Human Factor IX (Factor 9) ELISA Kit

Transplacental delivery of factor IX Fc-fusion protein ameliorates bleeding phenotype of newborn hemophilia B mice.

• https://pubmed.ncbi.nlm.nih.gov/39181162/
• Fuminori Sakurai, Shunsuke Iizuka, ..., Hiroyuki Mizuguchi (2024). Journal of controlled release : official j…. 2024 Aug 24

Selective Microvascular Tissue Transfection Using Minicircle DNA for Systemic Delivery of Human Coagulation Factor IX in a Rat Model Using a Therapeutic Flap

• https://pubmed.ncbi.nlm.nih.gov/34757962/#affiliation-1
• Than PA et al. (2022). Plast Reconstr Surg. 149(1):117-129

Endoscopic-mediated, biliary hydrodynamic injection mediating clinically relevant levels of gene delivery in pig liver

• https://pubmed.ncbi.nlm.nih.gov/34197834/
• Robert L Kruse, Yuting Huang, ..., Vivek Kumbhari (2021). Gastrointestinal endoscopy. 2021 Jun 29

CRISPR/Cas9-mediated gene correction in hemophilia B patient-derived iPSCs.

• https://pubmed.ncbi.nlm.nih.gov/31664646/
• Satoshi Morishige, Shinichi Mizuno, ..., Koji Nagafuji (2020). International journal of hematology. 2020 Aug 10

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

• https://www.nature.com/articles/s41467-018-04221-9
• A Roth, SP Maher, AJ Conway, R Ubalee...- Nature..., 2018 - nature.com

Plasma Proteome Analyses of Experimental Human and Murine Thyroid Disease Models

• https://epub.ub.uni-greifswald.de/frontdoor/deliver/index/docId/2118/file/Dissertation_Beatrice_Engelmann.pdf
• Engelmann B (2018). Ernst Moritz Arndt University of Greifswald. Dessertation.

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

• https://pubmed.ncbi.nlm.nih.gov/29884783/
• Alison Roth, Steven P. Maher, ..., John H. Adams (2018). Nature Communications. 2018 May 09

Systemic delivery of factor IX messenger RNA for protein replacement therapy

• https://www.pnas.org/doi/pdf/10.1073/pnas.1619653114
• Ramaswamya S et al. (2017). Proc Natl Acad Sci USA. 114(10):E1941-E1950.

Neonatal Gene Therapy for Hemophilia B by a Novel Adenovirus Vector Showing Reduced Leaky Expression of Viral Genes

• https://pubmed.ncbi.nlm.nih.gov/28828393/
• Shunsuke Iizuka, Fuminori Sakurai, ..., Hiroyuki Mizuguchi (2017). Molecular Therapy. Methods & Clinical Deve…. 2017 Jul 08

First case report of hemophilia B Leyden in Japan.

• https://pubmed.ncbi.nlm.nih.gov/28168417/
• Atsuki Yamashita, Chiai Nagae, ..., Masashi Taki (2017). International journal of hematology. 2017 Jul 07

Biodegradable hydrophilic carriers for the oral delivery of hematological factor IX for hemophilia B treatment.

• https://pubmed.ncbi.nlm.nih.gov/27863665/
• Sarena D Horava, Katie J Moy, Nicholas A Peppas (2017). International Journal of Pharmaceutics. 2017 Apr 14

Systemic delivery of factor IX messenger RNA for protein replacement therapy

• https://pubmed.ncbi.nlm.nih.gov/28202722/
• Suvasini Ramaswamy, Nina Tonnu (2017). Proceedings of the National Academy of Sci…. 2017 Feb 15

Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

• http://www.nature.com/gt/journal/v23/n10/full/gt201646a.html
• DeRosa F et al. (2016). Gene Therapy 23:699-

Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

• https://pubmed.ncbi.nlm.nih.gov/27356951/
• F DeRosa, B Guild, ..., M W Heartlein (2016). Gene therapy. 2016 Oct 01

Design of pH-Responsive Biomaterials to Enable the Oral Route of Hematological Factor IX

• https://pubmed.ncbi.nlm.nih.gov/26883955/
• Sarena D. Horava, Nicholas A. Peppas (2016). Annals of biomedical engineering. 2016 Feb 16

Lipid formulations for delivery of messenger rna

• http://www.google.com.pr/patents/US20150140070
• Heartlein M et al. (2015). Patents: US 20150140070 A1.

Development of an efficient human hepatocyte culture platform for assessing novel therapeutic efficacy against Plasmodium liver parasites

• https://digitalcommons.usf.edu/cgi/viewcontent.cgi?article=6459&context=etd
• Maher SP (2014). University of South Florida. Graduate Theses and Dissertations.

Mrna therapeutic compositions and use to treat diseases and disorders

• http://www.google.com/patents/WO2014152940A1?cl=en
• Heartlein M (2014). Patent application:WO2014152940 A1

Lipidic nanoparticles for mrna delivering

• http://www.google.com/patents/WO2014089486A1?cl=en
• Derosa F et al.(2014). Patent application:WO2014089486 A1

Lipid nanoparticle compositions and methods for mrna delivery

• http://www.google.com/patents/WO2012170930A1?cl=en
• Guild BC et al. (2012). Patent Application WO2012170930 A1

Early Detection of Malignant Pleural Mesothelioma in Asbestos-Exposed Individuals with a Noninvasive Proteomics-Based Surveillance Tool

• https://pubmed.ncbi.nlm.nih.gov/23056237/
• Rachel M. Ostroff, Michael R. Mehan, ..., Thomas Behrens (2012). PLoS ONE. 2012 Oct 03

Long-Acting Coagulation Factors and Methods of Producing Same

• http://www.freepatentsonline.com/8759292.html
• Fima UE et al. (2010). Patent No: US 8476234 B2

Sex hormones affect the production of recombinant Factor IX in CHO and HEK-293 cell lines

• https://pubmed.ncbi.nlm.nih.gov/18581062/#affiliation-1
• Dadehbeigi N et al. (2008). Biotechnol Lett. 30(11):1909-12

Sex hormones affect the production of recombinant Factor IX in CHO and HEK-293 cell lines

• https://pubmed.ncbi.nlm.nih.gov/18581062/
• Nazanin Dadehbeigi, Seyed Nasser Ostad, ..., Mohammad Hossein Ghahremani (2008). Biotechnology Letters. 2008 Jun 26