Human Thrombin-Antithrombin Complex (TAT) ELISA Kit

SARS-CoV-2 infection results in upregulation of Plasminogen Activator Inhibitor-1 and Neuroserpin in the lungs, and an increase in fibrinolysis inhibitors associated

• https://pmc.ncbi.nlm.nih.gov/articles/PMC10188457/pdf/JHA2-4-324.pdf
• KH Toomer, GF Gerber, Y Zhang, L Daou, M Tushek - , 2023 - Wiley Online Library
• Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection results in coagulation activation although it is usually not associated with consumption coagulopathy. D-

Thrombin activatable fibrinolysis inhibitor and thrombin-antithrombin-III-complex levels in patients with gastric cancer

• https://link.springer.com/article/10.1007/s13277-012-0403-6
• E Fidan, H Kavgaci, A Orem, M Yilmaz, B Yildiz - Tumor Biology, 2012 - Springer
• Levels of TAT were determined using an enzyme-linked immunosorbent assay kit (Assaypro, catalog no. ET1020-1; USA), according to the manufacturers instructions. Absorbance of

Higher thrombin-antithrombin III complex levels may indicate severe acute pancreatitis

• https://karger.com/ddi/article/36/3/244/79036
• S Fidan, M Erkut, AM Cosar, Y Yogun, A rem - Digestive , 2018 - karger.com
• Levels of TAT were determined using an enzyme-linked immunosorbent assay kit (Assaypro, catalog No. ET1020-1; Lot No.: 09591020, USA), according to the manufacturers

Coagulation, fibrinolysis and inhibitors in failing filters during continuous venovenous hemofiltration in critically Ill patients with acute kidney injury: effect of

• https://karger.com/bpu/article/39/4/297/48520
• L Schilder, SA Nurmohamed, PM ter Wee - Blood , 2015 - karger.com
• Introduction: The mechanisms of early filter failure and clotting with different anticoagulation modalities during continuous venovenous hemofiltration (CVVH) are largely unknown.

Thrombin activatable fibrinolysis inhibitor (TAFI) levels in hypertensive patients and a comparison of the effects of amlodipine and ramipril on TAFI levels

• https://www.tandfonline.com/doi/abs/10.3109/10641963.2012.702833
• G Ozkan, S Ulusoy, M Snmez - Clinical and , 2013 - Taylor & Francis
• Hypertension is associated with fibrinolysis abnormality. Thrombin-activatable fibrinolysis inhibitor (TAFI) is a novel molecule-linking coagulation and fibrinolysis. The aim of this study

Angiotensin II triggers neutrophil extracellular traps release linking thromboinflammation with essential hypertension

• https://insight.jci.org/articles/view/148668/version/1/pdf/render.pdf
• A Chrysanthopoulou, K Ritis, P Skendros - insight.jci.org
• The procedure was performed according to the manufacturers instructions (ET1020-1, Assaypro, St Charles, MO, USA) and as previously described (16, 22). Isolated NET

Graph theoretical design of biomimetic aramid nanofiber composites as insulation coatings for implantable bioelectronics

• https://link.springer.com/article/10.1557/s43577-021-00071-x
• Zhang H et al. (2021). MRS Bulletin. 46:576-587.
• No Snippet Provided

The role of Plasminogen Activator Inhibitor 1 in predicting sepsis-associated liver dysfunction: an observational study

• https://assets.researchsquare.com/files/rs-46756/v2/2c8156ae-2048-491a-acf9-44e40ec2bae3.pdf?c=1631870042.
• Niesobska EW et al. (2021). DOI: https://doi.org/10.21203/rs.3.rs-46756/v2.
• No Snippet Provided

Measuring serum prothrombin in patients treated with warfarin or direct oral anticoagulants

• https://pubmed.ncbi.nlm.nih.gov/34599901/#affiliation-1
• Kondo A et al. (2021). Clin Chim Acta. 523:224-230.
• No Snippet Provided

Endothelial dysfunction in obstructive sleep apnea patients

• https://link.springer.com/content/pdf/10.1007/s11325-021-02382-4.pdf
• Haranczyk M et al. (2021). Sleep Breathing.7 May 2021.
• No Snippet Provided

Cell Surface Functionalization with Heparin Conjugated Lipid to Suppress Blood Activation

• https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202008167.
• Asawa K et al. (2021). Adv. Func. Mat. 31(11).
• No Snippet Provided

Selective potassium uptake via biocompatible zeolite?polymer hybrid microbeads as promising binders for hyperkalemia

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498761/pdf/main.pdf
• Wang Z et al. (2020).Bioact Mater. 6(2):543-558.
• No Snippet Provided

Wang Z et al. (2020).Bioact Mater. 6(2):543-558.

• https://elibrary.ru/item.asp?id=42549965.
• Timoshenko OV et al. (2020). eLIBRARY ID: 42549965.
• No Snippet Provided

Increased perihematomal neuron autophagy and plasma thrombin?antithrombin levels in patients with intracerebral hemorrhage: An observational study

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775380/pdf/medi-98-e17130.pdf
• Wu C et al. (2019). Medicine (Baltimore). 98(39):e17130
• No Snippet Provided

Acute fbrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

• https://annalsofintensivecare.springeropen.com/track/pdf/10.1186/s13613-019-0499-6.pdf
• Schmitt FCF et al. (2019). Ann. Intensive Care. 9:19.
• No Snippet Provided

Rationally designed magnetic nanoparticles as anticoagulants for blood purification.

• https://pubmed.ncbi.nlm.nih.gov/29413611/#affiliation-1
• Zhao W et al. (2018)
• No Snippet Provided

REDD1/Autophagy Pathway Is Associated with Neutrophil-Driven IL-1 beta Inflammatory Response in Active Ulcerative Colitis

• https://www.jimmunol.org/content/jimmunol/200/12/3950.full.pdf
• Angelidou I et al. (2018). J Immunol. 200(12):3950-3961.
• No Snippet Provided

Preparation, characterization and biocompatibility evaluation of poly(diol cittate) blend polyethersulfone hemodialysis membranes

• https://core.ac.uk/download/pdf/199241955.pdf
• Zailani MZB (2017). University of Technology Malaysia. Thesis.
• No Snippet Provided

Neutrophil extracellular traps promote hypercoagulability in patients with sepsis

• https://www.researchgate.net/profile/Kejia-Kan/publication/308009487_Neutrophil_Extracellular_Traps_Promote_Hypercoagulability_in_Patients_With_Sepsis/links/5a7755ecaca2722e4df1023a/Neutrophil-Extracellular-Traps-Promote-Hypercoagulability-in-Patients-With-Sepsis.pdf
• Yang S et al. (2017). Shock. 47(2):132-139.
• No Snippet Provided

Super-Anticoagulant Heparin-Mimicking Hydrogel Thin Film Attached Substrate Surfaces to Improve Hemocompatibility

• https://www.researchgate.net/profile/Changsheng-Zhao-2/publication/308699424_Super-Anticoagulant_Heparin-Mimicking_Hydrogel_Thin_Film_Attached_Substrate_Surfaces_to_Improve_Hemocompatibility/links/5e06c9a292851c83649fd487/Super-Anticoagulant-Heparin-Mimicking-Hydrogel-Thin-Film-Attached-Substrate-Surfaces-to-Improve-Hemocompatibility.pdf
• He M et al. (2017). Macromol Biosci. 17:1600281. doi: 10.1002/mabi.201600281.
• No Snippet Provided

Histones stimulate von Willebrand factor release in vitro and in vivo

• http://www.haematologica.org/content/haematol/101/7/e277.full.pdf
• Lam FW et al. (2016). Haematologica. 101(7):e277-9
• No Snippet Provided

Layer by layer assembly of sulfonic poly (ether sulfone) as heparin-mimicking coatings: scalable fabrication of super-hemocompatible and antibacterial membranes

• https://pubmed.ncbi.nlm.nih.gov/32264490/
• Wang L et al. (2015). J Mater Chem B. 3(7):1391-1404.
• No Snippet Provided

Blood activation and compatibility on single-molecular-layer biointerfaces

• https://pubs.rsc.org/en/content/getauthorversionpdf/c4tb00555d
• Nie S et al. (2014). J Mater Chem B. 2(30):4911-4921.
• No Snippet Provided

Allowable values of different parameters of hemostatic system in physiological pregnancy

• http://new.kamld.kz/wp-content/uploads/2018/02/%D0%96%D1%83%D1%80%D0%BD%D0%B0%D0%BB-%D0%9B%D0%B0%D0%B1%D0%BE%D1%80%D0%B0%D1%82%D0%BE%D1%80%D0%BD%D0%B0%D1%8F-%D0%BC%D0%B5%D0%B4%D0%B8%D1%86%D0%B8%D0%BD%D0%B0_411_2014.pdf
• Momot AP et al. (2014). Kazakhstan Association of Medical Laboratory Diagnostics 4(11):49-59
• No Snippet Provided

Increased thrombotic and impaired fibrinolytic response to acute exercise in patients with essential hypertension: The effect of treatment with an angiotensin II receptor blocker

• https://www.nature.com/articles/jhh201418.pdf
• Gavriilaki E et al. (2014). J. Hum. Hypertens. 28(10):606-609.
• No Snippet Provided

Biologically inspired membrane design with a heparin-like interface: prolonged blood coagulation, inhibited complement activation, and bio-artificial liver related cell proliferation

• https://pubs.rsc.org/en/content/articlehtml/2013/bm/c3bm60165j
• Nie S et al. (2013). Biomater. Sci. 2:98-109.
• No Snippet Provided

Activation of coagulation, anti-coagulation, fibrinolysis and the complement system in patients with urticaria

• http://apjai.digitaljournals.org/index.php/apjai/article/viewFile/900/1098
• Zhu H et al. (2012). Asian Pac J Allergy Immunol 31:43-50
• No Snippet Provided

Thrombosis from a prothrombin mutation conveying antithrombin resistance

• http://www.nejm.org/doi/pdf/10.1056/NEJMoa1201994
• Miyawaki Y et al. (2012). N Engl J Med. 366(25):2390-2396
• No Snippet Provided

The short term effects of endovascular a neurysm repair (ever) on coagulation and cardiovascular morbidity and mortality in patients with infra-renal abdominal aortic aneurysms

• http://etheses.bham.ac.uk/3727/1/Davies_12_MD.pdf
• Davies R (2012)
• No Snippet Provided

Analysis of thrombin?antithrombin complex contents in plasma and hematoma fluid of hypertensive intracerebral hemorrhage patients after clot removal

• https://pubmed.ncbi.nlm.nih.gov/21244583/#affiliation-1
• Wu CH et al. (2011). Eur J Neurol. 18(8):1060-6
• No Snippet Provided

Quantitative plasma proteome analysis reveals aberrant level of blood coagulation-related proteins in nasopharyngeal carcinoma

• https://pubmed.ncbi.nlm.nih.gov/21376147/
• Peng PH et al. (2011). J Proteomics. 74(5):744-57
• No Snippet Provided

Monomeric CRP is prothrombotic and dissociates from circulating pentameric CRP on adhered activated platelets under flow

• http://cardiovascres.oxfordjournals.org/content/cardiovascres/92/2/328.full.pdf
• Molins B et al. (2011). Cardiovasc Res doi: 10.1093/cvr/cvr226
• No Snippet Provided

ALKALI TREATMENT OF MICROROUGH TITANIUM SURFACES AFFECTS MACROPHAGE/MONOCYTE ADHESION, PLATELET ACTIVATION AND ARCHITECTURE OF BLOOD CLOT FORMATION

• http://www.ecmjournal.org/journal/papers/vol021/pdf/v021a32.pdf
• Milleret V et al. (2011). European Cells and Materials 21:430-444
• No Snippet Provided

Association of Thrombotic and Fibrinolytic Factors with Severity of Culprit Lesion in Patients with Acute Coronary Syndromes Without ST Elevation

• https://pubmed.ncbi.nlm.nih.gov/20224507/
• Turker Y et al. (2010). South Med J. 103(4):289-294.
• No Snippet Provided

Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet

• http://onlinelibrary.wiley.com/doi/10.1111/j.1538-7836.2010.03976.x/epdf
• Li F et al. (2010). J Thromb Haemost. 8(10):2122-2132
• No Snippet Provided

THE ROLES OF PLASMA PROTEINS AND NEUTROPHILS IN MELANOMA METASTASIS.

• https://honors.libraries.psu.edu/files/final_submissions/623
• Godiska LM (2010)
• No Snippet Provided

Coagulation, fibrinolysis and inhibitors in failing filters during continuous venovenous haemofiltration in critically ill patients with acute kidney injury: effect of anticoagulation modalities

• https://pdfs.semanticscholar.org/695b/a0f85cc2808999b7a8b8cff99113d0f58f17.pdf
• Schilder L et al. (2015). Blood Purif. 39:297-305.
• No Snippet Provided

Promotion of Hypercoagulability in Antineutrophil Cytoplasmic Antibody Associated Vasculitis by C5a-Induced Tissue Factor Expressing Microparticles and Neutrophil Extracellular Traps

• https://onlinelibrary.wiley.com/doi/pdf/10.1002/art.39239.
• Huang YM et al. (2015). Arthritis Rheumatol. 67(10):2780-2790.
• No Snippet Provided

Self-anticoagulant sponge for whole blood auto-transfusion and its mechanism of coagulation factor inactivation.

• https://pubmed.ncbi.nlm.nih.gov/37573353/
• Tao Xu, Haifeng Ji, ..., Changsheng Zhao (2023). Nature Communications. 2023 Aug 14
• .. was subjected to centrifugation to obtain PPP after a 30-min incubation at 37 °C.. The concentration of generated thrombin wasmeasured using a Human Thrombin-Antithrombin Complex AssayMax ELISA Kit (Assay Pro, USA).. Mechanistic exploration of inactivation of coagulation factors by the sponges Detection of the activities ..

SARS‐CoV‐2 infection results in upregulation of Plasminogen Activator Inhibitor‐1 and Neuroserpin in the lungs, and an increase in fibrinolysis inhibitors associated with disease severity

• https://pubmed.ncbi.nlm.nih.gov/37206290/
• Kevin H. Toomer, Gloria F. Gerber, ..., Ivo M. B. Francischetti (2023). EJHaem. 2023 Feb 23
• ELISA for Antithrombin (AT, SERPINC1, EA3301‐1), Thrombin‐antithrombin complex (TAT; ET1020‐1), α‐2‐Antiplasmin (A2AP, SERPINF2, EA3477‐1), Plasmin‐α2‐Antiplasmin Complex (PAP; EP1807‐1), Tissue Plasminogen Activator/Plasminogen Activator Inhibitor‐1 complex (t‐PA/PAI‐1; EP1105‐1), Factor XIII (FXIII; EF1013‐1), α‐1‐Antitrypsin (A1AT, SERPINA1; EA5101‐1), Protein Z (PZ; EP3333‐1), Protein C (PC, EP2312‐1), Protein S (total) (PS, EP133‐1), and Vaspin (SERPIN12; EV3005‐1) from Assaypro, LLC (St. Charles, MO).

Endothelial dysfunction in obstructive sleep apnea patients.

• https://pubmed.ncbi.nlm.nih.gov/33961199/
• Michał Harańczyk, Małgorzata Konieczyńska, Wojciech Płazak (2022). Sleep & breathing = Schlaf & Atmung. 2022 Mar 17
• .. three times.According to the manufacturer’s recommendations, the plasma for sICAM-1 was diluted three times.. Thrombin–antithrombin complexes were assessed in citrate plasma, using AssayMax™ Human Thrombin-Antithrombin Complex ELISA Kit (Assaypro, USA).. Readings were taken at a wavelength of 450 nm using an absorbance microplate reader ..

Circulatory Neutrophils Exhibit Enhanced Neutrophil Extracellular Trap Formation in Early Puerperium: NETs at the Nexus of Thrombosis and Immunity

• https://pubmed.ncbi.nlm.nih.gov/34948443/
• Stavros Giaglis, Chanchal Sur Chowdhury, ..., Bálint Nagy (2021). International Journal of Molecular Science…. 2021 Dec 20
• .. MPO/DNA complexes, a modified capture ELISA was utilized [ ].. The concentrations of thrombin-antithrombin (TAT) complexes and D-dimers were measured by sandwich ELISA, utilizing the human TAT Complexes ELISA Kit (Assaypro, St. Charles, MO, USA) and the Imuclone D-Dimer ELISA Kit (American Diagnostica, Pfungstadt, Germany) respectively.

The Comparison of Therapeutic Efficacy Between Dabigatran Versus Warfarin in Patients With Nonvalvular Atrial Fibrillation

• https://pubmed.ncbi.nlm.nih.gov/34559016/
• Hongxia Li, Lei Zhang, ..., Tingbo Jiang (2021). Clinical and Applied Thrombosis/Hemostasis. 2021 Sep 24
• STA® -PTT, STA® -Antithrombin III (ATIII), STA® -Thrombin, STA® -fibrinogen, STA® Néoplastine® CI reagent, Owren-Koller buffer, CaCl2 , Platelet-poor plasma (PPP) regent, thrombin calibrator, and FluCa were purchased from Stago (Asnières, France). F1+2 ELISA kit was from Dade Behring (Marburg, Germany). TAT ELISA kit was from Assaypro (MO, United States).

Angiotensin II triggers release of neutrophil extracellular traps, linking thromboinflammation with essential hypertension

• https://pubmed.ncbi.nlm.nih.gov/34324440/
• Akrivi Chrysanthopoulou, Eugenia Gkaliagkousi, ..., Panagiotis Skendros (2021). JCI insight. 2021 Sep 22
• .. 10 minutes at 37°C and immediately transferred on ice, to stop further thrombin activation.. The procedure was performed according to the manufacturer’s instructions (ET1020-1, Assaypro) and as previously described ( , ).. Isolated NET structures, treated for 30 minutes with either DNase I (1 U/mL; EN0525, ..

The role of Plasminogen Activator Inhibitor 1 in predicting sepsis-associated liver dysfunction: an observational study

• https://pubmed.ncbi.nlm.nih.gov/36981754/
• Ewa Woznica Niesobska, Patrycja Lesnik, Lidia Lysenko (2021). Research Square. 2021 Jan 07
• of collection. Levels of human hepcidin, IP-10, PAI-1, ET-1 were measured using quantikine ELISA tests (R Systems Inc., Minneapolis, MN, USA). Human TAT complex levels were measured using Assay Max (Assaypro LLC, St. Charles, USA). All assays employ the quantitative sandwich enzyme immunoassay technique. Tests were performed and interpreted according to the manufacturer's instructions. Taking SOFA

Oxidative Stress Product, 4-Hydroxy-2-Nonenal, Induces the Release of Tissue Factor-Positive Microvesicles From Perivascular Cells Into Circulation

• https://pubmed.ncbi.nlm.nih.gov/33028097/
• Shabbir A. Ansari, Shiva Keshava, L. Vijaya MohanL. Vijaya Mohan Rao Rao (2020). Arteriosclerosis, thrombosis, and vascular…. 2020 Oct 08
• The clot times were recorded using STart coagulizer (Diagnostica Stago).. Thrombin: antithrombin (TAT) levels in murine plasma were measured in an ELISA using a commercially available TAT assay kit (Assaypro, St Charles, MO) by following the protocol included in the kit.. Cytokines LevelsLevels of IL (interleukin)-6 and CXCL1/KC (murine IL-8 equivalent) in the plasma were ..

Selective potassium uptake via biocompatible zeolite–polymer hybrid microbeads as promising binders for hyperkalemia

• https://pubmed.ncbi.nlm.nih.gov/32995679/
• ZhoujunZhoujun Wang Wang, WeiWei Sun Sun, XinXin Song Song (2020). Bioactive Materials. 2020 Sep 12
• .. from the suspensions were observed under an Olympus IX53 microscope.. Complement activation, contact activation and platelet activation were evaluated by an enzyme-linked immune sorbent assay with Human Complement Fragment 3a (C3a) kit, Human Complement Fragment 5a (C5a) kit (BD Biosciences), thrombin-antithrombin III (TAT) kit (Assaypro LLC) and Human Platelet Factor 4 (PF4) kit (Hyphen BioMed).. 3.1 Evaluation of binding agents for microbeads Six candidates as ..

Role of Autophagy in Von Willebrand Factor Secretion by Endothelial Cells and in the In Vivo Thrombin-Antithrombin Complex Formation Promoted by the HIV-1 Matrix Protein p17

• https://pubmed.ncbi.nlm.nih.gov/32188077/
• Antonella Bugatti, Stefania Marsico, ..., Francesca Caccuri (2020). International Journal of Molecular Science…. 2020 Mar 16
• .. not with 1, 10, 100 or 250 ng/mL of p17/mouse ( n = 5/groups).. Citrated plasma samples were collected at 30 and 60 min following p17 injection and analyzed for the presence of TAT complexes by ELISA (Assaypro LLC., St. Charles, MO, USA).. Results were expressed as concentration of TAT compared to values of not treated (NT) ..

Increased perihematomal neuron autophagy and plasma thrombin–antithrombin levels in patients with intracerebral hemorrhage

• https://pubmed.ncbi.nlm.nih.gov/31574813/
• Chenghan Wu, Xiaohua Yan, ..., Feng Lu (2019). Medicine. 2019 Sep 01
• .. stored at 70°C for further processing.Plasma samples were stored at 70°C for further processing.. TAT complex concentrations in plasma samples were determined at Shanghai Institute of Immunology, China, using commercially available Assay Max Human TAT Complex enzyme-linked immunosorbent assay (ELISA) kit (ASSAYPRO, St. Charles, MO) as previously described.

Interaction of Blood Plasma Proteins with Superhemophobic Titania Nanotube Surfaces

• https://pubmed.ncbi.nlm.nih.gov/31279063/
• Roberta Maia Sabino, Kirsten Kauk, ..., Ketul C. Popat (2019). Nanomedicine: Nanotechnology, Biology and …. 2019 Jul 03
• TAT complex formation on different substrates exposed to platelet poor plasma (PPP) was investigated using a human TAT Complex ELISA kit (AssayPro).. Sterilized substrates were incubated in PPP on a horizontal shaker plate (100 rpm) for ..

Systemic Hyperfibrinolysis after Trauma: A Pilot study of Targeted Proteomic Analysis of Superposed Mechanisms in Patient Plasma

• https://pubmed.ncbi.nlm.nih.gov/29554044/
• Anirban Banerjee, Christopher C Silliman, ..., Kirk Hansen (2019). The journal of trauma and acute care surge…. 2019 Jun 01
• quantification, per the manufacturer’s instructions. ELISA’s were completed for thrombin (MyBiosource.com, San Diego, CA), antithrombin (AT), thrombin:antithrombin (TAT) complexes, plasminogen (Plg) (AssayPro, St. Charles, MO), α2 -antiplasmin, plasmin: α2 -antiplasmin (PAP) complexes, tPA, tPA:PAI-1 complexes and PAI-1 (Molecular Innovations, Novi, MI), and thrombin-activated fibrinolysis inhibito

In vitro and in vivo anticoagulant activity of heparin-like biomacromolecules and the mechanism analysis for heparin-mimicking activity

• https://pubmed.ncbi.nlm.nih.gov/30399381/
• Lang Ma, Jianbo Huang, ..., Feng Yan (2019). International Journal of Biological Macrom…. 2019 Feb 01
• Abstract: Heparin-like biomacromolecules (HepLBm), exhibiting similar chemical structure and biological properties to heparin, can be obtained by modifying either synthetic biopolymers or natural biom…

Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study

• https://pubmed.ncbi.nlm.nih.gov/30701381/
• Felix Carl Fabian Schmitt, Vasil Manolov, ..., Thorsten Brenner (2019). Annals of Intensive Care. 2019 Jan 30
• Plasma levels of thrombin–antithrombin complex (TAT), plasminogen activator inhibitor 1 (PAI-1), free tissue plasminogen activator (tPA) and total tissue plasminogen activator (total tPA) were measured using enzyme-linked immunosorbent assay (ELISA) kits according to the manufacturer’s instructions (Assaypro, St. Charles, USA). ELISA measurements were performed in duplicate.

Higher Thrombin-Antithrombin III Complex Levels May Indicate Severe Acute Pancreatitis.

• https://pubmed.ncbi.nlm.nih.gov/29332096/
• Sami Fidan, Murat Erkut, ..., Mehmet Arslan (2018). Digestive diseases (Basel, Switzerland). 2018 May 28
• In the study examining the relationship between thrombin-antithrombin III complex levels and acute pancreatitis, the Human Thrombin Antithrombin Complex TAT AssayMax ELISA Kit from Ass…

REDD1/Autophagy Pathway Is Associated with Neutrophil-Driven IL-1β Inflammatory Response in Active Ulcerative Colitis

• https://pubmed.ncbi.nlm.nih.gov/29712770/
• Iliana Angelidou, Akrivi Chrysanthopoulou, ..., Panagiotis Skendros (2018). The Journal of Immunology. 2018 Apr 30
• T structures. NET structures were introduced in plasma at a final concentration of 20%. Then, plasma was incubated for 10 min at 37˚C and immediately transferred on ice to stop further thrombin activation. The concentration of thrombin–antithrombin (TAT) complex was performed according to manufacturer’s instructions (Assaypro). The minimum detectable concentration of the TAT complex was 300 pg/ml.

Rationally designed magnetic nanoparticles as anticoagulants for blood purification

• https://pubmed.ncbi.nlm.nih.gov/29413611/
• Weifeng Zhao, Qiang Liu (2018). Colloids and Surfaces B: Biointerfaces. 2018 Apr 01
• Abstract: Heparin-based anticoagulant drugs are widely used for the prevention of blood clotting during extracorporeal circuit (bloodlines or cassette system) and surgical procedures as well as for th…

Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet

• https://pubmed.ncbi.nlm.nih.gov/20626618/
• F Li, C-H Wang, ..., N Takahashi (2017). Journal of thrombosis and haemostasis : JT…. 2017 Dec 27
• Plasma CML was measured with an ELISA kit (CycLex Co.).. Plasma thrombin-antithrombin (TAT) complexes were measured with the AssayMax TAT complexes ELISA kit (Assaypro Co.).. For PT and aPTT determination, blood was collected in glass tubes containing 3.8% trisodium ..

Neutrophil Extracellular Traps Promote Hypercoagulability in Patients With Sepsis

• https://pubmed.ncbi.nlm.nih.gov/27617671/
• Shuofei Yang, Haozhe Qi, ..., Lan Zhang (2017). Shock. 2017 Feb 01
• Abstract: Patients with sepsis commonly exhibit a hypercoagulability with high risk of venous thromboembolism (VTE). Neutrophil extracellular traps (NETs) are found to trigger inflammation and coagula…

Heparin-Like Chitosan Hydrogels with Tunable Swelling Behavior, Prolonged Clotting Times, and Prevented Contact Activation and Complement Activation

• https://pubmed.ncbi.nlm.nih.gov/27936718/
• Xuelian Huang, Rui Wang (2016). Biomacromolecules. 2016 Nov 17
• Abstract: The aim of this study was to create heparin-like chitosan hydrogels (HLCHs) for blood purification. Herein, we prepared two heparin-like chitosans (HLCSs) with various carboxymethyl and sulf…

Super-Anticoagulant Heparin-Mimicking Hydrogel Thin Film Attached Substrate Surfaces to Improve Hemocompatibility

• https://pubmed.ncbi.nlm.nih.gov/27676251/
• Min He, Xiaofei Cui, ..., Changsheng Zhao (2016). Macromolecular Bioscience. 2016 Sep 27
• Abstract: In this study, heparin-mimicking hydrogel thin films are covalently attached onto poly(ether sulfone) membrane surfaces to improve anticoagulant property. The hydrogel films display honeycom…

Histones stimulate von Willebrand factor release in vitro and in vivo

• https://pubmed.ncbi.nlm.nih.gov/27013650/
• Fong W Lam, Miguel A Cruz, ..., Rolando E Rumbaut (2016). Haematologica. 2016 Jul 12
• , we then determined the effects of histones on VWF release in vivo . In addition to measuring plasma VWF levels, we also measured circulating platelet counts and thrombin-antithrombin (TAT) levels (Assaypro LLC), which are altered in experimental and clinical sepsis. 9 , 15 All animal procedures were approved by the Institutional Animal Care and Use Committee. CTH (75 mg/kg) 1 or phosphate buff

Coagulation, thrombophilia and patency of arteriovenous fistula in children undergoing haemodialysis compared with healthy volunteers

• https://pubmed.ncbi.nlm.nih.gov/26829282/
• Fatina I. Fadel, Manal F. Elshamaa, ..., Mostafa El-Ahmady (2016). Blood Coagulation & Fibrinolysis. 2016 Mar 01
• In the study, the Human Thrombin Antithrombin Complex TAT AssayMax ELISA Kit from Assaypro was utilized to measure thrombin-antithrombin TAT complexes in plasma samples from children u…

Nanofibrous polymeric beads from aramid fibers for efficient bilirubin removal

• https://pubmed.ncbi.nlm.nih.gov/27481656/
• Zihang Peng, Ye Yang, ..., Changsheng Zhao (2016). Biomaterials Science. 2016 Jan 01
• Abstract: Polymer based hemoperfusion has been developed as an effective therapy to remove the extra bilirubin from patients. However, the currently applied materials suffer from either low removal ef…

Effect of heart rate control on coagulation status in patients of rheumatic mitral stenosis with atrial fibrillation – A pilot study ☆

• https://pubmed.ncbi.nlm.nih.gov/26688152/
• Jamal Yusuf, Mayank Goyal, ..., Vijay Trehan (2015). Indian Heart Journal. 2015 Dec 16
• cerebio, China; normal human plasma values are 31.2–2000 pmol/ml; intra- and inter-assay coefficient of variation of < 8% and < 10%, respectively) and plasma TAT (enzyme linked immunosorbent assay; Assaypro, USA; normal human plasma values are 0.5–10 ng/ml; intra- and inter-assay coefficients of variation were < 5% and < 8%) concentrations as markers of in vivo thrombin generation were measured

Promotion of Hypercoagulability in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis by C5a-Induced Tissue Factor-Expressing Microparticles and Neutrophil Extracellular Traps

• https://pubmed.ncbi.nlm.nih.gov/26097236/
• Yi-Min Huang, Huan Wang (2015). Arthritis & Rheumatology. 2015 Sep 23
• Abstract: Patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) have a high frequency of venous thromboembolic events and a hypercoagulable state. As C5a-primed neutrophils pla…

Layer by layer assembly of sulfonic poly(ether sulfone) as heparin-mimicking coatings: scalable fabrication of super-hemocompatible and antibacterial membranes

• https://pubmed.ncbi.nlm.nih.gov/32264490/
• Lingren Wang, Baihai Su, ..., Changsheng Zhao (2015). Journal of Materials Chemistry B. 2015 Jan 01
• Abstract: In this study, to approach the scalable fabrication of super-hemocompatible and antibacterial membranes, surface engineered 3D heparin-mimicking coatings were designed by layer by layer (LBL…

Coagulation, Fibrinolysis and Inhibitors in Failing Filters during Continuous Venovenous Hemofiltration in Critically Ill Patients with Acute Kidney Injury: Effect of Anticoagulation Modalities

• https://pubmed.ncbi.nlm.nih.gov/25966765/
• Louise Schilder, S. Azam Nurmohamed (2015). Blood purification. 2015 Jan 01
• Abstract: The mechanisms of early filter failure and clotting with different anticoagulation modalities during continuous venovenous hemofiltration (CVVH) are largely unknown. Citrate, heparin and no …

Increased thrombotic and impaired fibrinolytic response to acute exercise in patients with essential hypertension: The effect of treatment with an angiotensin II receptor blocker

• https://pubmed.ncbi.nlm.nih.gov/24621621/
• E Gavriilaki, E Gkaliagkousi, ..., S Douma (2014). Journal of human hypertension. 2014 Mar 13
• Human Thrombin-Antithrombin Complex (TAT) AssayMax ELISA Kit from Assaypro was instrumental in measuring TAT complexes, providing critical insights into the coagulation status of patie…

Biologically inspired membrane design with a heparin-like interface: prolonged blood coagulation, inhibited complement activation, and bio-artificial liver related cell proliferation

• https://pubmed.ncbi.nlm.nih.gov/32481812/
• Shengqiang Nie, Min Tang (2014). Biomater. Sci.. 2014 Jan 01
• Abstract: In the present work, inspired by the chemical structure of heparin molecules, we designed a polyethersulfone (PES) membrane with a heparin-like surface for the first time by physically blend…

Thrombin activatable fibrinolysis inhibitor (TAFI) levels in hypertensive patients and a comparison of the effects of amlodipine and ramipril on TAFI levels.

• https://pubmed.ncbi.nlm.nih.gov/22799880/
• Gulsum Ozkan, Sukru Ulusoy, ..., Ozlen Bektaş (2013). Clinical and experimental hypertension (Ne…. 2013 Sep 16
• In the study, the Human Thrombin-Antithrombin Complex (TAT) AssayMax ELISA Kit from Assaypro was employed to measure thrombin-antithrombin complex levels in plasma samples from hyperte…

Behçet’s disease: new insight into the relationship between procoagulant state, endothelial activation/damage and disease activity

• https://pubmed.ncbi.nlm.nih.gov/23711081/
• Ihosvany Fernández-Bello, Francisco J López-Longo, ..., Nora V Butta (2013). Orphanet Journal Of Rare Diseases. 2013 May 27
• .. (CRP) was measured by nephelometric method (Behring Nephelometer Analyzer, Germany).. Thrombin-antithrombin III complex (TAT) (AssayMax Human Thrombin-antithrombin Complexes ELISA Kit, ASSAYPRO, St. Charles, MO, USA) and E-selectin (ES) (Human sE-Selectin/CD26E Immunoassay Quantikine © ELISA kit, R&D Systems Europe Ltd., Abingdon, UK) were measured in PPP, following the manufacturer’s instructions.. The fibrinolytic profile was evaluated by assessing plasma antigenic levels ..

Thrombin-cleaved Fragments of Osteopontin Are Overexpressed in Malignant Glial Tumors and Provide a Molecular Niche with Survival Advantage *

• https://pubmed.ncbi.nlm.nih.gov/23204518/
• Yasuto Yamaguchi, Zhifei Shao, ..., Lawrence L K Leung (2013). The Journal of Biological Chemistry. 2013 Feb 01
• Recombinant OPN-R and OPN-L (0.625 ng/ml-50 ng/ml) were used to construct the calibration curves.. Levels of thrombin-antithrombin complexes (TAT) were determined using a commercial ELISA kit (Assaypro, St. Charles, MO).. VEGF, TNF-α, chemokine (C-C motif) ligand 3 (CCL3, also known as macrophage inflammatory protein ..

Thrombin activatable fibrinolysis inhibitor and thrombin-antithrombin-III-complex levels in patients with gastric cancer.

• https://pubmed.ncbi.nlm.nih.gov/22535370/
• Evren Fidan, Halil Kavgaci, ..., Fazil Aydin (2012). Tumour biology : the journal of the Intern…. 2012 Dec 26
• In the study examining the relationship between gastric cancer and coagulation, the Human Thrombin Antithrombin Complex TAT AssayMax ELISA Kit from Assaypro was instrumental in measuri…

Proteomics-based identification of haptoglobin as a favourable serum biomarker for predicting long-term response to splenectomy in patients with primary immune thrombocytopenia

• https://pubmed.ncbi.nlm.nih.gov/23039040/
• Chao-Xu Zheng, Zhuang-Qi Ji, Dong Zheng (2012). Journal of Translational Medicine. 2012 Oct 07
• .. in serum, serum samples from ITP patients and healthy controls were analysed by ELISA.. The concentrations of Hp in serum were determined using an AssayMax human Hp ELISA kit according to the manufacturer's protocol (Assaypro, Winfield, MO, USA).. The concentrations of Hp in serum were determined using an AssayMax human Hp ELISA ..

Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

• https://pubmed.ncbi.nlm.nih.gov/23029002/
• Konstantinos Kambas, Ioannis Mitroulis, ..., Konstantinos Ritis (2012). PLoS ONE. 2012 Sep 19
• wards, culture supernatants were collected and centrifuged at 300×g to remove any cells and at 16000×g to eliminate cellular debris. Isolated NETs structures were added in RPMI with 6% serum for 30 min. The concentration of thrombin-antithrombin (TAT) complex was measured according to manufacturer’s instructions (Assaypro, Winfield, MO, USA). The minimum detectable dose of the assay was 300 pg/ml.

The relationship between aortic aneurysm sac thrombus volume on coagulation, fibrinolysis and platelet activity

• https://pubmed.ncbi.nlm.nih.gov/22497884/
• Robert S.M. Davies, Mohamed Abdelhamid, ..., Donald J. Adam (2012). Thrombosis research. 2012 Sep 01
• In the study examining the relationship between thrombus volume and coagulation in abdominal aortic aneurysms, the Human Thrombin-Antithrombin Complex (TAT) AssayMax ELISA Kit from Ass…

Thrombosis from a prothrombin mutation conveying antithrombin resistance.

• https://pubmed.ncbi.nlm.nih.gov/22716977/
• Yuhri Miyawaki, Atsuo Suzuki, ..., Tetsuhito Kojima (2012). The New England journal of medicine. 2012 Jun 26
• In the study, the Human Thrombin Antithrombin Complex TAT AssayMax ELISA Kit from Assaypro was utilized to measure thrombin–antithrombin complex formation, which was essential for asse…

Analysis of thrombin-antithrombin complex contents in plasma and hematoma fluid of hypertensive intracerebral hemorrhage patients after clot removal.

• https://pubmed.ncbi.nlm.nih.gov/21244583/
• C-H Wu, R-L Yang, ..., L-D Chen (2012). European journal of neurology. 2012 May 17
• In the study on hypertensive intracerebral hemorrhage, the Human Thrombin Antithrombin Complex TAT AssayMax ELISA Kit from Assaypro was essential for quantifying TAT complex concentrat…

Prospective study of the incidence and predictors of thrombus in children undergoing palliative surgery for single ventricle physiology

• https://pubmed.ncbi.nlm.nih.gov/21979273/
• Deanna R Todd Tzanetos, Chang Yu, ..., Nancy J Brown (2011). Intensive care medicine. 2011 Oct 07
• TAT complexes (AssayMax Human TAT Complexes ELISA Kit, Assaypro, St. Charles, MO, USA) and TFPI (Quantikine® Human TFPI Immunoassay, R & D Systems, Minneapolis, MN, USA) levels were measured with a quantitative sandwich enzyme immunoassay technique. sCD40L was measured using an enzyme immunoassay (Quantikine® Human soluble CD40 Ligand Immunoassay, R & D Systems, Minneapolis, MN, USA). tPA plasma antigen levels (TintElize® tPA, Trinity Biotech, Ireland), PAI-1 antigen levels (TriniL-IZE ..

Monomeric C-reactive protein is prothrombotic and dissociates from circulating pentameric C-reactive protein on adhered activated platelets under flow

• https://pubmed.ncbi.nlm.nih.gov/21859817/
• Blanca Molins, Esther Peña, ..., Lina Badimon (2011). Cardiovascular Research. 2011 Aug 22
• Levels of thrombin–antithrombin (TAT) were measured by enzyme immunoassay (Assay Pro) and tissue factor-procoagulant activity (TF-PCA) was measured by using a factor (F) Xa generation test. ow nloaded from https://academ ic.oup.com /cardiovascres/article/92/2/328/377833 by guest on 04 Septem ber 2022.

Alkali treatment of microrough titanium surfaces affects macrophage/monocyte adhesion, platelet activation and architecture of blood clot formation

• https://pubmed.ncbi.nlm.nih.gov/21604243/
• V Milleret, S Tugulu, ..., H Hall (2011). European Cells and Materials. 2011 May 22
• In the study, the Human Thrombin-Antithrombin Complex (TAT) AssayMax ELISA Kit from Assaypro was utilized to analyze platelet activation and blood clot formation on titanium surfaces. …

Evaluation of various endothelial biomarkers in ankylosing spondylitis

• https://pubmed.ncbi.nlm.nih.gov/21556780/
• Ali Taylan, Ismail Sari (2011). Clinical rheumatology. 2011 May 10
• Abstract: Atherosclerosis has been shown to be increased in chronic inflammatory diseases including ankylosing spondylitis (AS). Impaired endothelial function, the first step in atherosclerosis, may b…

Stability of coagulation factors in plasma prepared after a 24-hour room temperature hold

• https://pubmed.ncbi.nlm.nih.gov/20412526/
• Hiba Alhumaidan, Tracey Cheves, ..., Joseph Sweeney (2010). Transfusion. 2010 Apr 15
• Abstract: The manufacture of fresh-frozen plasma (FFP) requires that plasma be frozen within 8 hours of collection and 24-hour frozen plasma requires 1 to 6°C refrigeration before freezing. Manufactur…

The Role of Fibrinolytic and Antifibrinolytic Activities in the Pathophysiology of HELLP Syndrome

• https://pubmed.ncbi.nlm.nih.gov/19943771/
• Suleyman Guven, Mehmet Sonmez, S. Caner Karahan (2009). Hypertension in pregnancy. 2009 Nov 27
• In the study investigating HELLP Syndrome, the Human Thrombin-Antithrombin Complex (TAT) AssayMax ELISA Kit from Assaypro played a significant role by measuring TAT levels. This assay …

Thrombin activatable fibrinolysis inhibitor and other hemostatic parameters in patients with polycystic ovary syndrome

• https://pubmed.ncbi.nlm.nih.gov/19253106/
• Baha Oral, Betül Mermi, ..., Recep Sütçü (2009). Gynecological Endocrinology. 2009 Jan 01
• In this study, the Human Thrombin-Antithrombin Complex (TAT) AssayMax ELISA Kit from Assaypro was utilized to measure TAT levels in plasma samples from women with polycystic ovary synd…