Publications (65 results)
Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.Recombinant human GLP-1 (rhGLP-1) alleviating renal tubulointestitial injury in diabetic STZ-induced rats
Protein kinase C and protein kinase A are involved in the protection of recombinant human glucagon‐like peptide‐1 on glomeruli and tubules in diabetic rats
- https://onlinelibrary.wiley.com/doi/abs/10.1111/jdi.12956
- W Yin, Y Jiang, S Xu, Z Wang, L Peng… - Journal of diabetes …, 2019 - Wiley Online Library
- Aims/Introduction Blockade or reversal the progression of diabetic nephropathy is a clinical challenge. The aim of the present study was to examine whether recombinant human …
Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury
- https://www.nature.com/articles/nbt.1624
- Y Yu, H Jin, D Holder, JS Ozer, S Villarreal… - Nature …, 2010 - nature.com
- … The AssayMax rat albumin ELISA kit from AssayPro, which is a competitive ELISA assay, was used to detect urinary albumin. Sample urines were diluted 1:20 for this assay (2.5 μl urine/…
C-peptide ameliorates renal injury in type 2 diabetic rats through protein kinase A-mediated inhibition of fibronectin synthesis
Simvastatin ameliorates diabetic nephropathy by attenuating oxidative stress and apoptosis in a rat model of streptozotocin-induced type 1 diabetes
Flow enhances phenotypic and maturation of adult rat liver organoids
Insulin increases glomerular filtration barrier permeability through dimerization of protein kinase G type Iα subunits
Alpha-mangostin attenuates diabetic nephropathy in association with suppression of acid sphingomyelianse and endoplasmic reticulum stress
Renoprotective effects of fenofibrate via modulation of LKB1/AMPK mRNA expression and endothelial dysfunction in a rat model of diabetic nephropathy
- https://karger.com/pha/article/95/5-6/229/272392
- NM Al-Rasheed, NM Al-Rasheed, HA Attia… - Pharmacology, 2015 - karger.com
- … The urinary albumin excretion was estimated using a Rat Albumin ELISA kit supplied by AssayPro (St. Charles, Mo., USA). Serum urea was determined using a commercial kit (…
ADAM10 as a major activator of reactive oxygen species production and klotho shedding in podocytes under diabetic conditions
Differential activations of PKC/PKA related to microvasculopathy in diabetic GK rats
- https://journals.physiology.org/doi/abs/10.1152/ajpendo.00184.2011
- H Wang, YW Jiang, WJ Zhang, SQ Xu… - American Journal …, 2012 - journals.physiology.org
- … The excretion level of urinary albumin was detected by the AssayMax Rat Albumin ELISA Kit (Assaypro) and urinary protein measured with a BCA Protein Assay Kit (Beyotime, China) …
Increased transient receptor potential canonical type 1 improves diabetic nephropathy via inhibiting NF-kappa B pathway
- no link
- ZM Yu, XY Li, JP Li, SP Dang, B Wang, Y Wu, YX Chen… - Biomed. Res. India, 2016
- no snippet
Efficient formation of three dimensional spheroids of primary hepatocytes using micropatterned multi-well plates
- https://link.springer.com/article/10.1007/s13233-019-7103-7
- DH Ha, PM Thi, P Chaudhary, JH Jeong - Macromolecular Research, 2019 - Springer
- Primary hepatocytes constitute 60-80% of liver where they play a vital role in metabolism, synthesis and storage such as vitamins, carbohydrates, proteins. When hepatocytes are grown …
Uninephrectomized high‐fat‐Fed Nicotinamide‐Streptozotocin‐Induced Diabetic Rats: A model for the investigation of diabetic nephropathy in Type 2 diabetes
- https://onlinelibrary.wiley.com/doi/abs/10.1155/2016/8317850
- VK Bayrasheva, AY Babenko… - Journal of diabetes …, 2016 - Wiley Online Library
- … Albuminuria was assayed by using rat albumin ELISA kit, purchased from Assaypro (USA), on ELx800 absorbance microplate reader (USA), and then total (24-hour) urinary excretion of …
Metformin reduces TRPC6 expression through AMPK activation and modulates cytoskeleton dynamics in podocytes under diabetic conditions
Gliquidone decreases urinary protein by promoting tubular reabsorption in diabetic Goto-Kakizaki rats
Lectin-like oxidized low-density lipoprotein 1 receptor in a reduced uteroplacental perfusion pressure rat model of preeclampsia
Dietary sodium restriction prevents kidney damage in high fructose-fed rats
“Rogue” neutrophil-subset [DEspR+ CD11b+/CD66b+] immunotype is an actionable therapeutic target for neutrophilic inflammation-mediated tissue injury–studies in …
Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways
The effect of hypoxia-induced intrauterine growth restriction on renal artery function
The exaggerated salt-sensitive response in hypertensive transgenic rats (TGR mRen-2) fostered by a normotensive female
- https://www.nature.com/articles/s41440-018-0157-7
- P Svitok, Z Husková, L Červenková, S Kikerlová… - Hypertension …, 2019 - nature.com
- Suboptimal conditions during prenatal and early postnatal development can increase risk of hypertension later in life. We studied consequences of a changed perinatal environment by …
Hyperglycemia and renal mass ablation synergistically augment albuminuria in the diabetic subtotally nephrectomized rat: implications for modeling diabetic …
- https://karger.com/nne/article/2/1/115/232406
- LH Chen, B Stead, SL Advani, N Yaqoob, K Thai… - Nephron Extra, 2012 - karger.com
- Background/Aims: While experimental models that emulate diabetic nephropathy are valuable tools for elucidating pathogenetic mechanisms and developing novel therapies, existing …
Allogeneic liver transplantation and subsequent syngeneic hepatocyte transplantation in a rat model: proof of concept for in vivo tissue engineering
- https://karger.com/cto/article/201/6/399/92121
- S Rohn, J Schroeder, H Riedel, D Polenz… - Cells Tissues …, 2016 - karger.com
- … Rat albumin concentrations were determined in cell culture supernatants using an enzyme-linked immunosorbent assay kit (rat albumin ELISA kit for cell culture samples, AssayPro, St. …
Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil–lymphocyte ratio in rats with or without hidden …
- https://www.tandfonline.com/doi/abs/10.2147/DMSO.S160301
- G Yang, R Yan, H Tong, J Zhang, B Chen… - … syndrome and obesity …, 2018 - Taylor & Francis
- Background The neutrophil–lymphocyte ratio (NLR) has been considered as an inflammatory marker in various disorders, but it is not clear whether the NLR is also elevated with …
CXCR4 promotes renal tubular cell survival in male diabetic rats: implications for ligand inactivation in the human kidney
Stress oxydant et effets bénéfiques rénaux de la restriction sodée dans l'insulinorésistance chez le rat
- https://www.sciencedirect.com/science/article/pii/S0003392812000558
- C Oudot, AD Lajoix, B Jover, C Rugale - Annales de Cardiologie et d' …, 2012 - Elsevier
- L’objectif de ce travail était d’évaluer l’influence de la restriction de l’apport alimentaire en sodium sur les changements métaboliques et rénaux associés à une insulinorésistance. À …
Prediction of sustained fetal toxicity induced by ketoprofen based on PK/PD analysis using human placental perfusion and rat toxicity data
Research Article Uninephrectomized High-Fat-Fed Nicotinamide-Streptozotocin-Induced Diabetic Rats: A Model for the Investigation of Diabetic Nephropathy in …
- https://www.academia.edu/download/98710243/8317850.pdf
- VK Bayrasheva, AY Babenko, VA Dobronravov… - 2016 - academia.edu
- … Albuminuria was assayed by using rat albumin ELISA kit, purchased from Assaypro (USA), on ELx800 absorbance microplate reader (USA), and then total (24-hour) urinary excretion of …
Rola układu purynergicznego w patogenezie zaburzeń hemodynamiki nerek w doświadczalnie indukowanej cukrzycy
Review of qualification data for biomarkers of nephrotoxicity submitted by the predictive safety testing consortium
- https://www.academia.edu/download/116918691/UCM382536.pdf
- M Blank, A De Felice, F Goodsaid, P Harlow… - Center for Drug …, 2009 - academia.edu
- … The AssayMax rat albumin ELISA kit from AssayPro (a competitive ELISA) was used for detection of urinary albumin. The summary states that urine from Carbapenem A treated male …
Úloha renální dysfunkce v patofyziologii progrese chronického srdečního selhání: preklinické studie na zvířecích modelech
* Tomoda F et al. (2025) Impact of mild renal impairment on the relationship between blood pressure and renal fractional excretion of albumin in primary hypertension. Am J Hypertens. 38(7):467-475.
* Tykvartova T et al. (2024) The impact of phosphodiesterase-5 inhibition or angiotensin-converting enzyme inhibition on right and left ventricular remodeling in heart failure due to chronic volume overload. Pharmacol Res Perspect. 12(1):e1172.
* Piwkowska A et al. (2024) ADAM10 as a major activator of reactive oxygen species production and klotho shedding in podocytes under diabetic conditions. Biochem Pharmacol. 225:116328.
* Doul J et al. (2024) Effects of renal denervation on the course of cardiorenal syndrome: insight from studies with fawn-hooded hypertensive rats. Physiol Res. 73(S3):S737-S754.
* Dabkowski K et al. (2024) Human In Vitro Oxidized Low-Density Lipoprotein (oxLDL) Increases Urinary Albumin Excretion in Rats. Int J Mol Sci. 25(10):5498.
* Rathbone T et al. (2022) Electroporation-Mediated Delivery of Cas9 Ribonucleoproteins Results in High Levels of Gene Editing in Primary Hepatocytes.
* Yeh JH et al. (2021) Effects of Dietary Fatty Acid Composition on Lipid Metabolism and Body Fat Accumulation in Ovariectomized Rats.Nutrients. 13(6):2022.
* Dabkowshi K et al. (2021) Redox regulation of hemodynamics response to diadenosine tetraphosphate an agonist of P2 receptors and renal function in diet-induced hypercholesterolemic rats. Physiol Rep. 9(11):e14888.
* Jichova S. (2020) The Role of Arachidonic Acid Metabolites in Regulation of Blood Pressure in Experimental Models of Angiotensin II-Dependent Hypertension. Charles University.
* Svitok P et al. (2019) The exaggerated salt-sensitive response in hypertensive transgenic rats (TGR mRen-2) fostered by a normotensive female. Hypertension Research. 42(4):459-468
* Saetrom P. (2019) C/ebp alpha short activating rna compositions and methods of use. US Patent application Publication. US20190249176A1
* Ha DH et al. (2019) Efficient Formation of Three Dimensional Spheroids of Primary Hepatocytes Using Micropatterned Multi-Well Plates. Macromolecular Research. pISSN 1598-5032 eISSN 2092-7673
* Melenovsky V et al. (2018) Kidney Response to Heart Failure: Proteomic Analysis of Cardiorenal Syndrome. Kidney Blood Press Res 43:1437-1450.
* Liu T et al. (2018) Alpha-mangostin attenuates diabetic nephropathy in association with suppression of acid sphingomyelianse and endoplasmic reticulum stress. Biochem Biophys Res Commun. 496(2):394-400
* Al-Rasheed NM et al. (2018) Simvastatin ameliorates diabetic nephropathy by attenuating oxidative stress and apoptosis in a rat model of streptozotocin-induced type 1 diabetes. Biomed Pharmacother. 105:290-298.
* Tanaka S et al. (2017) Prediction of sustained fetal toxicity induced by ketoprofen based on PK/PD analysis using human placental perfusion and rat toxicity data. Br J Clin Pharmacol. 83(11):2503-251
* Kasztan M et al. (2016) Extracellular purines? action on glomerular albumin permeability in isolated rat glomeruli: insights into the pathogenesis of albuminuria. Am J Physiol Renal Physiol. 311(1):F103-11. Epub 2016 Apr 13.
* AL-Onazi AS et al. (2016) Ruboxistaurin attenuates diabetic nephropathy via modulation of TGFbeta1/Smad and GRAP pathways. J Pharm Pharmacol. 68(2):219-32
* Siddiqi F et al. (2015) CXCR4 Promotes Renal Tubular Cell Survival in Male Diabetic Rats: Implications for Ligand Inactivation in the Human Kidney. Endocrinology. 156(3):1121-1132. (Rat Albumin).
* Piwkowska A et al. (2013) Insulin increases glomerular filtration barrier permeability through dimerization of protein kinase G type Ialpha subunits. Biochim Biophys Acta. 1832(6):791-804
* Oudot C et al. (2013) Dietary sodium restriction prevents kidney damage in high fructose-fed rats. Kidney Int. 83(4):674-83
* Ojima A et al. (2015) Empagliflozin, an Inhibitor of Sodium-Glucose Cotransporter 2 Exerts Anti-Inflammatory and Antifibrotic Effects on Experimental Diabetic Nephropathy Partly by Suppressing AGEs-Receptor Axis. Horm Metab Res. 47(9):686-92.
* Wang L et al. (2012) Mechanisms of the proteinuria induced by Rho GTPases. Kidney International 81(11):1075-85
* Wang H et al. (2012) Differential activations of PKC/PKA related to microvasculopathy in diabetic GK rats. Am J Physiol Endocrinol Metab. 302(2):E173-82
* Verschuren MT et al. (2012) The effect of hypoxia-induced intrauterine growth restriction on renal artery function. J Dev Orig Health Dis. 3(5):333-41.
* Oudot C et al. (2012) Oxydative stress and beneficial effect of sodium restriction on kidney damage associated with insulin. Ann Cardiol Angeiol. http://dx.doi.org/10.1016/j.ancard.2012.04.017
* Morton JS et al. (2012) Lectin-Like Oxidized Low-Density Lipoprotein 1 Receptor in a Reduced Uteroplacental Perfusion Pressure Rat Model of Preeclampsia. Hypertension. 59(5):1014-20.
* Chen LH et al. (2012) Hyperglycemia and Renal Mass Ablation Synergistically Augment Albuminuria in the Diabetic Subtotally Nephrectomized Rat: Implications for Modeling Diabetic Nephropathy. Nephron Extra. 2(1): 115-124
* Chien WS et al. (2011) Suppression of Autophagy in Rat Liver at Late Stage of Polymicrobial Sepsis. Shock 35(5):506-511
* Bolleyn J et al. (2011) Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes. Toxicol In Vitro. 25(6):1173-82
* Yu Y et al. (2010) Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury. Nature Biotechnology 28(5):470-477
* Blank M et al.(2009) Review of Qualification Data for Biomarkers of Nephrotoxicity Submitted by the Predictive Safety Testing Consortium. Center for Drug Evaluation and Research U.S. Food and Drug Administration.
