Name: Human Plasminogen Activator Inhibitor-1 (PAI-1) ELISA Kit
Brand: AssayMax&trade; ELISA Kits
SKU: EP1100-1
Availability: InStock

Additional information

Format	Sandwich ELISA
Entrez Gene	5054
Components	Biotinylated Human PAI-1 Antibody, Chromogen Substrate (1x), Human PAI-1 Microplate, Human PAI-1 Standard, MIX Diluent Concentrate (10x), Sealing Tapes, SP Conjugate (100x), Standard Diluent (1x), Stop Solution (1x), Wash Buffer Concentrate (20x)
TIme	4 hours
Sensitivity	15 pg/ml
Range	0.039 – 2.5 ng/ml
Samples Type	CSF, Plasma, Serum
Associated Disease	Cancer
Species	Human
UniProt	P05121
Storage	Refer to component labels for details
Plex	1
Usage	For Research Use Only, Not To Be Used For Diagnostic Purposes

Publications

"* Abolarin AT et al. (2022) Evaluating the effect of antidiabetic treatment on haemostatic and fibrinolytic parameters among type 2 diabetics in Ilorin, Nigeria. IBOM MEDICAL JOURNAL. 15(3): 252-258.
"* Sabouni R et al. (2021) Drospirenone effects on the plasminogen activator system in immortalized human endometrial endothelial cells. Reprod Sci. 28(7):1974-1980.
"* Nakano T et al. (2021) Arsenite Inhibits Tissue-Type Plasminogen Activator Synthesis through NRF2 Activation in Cultured Human Vascular Endothelial EA.hy926 Cells. Int J Mol Sci. 22(2):739.
"* Nagelkirk PR et al.(2021) Regular Resistance Training Enhances Fibrinolytic Potential but Does Not Affect Coagulation. Med Sci Sports Exerc. 53(11):2318-2323.
"* Kumar (2021) Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina. Cardiol Res Pract. 2021:5551031
"* Hara T et al. (2021) Cadmium induces plasminogen activator inhibitor-1 via Smad2/3 signaling pathway in human endothelial EA. hy926 cells. J.Toxicol.Sci. 46(5):249-253.
"* Wasiak S et al. (2020) Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease. Cardiovasc Ther. 2020:9397109
"* Takada T et al. (2020) Nobiletin represses change in the levels of blood coagulation markers in the LPS-induced rat DIC model. Functional Foods in Health and Disease. 10(9): 397-406.
"* Sackett JR et al. (2020) Hemostatic Adaptations to High Intensity Interval Training in Healthy Adult Men. Int J Sports Med. 41(12):867-872.
"* Bhatia A (2020) Endothelial dysfunction in children with frequently relapsing and steroid-resistant nephrotic syndrome. Asi J Pediatric Nephrology. 3(1):4-9.
"* Schmitt FCF et al. (2019) Acute fbrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study. Ann. Intensive Care. 9:19.
"* Ositadinma IM et al. (2019) Relationship among HbA1c and Some Markers of Endothelial Damage in Type 2 Diabetes Mellitus. International Blood Research & Reviews. 9(2):1-6
"* Siennicka A et al. (2018) Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro. Biomed Res Int. 2018: 3205324.
"* Elmoamly S and Afif A (2018) Can biomarkers of coagulation, platelet activation, and inflammation predict mortality in patients with hematological malignancies? Hematology. 23(2):89-95
"* Bodur S et al. (2018) The effects of different therapeutic modalities on cardiovascular risk factors in women with polycystic ovary syndrome: A random?zed controlled study. Taiwan J Obstet Gynecol. 57(3):411-416
"* Minomo H et al. (2017) Establishment of disseminated intravascular coagulation (DIC) modelby a single iv administration of Escherichia coli-derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of itspathophysiological status. J Pharmacol Sci. 133(2):88-95
"* Elci E et al. (2017) Evaluation of cardiac risk marker levels in obese and non-obese patients with polycystic ovaries. Gynecol Endocrinol. 33(1):43-47.
"* Zhou Y et al. (2016) Intervention of chlorogenic acid, caffeic acid and ferulic acid on the expression of inflammation-related molecules in endothelial cells caused by complement bypass activation. Chi.Pharma. Bulletin. 32(12): 1723-1728.
"* Van Epps P et al. (2016) Frailty has a stronger association with inflammation than age in older veterans. Immun Ageing. 2016 Oct 19;13:27. eCollection 2016
"* Ajibola SO et al. (2016) Utility of a single mid-trimester measurement of plasminogen activator Type 1 and fibronectin to predict preeclampsia in pregnancy. Nigerian Medical Journal 57 (4):213-216
"* Tazawa H et al. (2015) A microfluidic cell culture system for monitoring of sequential changes in endothelial cells after heat stress. Thromb Res. 136(2):328-34.
"* Schilder L et al. (2015) Coagulation, fibrinolysis and inhibitors in failing filters during continuous venovenous haemofiltration in critically ill patients with acute kidney injury: effect of anticoagulation modalities. Blood Purif. 39:297-305.
"* Mousavi M et al. (2015) Effects of Selenium Supplementation on Soluble FMS-Like Tyrosine Kinase-1 and Glutathione Peroxidase Levels and the Plasminogen Activator Inhibitor-1: Plasminogen Activator Inhibitor-2 Ratio in Pregnant Women. Shiraz E-Med J. 16(3): e21596.
"* Wang Y (2014) Association of the Plasminogen Activator Inhibitor-1 (PAI-1) Gene -675 4G/5G and -844 A/G Promoter Polymorphism with Risk of Keloid in a Chinese Han Population. Med Sci Monit. 20:2069-73
"* Tugcu D at al. (2014) Plasma Levels of Plasminogen Activator Inhibitor Type 1 and Vitronectin in Children With Cancer
"* Topcuoglu A et al. (2014) Effects of hormone replacement therapy on plasma and tissue fibrinolytic activity in a rat model of surgically induced menopause. Clin Invest Med. 2014 Apr 1;37(2):E85-92
"* Gavriilaki E et al. (2014) Increased thrombotic and impaired fibrinolytic response to acute exercise in patients with essential hypertension: The effect of treatment with an angiotensin II receptor blocker. J. Hum. Hypertens. 28(10):606-609.
"* Erem C et al. (2014) Comparison of Eff ects of Gliclazide, Metformin and Pioglitazone Monotherapies on Glycemic Control and Cardiovascular Risk Factors in Patients with Newly Diagnosed Uncontrolled Type 2 Diabetes Mellitus. Exp Clin Endocrinol Diabetes. 122(5):295-302.
"* Akkok B et al. (2014) Pleural effusion and plasma levels of fibrinolytic parameters in tuberculosis pleurisy and contribution to the diagnosis. Eurasian J Pulmonol. 16: 84-88
"* Yusuf J et al. (2015) Effect of heart rate control on coagulation status in patients of rheumatic mitral stenosis with atrial fibrillation-A pilot study. Indian Heart J. 67 Suppl 2(Suppl 2):S40-5.
"* Woodson SE at al. (2013) Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes. Virus Res. 175(2):155-9
"* To M et al. (2013) Sputum Plasminogen Activator Inhibitor-1 Elevation by Oxidative Stress-Dependent Nuclear Factor-kappaB Activation in COPDPlasminogen Activator Inhibitor-1 Elevation in COPD. Chest. 144(2):515-21
"* Siennicka A et al. (2013) Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? J Physiol Pharmacol. 64(3):321-30
"* Nsimba MM et al. (2013) Effect of a Congolese herbal medicine used in sickle cell anemia on the expression of plasminogen activators in human coronary aortic endothelial cells culture. J Ethnopharmacol. 146(2):594-9
"* Liu YW et al. (2013) Association of Left Ventricular Longitudinal Strain with Mortality among Stable Hemodialysis Patients with Preserved Left Ventricular Ejection Fraction. Clin J Am Soc Nephrol. 8(9):1564-1574
"* Johansson PI et al. (2013) Blood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after trauma. J Emerg Trauma Shock. 6(3):171-5
"* Genet GF (2013) Trauma-Induced Coagulopathy: Standard Coagulation Tests, Biomarkers of Coagulopathy, and Endothelial Damage in Patients with Traumatic Brain Injury. J Neurotrauma. 30:301?306
"* Vilas D et al. (2012) Circadian Rhythms in the Efficacy of Intravenous Alteplase in Patients With Acute Ischemic Stroke and Middle Cerebral Artery Occlusion. Chronobiol Int. 29(10):1383-9.
"* Ostrowski SR et al. (2012) High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study. Scand J Trauma Resusc Emerg Med. 2012 Apr 10;20:27
"* Johansson PI et al. (2012) High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality. J Thromb Haemost. 10(2):207-216
"* Ferro M et al. (2012) PLASMATIC SIL 6R/IL-6 RATIO AS A POTENTIAL PREDICTOR OF HIGH GLEASON SUM AT RADICAL PROSTATECTOMY. ANTICANCER RESEARCH 32: 1843-1966
"* Ostrowski SR et al. (2011) Thrombelastography and biomarker profiles in acute coagulopathy of trauma: A prospective study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 19:64
"* Mollmark J et al. (2011) Antiangiogenic Activity of rPAI-123 Promotes Vasa Vasorum Regression in Hypercholesterolemic Mice Through a Plasmin-Dependent Mechanism. Circ Res. 108(12):1419-1428
"* Krysiak R and Okopien B (2011) Haemostatic effects of simvastatin in subjects with impaired glucose tolerance. Intern Med J. 41(6):473-481
"* Johansson PI et al. (2011) Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study. Critical Care 15(6):R272
"* Cenni E et al. (2011) Idiopathic and secondary osteonecrosis of the femoral head show different thrombophilic changes and normal or higher levels of platelet growth factors. Acta Orthopaedica 82 (1): 42-49
"* Akanji AO et al. (2011) Determinants of blood levels of some thrombogenic biomarkers in healthy Arab adolescent subjects. Clin Chem Lab Med. 49(10):1681-90
"* Yen GC et al. (2010) Effects of Polyphenolic Compounds on Tumor Necrosis Factor-alpha (TNF-alpha)-Induced Changes of Adipokines and Oxidative Stress in 3T3-L1 Adipocytes. J Agric Food Chem. 59(2):546-551
"* Tuttolomondo A et al. (2010) Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke. Atherosclerosis. 213(1):311-8.
"* Turfaner N et al. (2010) Ezetimibe Therapy and Its Influence on Oxidative Stress and Fibrinolytic Activity. South Med J. 103:428-433
"* Suzuki N et al. (2010) GnRH receptor and peritoneal plasmin activity. Gynecol Endocrinol. 26(9):669-672
"* Sutoh T et al. (2010) Nafamostat Mesilate (FUT-175) Inhibits Cell Growth and Invasion of Malignant Pleural Mesothelioma Cell Line, MSTO-211H. Hirosaki Med. J. 61:19-25
"* Sonmez M et al. (2010) Treatment related changes in antifibrinolytic activity in patients with polycythemia vera. Hematology. 15(6):391-339
"* Sandra D et al. (2010) Downregulation of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 by grape seed proanthocyanidin extract. Phytomedicine 17(1): 42-46
"* Kajiwara N et al. (2010) Activation of human mast cells through the platelet-activating factor receptor. J Allergy Clin Immunol. 125(5):1137-1145.e6.
"* Jiang Y et al. (2010) Urokinase-type plasminogen activator system and human cationic antimicrobial protein 18 in serum and induced sputum of patients with chronic obstructive pulmonary disease. Respirology. 15(6):939-946.
"* Casas-Agustench P et al. (2010) Nuts, inflammation and insulin resistance. Asia Pac J Clin Nutr 19(1):124-130.
"* Tso TK and Huang WN (2009) Elevation of fasting insulin and its association with cardiovascular disease risk in women with systemic lupus erythematosus.Rheumatol Int. 29(7):735-42.
"* Tabak O et al. (2009) Hypertension and hemostatic/fibrinolytic balance disorders. Clin Invest Med. 32(6):E285
"* Oral B. et al. (2009) Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome. Gynecol Endocrinol 25:110-116
"* Muto S et al. (2009) INHIBITOR OF PAI-1 PRODUCTION. USPTO Patent Application 20090239868
"* Masuko K et al. (2009) A suppressive effect of prostaglandin E2 on the expression of SERPINE1/plasminogen activator inhibitor-1 in human articular chondrocytes: An in vitro pilot study. Open Access Rheumatol. 1: 9-15
"* Markosyan N and Duffy DM (2009) Prostaglandin E2 acts via multiple receptors to regulate plasminogen-dependent proteolysis in the primate periovulatory follicle. Endocrinology. 150(1):435-44
"* Sato H et al. (2008) The inhibitory effect of connexin 32 gene on metastasis in renal cell carcinoma. Mol Carcinog. 47(6):403-409
"* Oszajca K et al. (2008) Effect of oxidative stress on the expression of t-PA, u-PA, u-PAR, and PAI-1 in endothelial cells. Biochem Cell Biol. 86(6):477-486
"* Langouche L et al. (2008) Effect of insulin therapy on coagulation and fibrinolysis in medical intensive care patients. Crit Care Med. 36(5):1475-1480
"* He WJ et al. (2008) Activated protein C ratio, plasma tissue factor activity and activated factor VII in Chinese patients with coronary heart disease. Eur J Med Res. 13:47-51
"* Demirel A et al. (2008) Is Familial Mediterranean Fever a thrombotic disease or not? Eur J Pediatr. 167(3):279-285
"* Yang CC et al. (2007) In vitro regulation of adipogenesis: tunable engineered tissues. J Tissue Eng Regen Med. 1(2):146-153
"* Wei JL et al. (2007) Synergistic effects of pravastatin and pioglitazone in renal tubular epithelial cells induced by transforming growth factor-beta1. Cell Biol Int. 31(5):451-458
"* Katsutani M et al. (2007) Glucose-Based PD Solution, But Not Icodextrin-Based PD Solution, Induces Plasminogen Activator Inhibitor-1 and Tissue-Type Plasminogen Activator in Human Peritoneal Mesothelial Cells via ERK1/2. Ther Apher Dial. 11(2): 94-100.
"* Yoshida H et al. (2006) Interleukin-1beta enhances the angiotensin-induced expression of plasminogen activator inhibitor-1 through angiotensin receptor upregulation in human astrocytes. Brain Res. 16;1073-1074:38-47
"* Roth GA et al. (2006) Infection with a periodontal pathogen induces procoagulant effects in human aortic endothelial cells. Journal of Thrombosis and Haemostasis 4(10):2256-2261
"* Drinane MC et al. (2006) Plasminogen and plasmin activity in patients with coronary artery disease. J Thromb Haemost. 4(6):1288-1295
"* Inoue M et al. (2005) Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis. Oncol Rep. 14(6):1445-1451
"* Oka N et al. (2003) Amiloride and Urinary Trypsin Inhibitor Inhibit Urothelial Cancer Invasion. Eur Urol. 44(6):737-741
"* Kimura D et al. (2002) Hypoxia enhances the expression of plasmino activator inhibitors-1 in human lung cancer cells, EBC-1. Tohoku J. Exp. Med. 196:259-267.

Human Plasminogen Activator Inhibitor-1 (PAI-1) ELISA Kit

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