Mouse Thrombin-Antithrombin (TAT) Complex ELISA Kit

$407.00

Catalog Number: EMT1020-1

This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Product Size:96 Well Plate

Catalog Number. EMT1020-1 Categories: , , Tag: Brand:

Additional information

Format

Sandwich ELISA

Entrez Gene

14062

Components

Biotinylated Mouse TAT Complex Antibody, Chromogen Substrate (1x), EIA Diluent Concentrate (10x), Mouse TAT Complex Microplate, Mouse TAT Complex Standard, Sealing Tapes, SP Conjugate (100x), Stop Solution (1x), Wash Buffer Concentrate (20x)

TIme

4 hours

Sensitivity

1.5 pg/ml

Range

1.953 – 500 pg/ml

Samples Type

Plasma, Serum

Associated Disease

Diabetes

Species

Mouse

UniProt

P19221

Storage

Refer to component labels for details

Plex

1

Usage

For Research Use Only, Not To Be Used For Diagnostic Purposes

Documentation

Publications (24 results)

Please use discretion when following external links; Assaypro cannot guarantee the validity and security of all citation links provided.

Coagulation and Fibrinolysis Profiles in Mouse Breast Cancer 4T1 Tumor-Bearing Mice: A Characterization of Neutrophil-Associated Prothrombotic States

Acid sphingomyelinase plays a critical role in LPS-and cytokine-induced tissue factor procoagulant activity

  • https://ashpublications.org/blood/article-abstract/134/7/645/260728
  • J Wang, UR Pendurthi, LVM Rao - Blood, The Journal of the …, 2019 - ashpublications.org
  • Tissue factor (TF) is a cofactor for factor VIIa and the primary cellular initiator of coagulation. Typically, most TF on cell surfaces exists in a cryptic coagulant-inactive state but are …

Leukocytes as a reservoir of circulating oncogenic DNA and regulatory targets of tumor‐derived extracellular vesicles

  • https://www.sciencedirect.com/science/article/pii/S1538783622023595
  • S Chennakrishnaiah, B Meehan, E D'asti… - Journal of Thrombosis …, 2018 - Elsevier
  • Essentials • Tumor‐bearing mice were employed to follow oncogenic HRAS sequences in plasma, and blood cells. • Cancer DNA accumulated in leukocytes above levels detected in …

Neutrophil extracellular trap stabilization by platelet factor 4 reduces thrombogenicity and endothelial cell injury

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC9881987/
  • ATP Ngo, A Sarkar, I Yarovoi, ND Levine… - …, 2023 - pmc.ncbi.nlm.nih.gov
  • … Thrombin anti-thrombin complexes in septic plasma were measured using commercially available ELISA kits (AssayPro; EMT1020–1) according to manufacturers’ instructions. Briefly, …

Platelet factor 4 limits neutrophil extracellular trap–and cell-free DNA–induced thrombogenicity and endothelial injury

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10721321/
  • ATP Ngo, A Skidmore, J Oberg, I Yarovoi, A Sarkar… - JCI …, 2023 - pmc.ncbi.nlm.nih.gov
  • … To assess thrombin generation in murine septic plasma, TAT complexes were measured by ELISA kit (AssayPro, EMT1020-1) as follows: citrated plasma was diluted 125-fold and …

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

  • https://rupress.org/jem/article-abstract/214/7/2121/52170
  • S Uderhardt, JA Ackermann, T Fillep… - Journal of Experimental …, 2017 - rupress.org
  • Blood coagulation is essential for physiological hemostasis but simultaneously contributes to thrombotic disease. However, molecular and cellular events controlling initiation and …

Vascular protein disulfide isomerase A1 mediates endothelial dysfunction induced by angiotensin II in mice

  • https://onlinelibrary.wiley.com/doi/abs/10.1111/apha.14116
  • A Kij, A Bar, I Czyzynska‐Cichon… - Acta …, 2024 - Wiley Online Library
  • Aim Protein disulfide isomerases (PDIs) are involved in platelet aggregation and intravascular thrombosis, but their role in regulating endothelial function is unclear. Here, we …

Extracellular Vesicle–Mediated Trafficking of Oncogenic DNA in the Tumour Microenvironment and Biofluids

* Keshava S et al. (2020) Therapeutic doses of recombinant factor VIIa in hemophilia generates thrombin in platelet-dependent and -independent mechanisms. J Thromb Haemost. 18(8):1911-1921.

* Wang J et al. (2019) Acid sphingomyelinase plays a critical role in LPS- and cytokine-induced tissue factor procoagulant activity. Blood 134 (7): 645-655.

* Senchenkova EY (2019) Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation. Circulation. 140(4):319-335.

* Castillo MM et al. (2019) Maintaining extraembryonic expression allows generation of mice with severe tissue factor pathway inhibitor deficiency. Blood Adv. 3(3): 489?498

* Shan Z et al. (2018) Chitinase 3-Like-1 Promotes Intrahepatic Activation of Coagulation Through Induction of Tissue Factor in Mice. Hepatology. 67(6):2384-2396

* Yang D et al. (2017) Angiotensin II promotes the anticoagulant effects of rivaroxaban via angiotensin type 2 receptor signaling in mice. Sci Rep. 7(1):369

* Hayashi S et al. (2017) Protease-activated receptor 2 exacerbates adenine-induced renal tubulointerstitial injury in mice.Biochem Biophys Res Commun. 483(1):547-552.

* El Kebir D et al. (2015) Toll-Like Receptor 9 Signaling Regulates Tissue Factor and Tissue Factor Pathway Inhibitor Expression in Human Endothelial Cells and Coagulation in Mice. Crit Care Med. 43(6):e179-89

* Alexander ET et al. (2015) Thrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis. Cancer Biol Ther. 16(12):1802-11

* Kothari H et al (2014) Role of Tissue Factor in Mycobacterium tuberculosis-Induced Inflammation and Disease Pathogenesis. PLoS One. 9(12):e114141

* Rajcic D et al. (2021) Citrulline supplementation attenuates the development of non-alcoholic steatohepatitis in female mice through mechanisms involving intestinal arginase. Redox Biol. 41:101879.

* Salman TM et al. (2014) Protective effect of proanthocyanidins on nephrotoxicity induced by antitumor dose of cisplatin in ehrlich solid tumor-bearing mice. Arab. J. Lab. Med. 40(2):953-965.

* Esmat A et al. (2012) Anti-Inflammatory Activity of Pistacia khinjuk in Different Experimental Models: Isolation and Characterization of Its Flavonoids and Galloylated Sugars. J Med Food. 15(3):278-287

* Eren Z et al. (2012) Evaluation of the Effects of a High Dose of Erythropoietin-beta on Early Endotoxemia Using a Rat Model. Adv Clin Exp Med. 21(3):321?329

* El Akoum S et al. (2011) Nature of Fatty Acids in High Fat Diets Differentially Delineates Obesity-Linked Metabolic Syndrome Components in Male and Female C57BL/6J Mice. Diabetol Metab Syndr. 3(1):34

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