are leading to metabolic disorders in adults. This dissertation characterized effects of early-life experiences (phenotypic plasticity) on …

乳酸菌の慢性炎症抑制作用及び糖・脂質代謝改善作用に関する研究

• https://repository.dl.itc.u-tokyo.ac.jp/record/2004187/files/B18564.pdf
• 利光孝之 - (No Title), 2019 - repository.dl.itc.u-tokyo.ac.jp
• … ,Mouse total, HMW adiponectin ELISA kit(ALPCO, Salem, NH)を,leptin 濃度の測定には,assaymax mouse leptin ELISA Kit(Assaypro, St. Charles, MO)を用いた.アドレナリン及びノルアドレナ …

Central administration of chicken growth hormone-releasing hormone decreases food intake in chicks

• https://www.sciencedirect.com/science/article/pii/S0031938414005617
• T Tachibana, I Sugimoto, M Ogino, MSI Khan… - Physiology & …, 2015 - Elsevier
• Growth hormone-releasing hormone (GHRH) is well known as a stimulator of growth hormone (GH) secretion. GHRH not only stimulates GH release but also modifies feeding behavior …

Descifrando las funciones de la microbiota intestinal en la obesidad.

• https://riunet.upv.es/bitstream/handle/10251/174897/Resumen_Inmaculada%20L%C3%B3pez%20Almela.pdf?sequence=3
• I López Almela - 2023 - riunet.upv.es
• [ES] La obesidad es uno de los principales problemas de salud pública debido a su elevada prevalencia ya las comorbilidades asociadas, lo que se traduce en una reducción …

Descifrando las funciones de la microbiota intestinal en la obesidad

• https://riunet.upv.es/server/api/core/bitstreams/ab947e30-631d-43cc-bdcb-07a2c14ad1c7/content
• IL Almela - 2021 - riunet.upv.es
• En la actualidad, la obesidad es uno de los principales problemas de salud pública debido a su elevada prevalencia ya las comorbilidades asociadas, lo que se traduce en una …