Publications (74 results)
Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.Renoprotective effect of maresin-1 in deoxycorticosterone acetate-salt-induced hypertension in rats: Targeting TLR4/NF-kB pathway
- https://journals.ekb.eg/article_401304.html
- SA Khodir, AM Gaafar, MS Amer, A Wahb… - Bulletin of Egyptian …, 2025 - journals.ekb.eg
- Background: Essential hypertension causes the kidney illness known as hypertensive nephropathy, which frequently results in both structural and functional renal impairment. A lipid …
Phosphodiesterase 5 inhibitor suppresses prostate weight increase in type 2 diabetic rats
Activation of angiotensin-converting enzyme 2 mitigates Doxorubicin induced nephrotoxicity by TLR4/NF-kB downregulation
- https://mjfmct.journals.ekb.eg/article_414128.html
- SA Khodir, SE Abdelrahman… - … Journal of Forensic …, 2025 - mjfmct.journals.ekb.eg
- The application of the anticancer antibiotic doxorubicin (Dox) has been limited due to the emergence of toxicities affecting vital organs, including the kidneys. The anti-trypanosomal …
PDE5 inhibitor potentially improves polyuria and bladder storage and voiding dysfunctions in type 2 diabetic rats
Phosphodiesterase 5 inhibitor suppresses prostate weight increase in type 2 diabetic rats
Amelioration of aflatoxin acute hepatitis rat model by bone marrow mesenchymal stem cells and their hepatogenic differentiation
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9210847/
- FAM Abo-Aziza, AKA Zaki, RM Adel… - Veterinary …, 2022 - pmc.ncbi.nlm.nih.gov
- Background and Aim: Bone marrow-derived mesenchymal stem cells (BM-MSCs) transplantation and their hepatogenic differentiated cells (HDCs) can be applied for liver injury repair …
Sitagliptin attenuates the cognitive deficits in L‐methionine‐induced vascular dementia in rats
- https://onlinelibrary.wiley.com/doi/abs/10.1155/2022/7222590
- SA Khodir, MA Faried, HI Abd-Elhafiz… - BioMed Research …, 2022 - Wiley Online Library
- Vascular dementia (VaD) is the second most prevalent type of dementia characterized by progressive cognitive deficits and is a major risk factor for the development of Alzheimer’s …
Albiflorin mitigates Renal Impairment in Hyperuricemic Rats by modulating HMGB1/TLR4/NF-kB signaling pathway
- https://journals.ekb.eg/article_418799.html
- SA Khodir, N Bayomy, KA Diab… - Bulletin of Egyptian …, 2025 - journals.ekb.eg
- Background: It is becoming more well accepted that hyperuricemia may be a contributing factor to hypertension, renal illness, and a number of detrimental effects of vascular disease. It …
Metrnl impact in streptozotocin induced diabetic nephropathy in rats, targeting Nrf2/HO-1 pathway
- https://journals.ekb.eg/article_418802.html
- SA Khodir, A Wahb, MA Ibrahim… - Bulletin of Egyptian …, 2025 - journals.ekb.eg
- Introduction: The most prevalent complications in diabetes mellitus is diabetic nephropathy (DN). Metrnl's role in endocrine metabolism has been well investigated. It has been …
Auricularia polytricha aqueous extract supplementation decreases hepatic lipid accumulation and improves antioxidative status in animal model of nonalcoholic fatty …
- https://link.springer.com/article/10.7603/s40681-014-0012-3
- WC Chiu, HH Yang, SC Chiang, YX Chou, HT Yang - BioMedicine, 2014 - Springer
- Background: Amelioration effect of Auricularia polytricha water extract (AP) on hepatic injury in an animal model of NAFLD was investigated. Methods: Forty six-week-old Wistar rats …
Astaxanthin Mitigates Streptozotocin Induced Diabetic Nephropathy, Targeting HMGB1, TLR4 and NF-κB
- https://www.ajol.info/index.php/ejhm/article/view/294016
- SA Khodir, AM Shukry, NM Abd El-aziz… - Egyptian Journal of …, 2024 - ajol.info
- … On the other hand, rat ELISA kits (TNF-α: ERT2010-1, Assaypro LLC, Saint Charles, Missouri, USA, cystatin C: ab201281, IL-6: ab100772, Abcam, Cambridge, UK) were used to …
Melatonin alleviates cisplatin induced liver toxicity in rats by up-regulation of Nrf2/HO-1 signaling pathway
Effect of probiotic fermented soy milk and gamma radiation on nitrosourea-induced mammary carcinogenesis
- https://www.academia.edu/download/35781942/1.pdf
- AR Omayma, SM El-Sonbaty, SA Aziza, AE Aboelftouh - Nature Sci, 2013 - academia.edu
- Background and aim of the work: Antioxidants can reduce damage produced by low doses of radiation on living cells. This study was designed to investigate the effects of fermented soy …
Evaluation of selenium nanoparticles as a potential chemopreventive agent against lung carcinoma
- no link
- EN Ali, SM El-Sonbaty, FM Salem - Int J Pharm Biol Sci, 2013
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A study on the immunological changes in adult male obese rats and the possible immune modulator effect of conjugated linoleic acid supplementation
- https://journals.ekb.eg/article_62793.html
- GA ASMAA, AB MOHAMED, SE ABDOU… - The Medical Journal of …, 2018 - journals.ekb.eg
- AbstractBackground: Conjugated Linoleic Acid [CLA] is suggested as a novel drug to improve obesity.Objectives: The aim of this study was to elucidate the possible role of CLA in …
METRNL mitigates oxidative stress and inflammatory drawbacks in ovalbumin/lipopolysaccharide-induced allergic airway diseases via the IKK/IκB/NF-κB signaling …
- https://link.springer.com/article/10.1007/s00210-025-04070-6
- SA Khodir, AM Shaban, E Sweed, NMA El-aziz… - Naunyn-Schmiedeberg's …, 2025 - Springer
- This study aimed to examine the potential impacts of METRNL as an antioxidant and anti-inflammatory through IκB kinase/inhibitor of nuclear factor-kappa B/nuclear factor-kappa-light-…
Effect of Probiotic Fermented Soy Milk and Gamma Radiation on Nitrosourea-Induced Mammary Carcinogenesis
Empagliflozin attenuates cyclophosphamide-induced hepatotoxicity via targeting Nrf2/HO-1 signaling, oxidative stress, and inflammation
- https://www.wjpsonline.com/index.php/wjps/article/view/293
- MG Helal - World Journal of Pharmaceutical Sciences, 2019 - wjpsonline.com
- Cyclophosphamide (CYP) is the most commonly used antineoplastic against numerous malignant tumors. Hepatic injury induced by CYP is a pivotal issue in clinical practice that limits …
Effect of lysophosphatidic acid on the immune inflammatory response and the connexin 43 protein in myocardial infarction
- https://www.spandidos-publications.com/etm/11/5/1617
- D Zhang, Y Zhang, C Zhao… - Experimental and …, 2016 - spandidos-publications.com
- Lysophosphatidic acid (LPA) is an intermediate product of membrane phospholipid metabolism. Recently, LPA has gained attention for its involvement in the pathological processes of …
MEZENKİMAL KÖK HÜCRELERİN RATLARDA CROHN HASTALIĞI MODELİNDE DOKU HASARI, İNFLAMATUAR VE ANTİNFLAMATUAR SİTOKİNLERE ETKİSİ
- https://dergipark.org.tr/en/pub/iuitfd/issue/9310/116410
- İ Şenkal, Ü Akyüz, F Yalnız, F Çiftçi… - Journal of Istanbul …, 2011 - dergipark.org.tr
- Amaç: Mezenkimal kök hücreler (MKH) T hücre oluşumunu ve antijen sunan hücreleri inhibe ederek inflamatuar sitokinlerin salınımını baskılayarak (IFN-γ, TNF-α) ve antiinflamatuar …
Acacia Saligna alleviates Stress Induced Gastric Ulcer in Rats by TLR4/NF-κB Downregulation.
- https://journals.ekb.eg/article_411717.html
- AM Negm, SA Khodir, MS Amer… - Egyptian Journal of …, 2025 - journals.ekb.eg
- Background: One of the most prevalent types of peptic ulcers is stress-induced stomach ulceration. Various research have reported the biological and pharmacological potentialities of …
Retinol exerts therapeutic effect on myocardial infarction through regulation of immune inflammatory cells and Cx43 expression
- https://www.ajol.info/index.php/tjpr/article/view/220472
- H Sun, J Zhong, X Yang, Z Guo, J Liu, B Xie… - Tropical Journal of …, 2021 - ajol.info
- Purpose: To investigate the effect of retinol on cardiac fibroblast proliferation in vitro and on fibrosis formation in mice in vivo. Methods: Proliferative potential of fibroblasts was …
MEZENKĠMAL KÖK HÜCRELERĠN RATLARDA CROHN HASTALIĞI MODELĠNDE DOKU HASARI, ĠNFLAMATUAR VE ANTĠNFLAMATUAR …
A Study on the Immunological Changes in Adult Male Obese Rats and the Possible Immune Modulator Effect of Conjugated Linoleic Acid …
- no link
- MA BENDARY, AG ABDOU, GS AMER
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Research Article Sitagliptin Attenuates the Cognitive Deficits in L-Methionine-Induced Vascular Dementia in Rats
- https://www.academia.edu/download/83604986/7222590.pdf
- SA Khodir, MA Faried, HI Abd-Elhafiz, EM Sweed - 2022 - academia.edu
- Vascular dementia (VaD) is the second most prevalent type of dementia characterized by progressive cognitive deficits and is a major risk factor for the development of Alzheimer’s …
EFFECT OF PROBIOTIC FERMENTED SOY MILK AND GAMMA RADIATION IN AMELIORATING OXIDATIVE STRESS AND APOPTOSIS ON NITROSOUREA …
Synergistic effect of aluminum and ionizing radiation upon ultrastructure, oxidative stress and apoptotic alterations in Paneth cells of rat intestine
- https://link.springer.com/article/10.1007/s11356-017-8392-z
- NA Eltahawy, SM Elsonbaty, S Abunour… - … Science and Pollution …, 2017 - Springer
- … Rat TNF-alpha ELISA kit of murine monoclonal antibody” (Assaypro, USA). Data was analyzed using 990win6 software for DV990BV4 micro plate reader, GIO DE VITA (Rome, Italy). …
Anticancer potential of nutraceutical formulation through antioxidant, anti-inflammatory, and antiproliferative mechanisms in N-methyl-N-nitrosourea-induced …
- http://greenpharmacy.info/index.php/ijgp/article/view/1288
- G Pitchaiah - International Journal of Green Pharmacy (IJGP), 2017 - greenpharmacy.info
- … [11] TNF-α concentration in rat mammary gland was measured using the “Assay Max Rat TNFalpha ELISA kit of murine monoclonal antibody” (Assaypro, 41 Triad South Drive St. …
Astaxanthin ameliorates doxorubicin-induced cognitive impairment (chemobrain) in experimental rat model: impact on oxidative, inflammatory, and apoptotic …
- https://link.springer.com/article/10.1007/s12035-017-0797-7
- SE El-Agamy, AK Abdel-Aziz, S Wahdan, A Esmat… - Molecular …, 2018 - Springer
- Chemobrain refers to a common sequelae experienced by 15–80% of cancer patients exposed to chemotherapeutics. The antineoplastic agent doxorubicin (DOX) has been implicated …
Effectiveness of Punica granatum juice in ameliorating oxidative damage and ultrastructural changes in Paneth cells of rat intestine
Phosphodiesterase-5 inhibition inhibits epithelial ATP release and restores detrusor contractility in rats with type 2 diabetes via an increase in bladder blood flow
Effect of L-carnitine supplementation on lead acetate-induced liver cell apoptosis and inflammation: Role of caspase-3 and glycogen synthase kinase-3β enzymes
The potential neuroprotective effect of diosmin in rotenone-induced model of Parkinson's disease in rats
Mechanistic perspective of protective effects of resveratrol against cisplatin-induced ovarian injury in rats: emphasis on anti-inflammatory and anti-apoptotic effects
- https://link.springer.com/article/10.1007/s00210-019-01662-x
- RS Said, EM Mantawy, E El-Demerdash - … -Schmiedeberg's archives of …, 2019 - Springer
- Chemotherapeutic platinum-containing drugs are widely used to treat a variety of cancer types; however, they cause ovarian failure and infertility. The aim of this study is to investigate …
Luteolin mitigates deoxycorticosterone acetate-salt-induced hypertension in rats by activation of Nrf2/HO-1 pathway
- https://journals.ekb.eg/article_434918.html
- SEM Elmorshdy, SA Khodir, NM Abd El-aziz… - Medicine …, 2025 - journals.ekb.eg
- Background: One of the risk factors for vascular disorders is hypertension. Several characteristics of human hypertension are replicated in the deoxycorticosterone acetate (DOCA) salt …
Determination of Aflatoxin in the Blood of Patients with Hepatopathy and Evaluation its Effect on some Immune Parameters
- http://bcsdjournals.com/index.php/jsrmbs/article/view/795
- MS Farhan, HR Alwan - Journal of Scientific Research in Medical …, 2024 - bcsdjournals.com
- … ERI3010-1, Assaypro, USA), and tumor necrosis factor-α (TNF-α) (catalog no. ERT2010-1, Assaypro, USA) were used to count cytokines amount in the serum that was collected. The …
N-butanol fraction of Olax subscorpioidea Oliv.(Olacaceae) attenuates lipopolysaccharide-induced depressive-like symptoms in mice.
- https://www.academia.edu/download/106540769/latest.pdf
- OA Adeoluwa, I Agboola, E Akinluyi, A Eduviere… - 2023 - academia.edu
- Background: The leaves of Olax subscorpioidea have become a mainstay in the management of in ammatory diseases and mental illness in folkloric medicine in Nigeria. Previous …
Protective potential of ginseng and/or coenzyme Q10 on doxorubicin-induced testicular and hepatic toxicity in rats
- https://oamjms.eu/index.php/mjms/article/view/7063
- S Khodir, A Alafify, E Omar, M Al-Gholam - Open Access Macedonian …, 2021 - oamjms.eu
- Introduction: Although doxorubicin (DOX) is a successful cancer chemotherapeutic, side effects limit the clinical utility of DOX-based therapy, including male infertility and hepatotoxicity. …
Hesperidin mitigates Doxorubicin-induced hepatic toxicity in rats, targeting JAK-STAT signaling pathway
- https://journals.ekb.eg/article_391048.html
- SA Khodir, A Nagy, N Abd El-aziz… - Mansoura Journal of …, 2025 - journals.ekb.eg
- Even though doxorubicin (DOX) is an excellent cancer chemotherapy, its adverse impacts, including hepatotoxicity, restrict its clinical usefulness. The study's goal was to assess …
Nrf2/HO-1 Pathway Mediates the Protective Impact of Metrnl on Oxaliplatin-Induced Peripheral Neuropathy in Rats
- https://journals.ekb.eg/article_383948.html
- SA Khodir, H El-Haroun, AM Gaafar… - Bulletin of Egyptian …, 2025 - journals.ekb.eg
- Introduction: While oxaliplatin (OXL) is an effective cancer chemotherapy, OXL-based therapy's practical usefulness is limited by its adverse effects, which include peripheral neuropathy …
Therapeutic Versus Preventative Use of Ginkgo biloba Extract (EGb 761) against Indomethacin-Induced Gastric Ulcer in Mice
- https://www.mdpi.com/1420-3049/27/17/5598
- AM Abd-Eldayem, SM Alnasser, HH Abd-Elhafeez… - Molecules, 2022 - mdpi.com
- The main bioactive constituents in the standardized Ginkgo biloba leaf extract (EGb 761) are the terpene lactones and flavonoid glycosides. EGb 761’s antioxidant and anti-…
Bull. of Egyp. Soc. Physiol. Sci.
Sitagliptin mitigates scopolamine-induced neurocognitive deficits via activation of Nrf2/HO-1 pathway and improved mitochondrial activity
- https://journals.ekb.eg/article_418317.html
- A Gaafar, B Mostafa, N Abd El-aziz… - The Egyptian Journal …, 2025 - journals.ekb.eg
- Background: Rats' memory is hampered by the muscarinic receptor antagonist scopolamine (Scop), which inhibits cholinergic neurotransmission. Objectives: to assess the protective …
MEZENKİMAL STROMAL HÜCRELERİN CROHN HASTALIĞI MODELİNDE İNFLAMATUAR VE PROİNFLAMATUAR SİTOKİNLERE ETKİSİ VE TEDAVİDE …
- https://nek.istanbul.edu.tr/ekos/TEZ/46916.pdf
- İV ŞENKAL - nek.istanbul.edu.tr
- In-vitro ve ın-vivo olarak kemik, yağ dokusu ve kıkırdak gibi dokulara differensiye olabilmesinin yanında hasarlı dokuya yerleşip teröpetik potansiyel göstermesi, tedaviye rezistan akut …
Protective Potential of Ginseng and/or Coenzyme Q10 on Doxorubicin-induced Testicular and Hepatic Toxicity in Rats. Open-Access Maced J Med Sci. 2021 …
- https://www.academia.edu/download/105623604/6373.pdf
- S Khodir, A Alafify, E Omar, M Al-Gholam - 2021 - academia.edu
- BACKGROUND: Although doxorubicin (DOX) is a successful cancer chemotherapeutic, side effects limit the clinical utility of DOX-based therapy, including male infertility and …
Cardioprotective effect of resveratrol analogue isorhapontigenin versus omega-3 fatty acids in isoproterenol-induced myocardial infarction in rats
- https://link.springer.com/article/10.1007/s13105-016-0494-4
- AM Abbas - Journal of physiology and biochemistry, 2016 - Springer
- Myocardial infarction (MI) is a common cause of mortality worldwide. Isorhapontigenin is a derivative of stilbene with chemical structure similar to resveratrol. The omega-3 fatty acids (FA…
Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism
- https://cdnsciencepub.com/doi/abs/10.1139/cjpp-2015-0247
- AM Abbas, HF Sakr - Canadian Journal of Physiology and …, 2016 - cdnsciencepub.com
- Inflammation is a major risk factor for cardiovascular complications. Magnesium sulfate (MgSO 4 ) has anti-inflammatory actions. Therefore we investigated the effects of levothyroxine …
Astaxanthin attenuates cardiovascular dysfunction associated with deoxycorticosterone acetate-salt-induced hypertension in rats
Rutin Exerts Antidepressant Effect in a Rat Model of Diabetes
Dapagliflozin Protection against Myocardial Ischemia by Modulating Sodium-glucose Transporter 2 Inhibitor, Silent Information Regulator 1, and Fatty Acid Synthase …
- https://oamjms.eu/index.php/mjms/article/view/10861
- E Sweed, D Sweed, N Galal… - Open Access Macedonian …, 2022 - oamjms.eu
- BACKGROUND: The emerging role of sodium-glucose transporter 2 (SGLT2) inhibitors drugs as potential therapeutic agents in myocardial ischemic (MI) injury treatment has raised the …
* Khodir SA et al. (2022) Sitagliptin Attenuates the Cognitive Deficits in L-MethionineInduced Vascular Dementia in Rats. Biomed Res Int. 2022:7222590.
* Sun H et al. (2021) Retinol exerts therapeutic effect on myocardial infarction through regulation of immune inflammatory cells and Cx43 expression. Trop. J. Pharma. Res. 20(5):961-966.
* Saleh SA (2021) Possible Protective Effect of Endothelin-1 Receptor Antagonist on Renal Impairment in Type 2 Diabetic Rats. Bull. Egypt. Soc. Physiol. Sci. 41(2):242-257.
* Offor SJ et al. (2021) Hepato-Renal Effect Of Solanum Anomalum Thonn. Ex. Schumach Fruit Extracts on Lead-Exposed Albino Rats. Discovery Phytomedicine. 8(2):56-66.
* Habib CN et al. (2022) The potential neuroprotective effect of diosmin in rotenone-induced model of Parkinson's disease in rats. Eur J Pharmacol. 914:174573.
* Khodir S et al. (2021) Protective Potential of Ginseng and/or Coenzyme Q10 on Doxorubicin-induced Testicular and Hepatic Toxicity in Rats. Maced J Med Sci. 9(A):993-1005.
* Hazzaa SM et al. (2021) Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord. J Immunoassay Immunochem. 2021 Apr 26;1-24.
* Younis NN et al. (2020) Modulation of NADPH oxidase and Nrf2/HO-1 pathway by vanillin in cisplatin-induced nephrotoxicity in rats. J Pharm Pharmacol. 72(11):1546-1555.
* Faid SM (2020) Potential protective role of Melilotus officinalis extract against Cisplatin-induced cardiac and pulmonary toxicities in rats. African J. Biol. Sci. 16 (1):233-244.
* Ainosah RH et al. (2020) The effects of ursodeoxycholic acid on sepsis-induced cholestasis management in an animal model. J Taibah Univ Med Sci. 15(4):312-320.
* Elhadidy ME et al. (2018) Protective effect of ashwagandha (Withania somnifera) against neurotoxicity induced by aluminum chloride in rats. Asi. Pac. J. Trop. Biomed. 8(1):59-66.
* Eltahawy NA et al. (2017) Synergistic effect of aluminum and ionizing radiation upon ultrastructure, oxidative stress and apoptotic alterations in Paneth cells of rat intestine. Environ Sci Pollut Res Int. 24(7):6657-6666.
* Abdel-Razek HA et al. (2017) Effect of exercise and melatonin on fructose-induced hepatic dysfunction in a metabolic syndrome rat model. Menoufia Med. J. 30(1):286-296.
* Moosavi SJ et al. (2015) Protective effect of Ferula gummosa hydroalcoholic extract against nitric oxide deficiency-induced oxidative stress and inflammation in rats renal tissues. Clin Exp Hypertens. 37(2):136-41
* Abbas AM (2016) Cardioprotective effect of resveratrol analogue isorhapontigenin versus omega-3 fatty acids in isoproterenol-induced myocardial infarction in rats. J Physiol Biochem. 72(3):469-84.
* Chiu WC et al. (2014) Auricularia polytricha aqueous extract supplementation decreases hepatic lipid accumulation and improves antioxidative status in animal model of nonalcoholic fatty liver. Biomedicine (Taipei). 4(2):12.
* Saleh OS et al. (2013) Protective effects of propolis on gammairradiated nigella sativa extractinduced blood and immune changes in wistar rats. American Journal of Biochemistry and Biotechnology, 9 (2): 162-171
* Orsu P et al. (2013) Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats.J Neural Transm (Vienna). 120(8):1217-23.
* Omayma AR (2013) Effect of Probiotic Fermented Soy Milk and Gamma Radiation on Nitrosourea-Induced Mammary Carcinogenesis. Nature and Science 11(11):35-42
* Ali EN et al. (2013) EVALUATION OF SELENIUM NANOPARTICLES AS A POTENTIAL CHEMOPREVENTIVE AGENT AGAINST LUNG CARCINOMA. Int. J. Pharm.Bio. Chem Sci. 2(4):38-46.
* Eltahawy N et al. (2012) Effectiveness of Punica granatum juice in ameliorating oxidative damage and ultrastructural changes in Paneth cells of rat intestine. J. Pharm. Bio. Sci. 4(2):25-31.
* Terra X et al. (2011) FABP 4 is associated with inflammatory markers and metabolic syndrome in morbidly obese women. Eur J Endocrinol. 164(4):539-547
* Chou YH (2011) Effects of Auricularia polytricha extracts on improving liver damage in rats with nonalcoholic fatty liver disease. China medical university.
