Human Plasminogen Activator Inhibitor-1 (PAI-1) ELISA Kit

$407.00

Catalog Number: EP1100-1

This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Product Size:96 Well Plate

Catalog Number. EP1100-1 Categories: , , Tag: Brand:

Additional information

Format

Sandwich ELISA

Entrez Gene

5054

Components

Biotinylated Human PAI-1 Antibody, Chromogen Substrate (1x), Human PAI-1 Microplate, Human PAI-1 Standard, MIX Diluent Concentrate (10x), Sealing Tapes, SP Conjugate (100x), Standard Diluent (1x), Stop Solution (1x), Wash Buffer Concentrate (20x)

TIme

4 hours

Sensitivity

15 pg/ml

Range

0.039 – 2.5 ng/ml

Samples Type

CSF, Plasma, Serum

Associated Disease

Cancer

Species

Human

UniProt

P05121

Storage

Refer to component labels for details

Plex

1

Usage

For Research Use Only, Not To Be Used For Diagnostic Purposes

Documentation

Publications (92 results)

Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.

Sputum plasminogen activator inhibitor-1 elevation by oxidative stress-dependent nuclear factor-κB activation in COPD

  • https://www.sciencedirect.com/science/article/pii/S0012369213605279
  • M To, D Takagi, K Akashi, I Kano, K Haruki, PJ Barnes… - Chest, 2013 - Elsevier
  • Background Plasminogen activator inhibitor-1 (PAI-1) is an important regulator of fibrinolysis at sites of vascular injury and thrombus formation. Recently, sputum PAI-1 was reported to …

Idiopathic and secondary osteonecrosis of the femoral head show different thrombophilic changes and normal or higher levels of platelet growth factors

Pleural Effusion and Plasma Levels of Fibrinolytic Parameters in Tuberculosis Pleurisy and Contribution to the Diagnosis.

Coagulation, fibrinolysis and inhibitors in failing filters during continuous venovenous hemofiltration in critically Ill patients with acute kidney injury: effect of …

  • https://karger.com/bpu/article/39/4/297/48520
  • L Schilder, SA Nurmohamed, PM ter Wee… - Blood …, 2015 - karger.com
  • Introduction: The mechanisms of early filter failure and clotting with different anticoagulation modalities during continuous venovenous hemofiltration (CVVH) are largely unknown. …

Tüberküloz Plörezide Fibrinolitik Parametrelerin Plevra Sıvısı, Plazmadaki Düzeyleri ve Tanıya Katkısı

Comparison of effects of gliclazide, metformin and pioglitazone monotherapies on glycemic control and cardiovascular risk factors in patients with newly diagnosed …

Regular resistance training enhances fibrinolytic potential but does not affect coagulation

Comparison of the effects of intensive insulin treatment modalities on cardiovascular biomarkers in type 1 diabetes mellitus

  • https://www.sciencedirect.com/science/article/pii/S1871402115000399
  • S Cetinkalp, C Felekoglu, M Karadeniz… - Diabetes & Metabolic …, 2015 - Elsevier
  • Aim To evaluate effects of intensive insulin treatment modalities on cardiovascular biomarkers in patients with type 1 diabetes mellitus (T1DM). Materials and methods A total of 25 …

Plasma Levels of Plasminogen Activator Inhibitor Type 1 and Vitronectin in Children With Cancer

  • https://journals.sagepub.com/doi/abs/10.1177/1076029614531450
  • D Tugcu, O Devecioglu, A Unuvar… - Clinical and Applied …, 2016 - journals.sagepub.com
  • Background: The plasminogen activator system controls intravascular fibrin deposition; besides, it also participates in a wide variety of physiologic and pathologic processes, including …

Comparison of the effects of intensive insulin treatment

Evaluation of thrombomodulin/thrombin activatable fibrinolysis inhibitor function in plasma using tissue-type plasminogen activator-induced plasma clot lysis …

  • https://www.sciencedirect.com/science/article/pii/S2475037924001523
  • T Urano, Y Sano, Y Suzuki, M Okada, H Sano… - Research and Practice …, 2024 - Elsevier
  • Background Thrombin activatable fibrinolysis inhibitor (TAFI) is one of the most important physiological fibrinolysis inhibitors. Its inhibitory efficacy under physiological conditions …

AMP-activated protein kinase, Sirtuin 1, and p53 interactions in HEPG2 cells

Human Plasminogen Activator Inhibitor-1

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İnflamatuar barsak hastalığında erken aterosklerozun değerlendirilmesi

* Abolarin AT et al. (2022) Evaluating the effect of antidiabetic treatment on haemostatic and fibrinolytic parameters among type 2 diabetics in Ilorin, Nigeria. IBOM MEDICAL JOURNAL. 15(3): 252-258.

* Sabouni R et al. (2021) Drospirenone effects on the plasminogen activator system in immortalized human endometrial endothelial cells. Reprod Sci. 28(7):1974-1980.

* Nakano T et al. (2021) Arsenite Inhibits Tissue-Type Plasminogen Activator Synthesis through NRF2 Activation in Cultured Human Vascular Endothelial EA.hy926 Cells. Int J Mol Sci. 22(2):739.

* Kumar (2021) Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina. Cardiol Res Pract. 2021:5551031

* Hara T et al. (2021) Cadmium induces plasminogen activator inhibitor-1 via Smad2/3 signaling pathway in human endothelial EA. hy926 cells. J.Toxicol.Sci. 46(5):249-253.

* Wasiak S et al. (2020) Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease. Cardiovasc Ther. 2020:9397109

* Takada T et al. (2020) Nobiletin represses change in the levels of blood coagulation markers in the LPS-induced rat DIC model. Functional Foods in Health and Disease. 10(9): 397-406.

* Sackett JR et al. (2020) Hemostatic Adaptations to High Intensity Interval Training in Healthy Adult Men. Int J Sports Med. 41(12):867-872.

* Bhatia A (2020) Endothelial dysfunction in children with frequently relapsing and steroid-resistant nephrotic syndrome. Asi J Pediatric Nephrology. 3(1):4-9.

* Schmitt FCF et al. (2019) Acute fbrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study. Ann. Intensive Care. 9:19.

* Ositadinma IM et al. (2019) Relationship among HbA1c and Some Markers of Endothelial Damage in Type 2 Diabetes Mellitus. International Blood Research & Reviews. 9(2):1-6

* Siennicka A et al. (2018) Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro. Biomed Res Int. 2018: 3205324.

* Elmoamly S and Afif A (2018) Can biomarkers of coagulation, platelet activation, and inflammation predict mortality in patients with hematological malignancies? Hematology. 23(2):89-95

* Bodur S et al. (2018) The effects of different therapeutic modalities on cardiovascular risk factors in women with polycystic ovary syndrome: A random?zed controlled study. Taiwan J Obstet Gynecol. 57(3):411-416

* Minomo H et al. (2017) Establishment of disseminated intravascular coagulation (DIC) modelby a single iv administration of Escherichia coli-derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of itspathophysiological status. J Pharmacol Sci. 133(2):88-95

* Elci E et al. (2017) Evaluation of cardiac risk marker levels in obese and non-obese patients with polycystic ovaries. Gynecol Endocrinol. 33(1):43-47.

* Zhou Y et al. (2016) Intervention of chlorogenic acid, caffeic acid and ferulic acid on the expression of inflammation-related molecules in endothelial cells caused by complement bypass activation. Chi.Pharma. Bulletin. 32(12): 1723-1728.

* Van Epps P et al. (2016) Frailty has a stronger association with inflammation than age in older veterans. Immun Ageing. 2016 Oct 19;13:27. eCollection 2016

* Ajibola SO et al. (2016) Utility of a single mid-trimester measurement of plasminogen activator Type 1 and fibronectin to predict preeclampsia in pregnancy. Nigerian Medical Journal 57 (4):213-216

* Tazawa H et al. (2015) A microfluidic cell culture system for monitoring of sequential changes in endothelial cells after heat stress. Thromb Res. 136(2):328-34.

* Schilder L et al. (2015) Coagulation, fibrinolysis and inhibitors in failing filters during continuous venovenous haemofiltration in critically ill patients with acute kidney injury: effect of anticoagulation modalities. Blood Purif. 39:297-305.

* Mousavi M et al. (2015) Effects of Selenium Supplementation on Soluble FMS-Like Tyrosine Kinase-1 and Glutathione Peroxidase Levels and the Plasminogen Activator Inhibitor-1: Plasminogen Activator Inhibitor-2 Ratio in Pregnant Women. Shiraz E-Med J. 16(3): e21596.

* Wang Y (2014) Association of the Plasminogen Activator Inhibitor-1 (PAI-1) Gene -675 4G/5G and -844 A/G Promoter Polymorphism with Risk of Keloid in a Chinese Han Population. Med Sci Monit. 20:2069-73

* Tugcu D at al. (2014) Plasma Levels of Plasminogen Activator Inhibitor Type 1 and Vitronectin in Children With Cancer

* Topcuoglu A et al. (2014) Effects of hormone replacement therapy on plasma and tissue fibrinolytic activity in a rat model of surgically induced menopause. Clin Invest Med. 2014 Apr 1;37(2):E85-92

* Gavriilaki E et al. (2014) Increased thrombotic and impaired fibrinolytic response to acute exercise in patients with essential hypertension: The effect of treatment with an angiotensin II receptor blocker. J. Hum. Hypertens. 28(10):606-609.

* Akkok B et al. (2014) Pleural effusion and plasma levels of fibrinolytic parameters in tuberculosis pleurisy and contribution to the diagnosis. Eurasian J Pulmonol. 16: 84-88

* Yusuf J et al. (2015) Effect of heart rate control on coagulation status in patients of rheumatic mitral stenosis with atrial fibrillation-A pilot study. Indian Heart J. 67 Suppl 2(Suppl 2):S40-5.

* Woodson SE at al. (2013) Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes. Virus Res. 175(2):155-9

* To M et al. (2013) Sputum Plasminogen Activator Inhibitor-1 Elevation by Oxidative Stress-Dependent Nuclear Factor-kappaB Activation in COPDPlasminogen Activator Inhibitor-1 Elevation in COPD. Chest. 144(2):515-21

* Siennicka A et al. (2013) Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? J Physiol Pharmacol. 64(3):321-30

* Nsimba MM et al. (2013) Effect of a Congolese herbal medicine used in sickle cell anemia on the expression of plasminogen activators in human coronary aortic endothelial cells culture. J Ethnopharmacol. 146(2):594-9

* Liu YW et al. (2013) Association of Left Ventricular Longitudinal Strain with Mortality among Stable Hemodialysis Patients with Preserved Left Ventricular Ejection Fraction. Clin J Am Soc Nephrol. 8(9):1564-1574

* Johansson PI et al. (2013) Blood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after trauma. J Emerg Trauma Shock. 6(3):171-5

* Genet GF (2013) Trauma-Induced Coagulopathy: Standard Coagulation Tests, Biomarkers of Coagulopathy, and Endothelial Damage in Patients with Traumatic Brain Injury. J Neurotrauma. 30:301?306

* Vilas D et al. (2012) Circadian Rhythms in the Efficacy of Intravenous Alteplase in Patients With Acute Ischemic Stroke and Middle Cerebral Artery Occlusion. Chronobiol Int. 29(10):1383-9.

* Ostrowski SR et al. (2012) High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study. Scand J Trauma Resusc Emerg Med. 2012 Apr 10;20:27

* Johansson PI et al. (2012) High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality. J Thromb Haemost. 10(2):207-216

* Ferro M et al. (2012) PLASMATIC SIL 6R/IL-6 RATIO AS A POTENTIAL PREDICTOR OF HIGH GLEASON SUM AT RADICAL PROSTATECTOMY. ANTICANCER RESEARCH 32: 1843-1966

* Ostrowski SR et al. (2011) Thrombelastography and biomarker profiles in acute coagulopathy of trauma: A prospective study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 19:64

* Mollmark J et al. (2011) Antiangiogenic Activity of rPAI-123 Promotes Vasa Vasorum Regression in Hypercholesterolemic Mice Through a Plasmin-Dependent Mechanism. Circ Res. 108(12):1419-1428

* Krysiak R and Okopien B (2011) Haemostatic effects of simvastatin in subjects with impaired glucose tolerance. Intern Med J. 41(6):473-481

* Johansson PI et al. (2011) Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study. Critical Care 15(6):R272

* Cenni E et al. (2011) Idiopathic and secondary osteonecrosis of the femoral head show different thrombophilic changes and normal or higher levels of platelet growth factors. Acta Orthopaedica 82 (1): 42-49

* Akanji AO et al. (2011) Determinants of blood levels of some thrombogenic biomarkers in healthy Arab adolescent subjects. Clin Chem Lab Med. 49(10):1681-90

* Yen GC et al. (2010) Effects of Polyphenolic Compounds on Tumor Necrosis Factor-alpha (TNF-alpha)-Induced Changes of Adipokines and Oxidative Stress in 3T3-L1 Adipocytes. J Agric Food Chem. 59(2):546-551

* Tuttolomondo A et al. (2010) Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke. Atherosclerosis. 213(1):311-8.

* Turfaner N et al. (2010) Ezetimibe Therapy and Its Influence on Oxidative Stress and Fibrinolytic Activity. South Med J. 103:428-433

* Suzuki N et al. (2010) GnRH receptor and peritoneal plasmin activity. Gynecol Endocrinol. 26(9):669-672

* Sutoh T et al. (2010) Nafamostat Mesilate (FUT-175) Inhibits Cell Growth and Invasion of Malignant Pleural Mesothelioma Cell Line, MSTO-211H. Hirosaki Med. J. 61:19-25

* Sonmez M et al. (2010) Treatment related changes in antifibrinolytic activity in patients with polycythemia vera. Hematology. 15(6):391-339

* Sandra D et al. (2010) Downregulation of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 by grape seed proanthocyanidin extract. Phytomedicine 17(1): 42-46

* Kajiwara N et al. (2010) Activation of human mast cells through the platelet-activating factor receptor. J Allergy Clin Immunol. 125(5):1137-1145.e6.

* Jiang Y et al. (2010) Urokinase-type plasminogen activator system and human cationic antimicrobial protein 18 in serum and induced sputum of patients with chronic obstructive pulmonary disease. Respirology. 15(6):939-946.

* Casas-Agustench P et al. (2010) Nuts, inflammation and insulin resistance. Asia Pac J Clin Nutr 19(1):124-130.

* Tso TK and Huang WN (2009) Elevation of fasting insulin and its association with cardiovascular disease risk in women with systemic lupus erythematosus.Rheumatol Int. 29(7):735-42.

* Tabak O et al. (2009) Hypertension and hemostatic/fibrinolytic balance disorders. Clin Invest Med. 32(6):E285

* Oral B. et al. (2009) Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome. Gynecol Endocrinol 25:110-116

* Muto S et al. (2009) INHIBITOR OF PAI-1 PRODUCTION. USPTO Patent Application 20090239868

* Masuko K et al. (2009) A suppressive effect of prostaglandin E2 on the expression of SERPINE1/plasminogen activator inhibitor-1 in human articular chondrocytes: An in vitro pilot study. Open Access Rheumatol. 1: 9-15

* Markosyan N and Duffy DM (2009) Prostaglandin E2 acts via multiple receptors to regulate plasminogen-dependent proteolysis in the primate periovulatory follicle. Endocrinology. 150(1):435-44

* Sato H et al. (2008) The inhibitory effect of connexin 32 gene on metastasis in renal cell carcinoma. Mol Carcinog. 47(6):403-409

* Oszajca K et al. (2008) Effect of oxidative stress on the expression of t-PA, u-PA, u-PAR, and PAI-1 in endothelial cells. Biochem Cell Biol. 86(6):477-486

* Langouche L et al. (2008) Effect of insulin therapy on coagulation and fibrinolysis in medical intensive care patients. Crit Care Med. 36(5):1475-1480

* He WJ et al. (2008) Activated protein C ratio, plasma tissue factor activity and activated factor VII in Chinese patients with coronary heart disease. Eur J Med Res. 13:47-51

* Demirel A et al. (2008) Is Familial Mediterranean Fever a thrombotic disease or not? Eur J Pediatr. 167(3):279-285

* Yang CC et al. (2007) In vitro regulation of adipogenesis: tunable engineered tissues. J Tissue Eng Regen Med. 1(2):146-153

* Wei JL et al. (2007) Synergistic effects of pravastatin and pioglitazone in renal tubular epithelial cells induced by transforming growth factor-beta1. Cell Biol Int. 31(5):451-458

* Katsutani M et al. (2007) Glucose-Based PD Solution, But Not Icodextrin-Based PD Solution, Induces Plasminogen Activator Inhibitor-1 and Tissue-Type Plasminogen Activator in Human Peritoneal Mesothelial Cells via ERK1/2. Ther Apher Dial. 11(2): 94-100.

* Yoshida H et al. (2006) Interleukin-1beta enhances the angiotensin-induced expression of plasminogen activator inhibitor-1 through angiotensin receptor upregulation in human astrocytes. Brain Res. 16;1073-1074:38-47

* Roth GA et al. (2006) Infection with a periodontal pathogen induces procoagulant effects in human aortic endothelial cells. Journal of Thrombosis and Haemostasis 4(10):2256-2261

* Drinane MC et al. (2006) Plasminogen and plasmin activity in patients with coronary artery disease. J Thromb Haemost. 4(6):1288-1295

* Inoue M et al. (2005) Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis. Oncol Rep. 14(6):1445-1451

* Oka N et al. (2003) Amiloride and Urinary Trypsin Inhibitor Inhibit Urothelial Cancer Invasion. Eur Urol. 44(6):737-741

* Kimura D et al. (2002) Hypoxia enhances the expression of plasmino activator inhibitors-1 in human lung cancer cells, EBC-1. Tohoku J. Exp. Med. 196:259-267.

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